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Oral appliance therapy for obstructive sleep apnea.
Ng A, Gotsopoulos H, Darendeliler AM, Cistulli PA. Ng A, et al. Treat Respir Med. 2005;4(6):409-22. doi: 10.2165/00151829-200504060-00005. Treat Respir Med. 2005. PMID: 16336026 Review.
Obstructive sleep apnea (OSA) is a common disorder characterized by repetitive, complete or partial closure of the upper airway during sleep, resulting in sleep fragmentation and oxygen desaturation. ...Notwithstanding the expanding role of oral appliance therapy, there ar …
Obstructive sleep apnea (OSA) is a common disorder characterized by repetitive, complete or partial closure of the upper airway durin …
Oral Appliance Treatment Response and Polysomnographic Phenotypes of Obstructive Sleep Apnea.
Sutherland K, Takaya H, Qian J, Petocz P, Ng AT, Cistulli PA. Sutherland K, et al. Among authors: ng at. J Clin Sleep Med. 2015 Aug 15;11(8):861-8. doi: 10.5664/jcsm.4934. J Clin Sleep Med. 2015. PMID: 25845897 Free PMC article.
RESULTS: A total of 425 patients (109 female) were included (age 51.2 ± 10.9 years, BMI 29.2 ± 5.0 kg/m2). MAS reduced AHI by 50.3% ± 50.7% across the group. ...REM-predominant OSA showed a lower response rate than either NREM or non-stage dependent OSA. In predicti …
RESULTS: A total of 425 patients (109 female) were included (age 51.2 ± 10.9 years, BMI 29.2 ± 5.0 kg/m2). MAS reduced AHI by 50.3% ± …
Comparative effects of two oral appliances on upper airway structure in obstructive sleep apnea.
Sutherland K, Deane SA, Chan AS, Schwab RJ, Ng AT, Darendeliler MA, Cistulli PA. Sutherland K, et al. Among authors: ng at. Sleep. 2011 Apr 1;34(4):469-77. doi: 10.1093/sleep/34.4.469. Sleep. 2011. PMID: 21461325 Free PMC article. Clinical Trial.
Treatment efficacy was determined by polysomnography in a subset of 18 patients. MEASUREMENTS AND RESULTS: Upper airway lumen and surrounding soft tissue structures were segmented using image analysis software. ...TSD increased velopharyngeal lateral diameter to a g …
Treatment efficacy was determined by polysomnography in a subset of 18 patients. MEASUREMENTS AND RESULTS: Upper airway lumen and sur …
Comparison of mandibular advancement splint and tongue stabilizing device in obstructive sleep apnea: a randomized controlled trial.
Deane SA, Cistulli PA, Ng AT, Zeng B, Petocz P, Darendeliler MA. Deane SA, et al. Among authors: ng at. Sleep. 2009 May;32(5):648-53. doi: 10.1093/sleep/32.5.648. Sleep. 2009. PMID: 19480232 Free PMC article. Clinical Trial.
STUDY OBJECTIVES: To compare the efficacy of a mandibular advancement splint (MAS) and a novel tongue stabilizing device (TSD) in the treatment of obstructive sleep apnea (OSA). DESIGN: A randomized crossover design was used. PATIENTS: Twenty-seven patients ( …
STUDY OBJECTIVES: To compare the efficacy of a mandibular advancement splint (MAS) and a novel tongue stabilizing device (TSD) …
Influence of nasal resistance on oral appliance treatment outcome in obstructive sleep apnea.
Zeng B, Ng AT, Qian J, Petocz P, Darendeliler MA, Cistulli PA. Zeng B, et al. Among authors: ng at. Sleep. 2008 Apr;31(4):543-7. doi: 10.1093/sleep/31.4.543. Sleep. 2008. PMID: 18457242 Free PMC article.
Thirty-eight patients with known OSA underwent polysomnography while wearing a custom-made MAS. Treatment outcome was defined as follows: Responders (R) > or =50% reduction in AHI, and Nonresponders (NR) as <50% reduction in AHI. ...
Thirty-eight patients with known OSA underwent polysomnography while wearing a custom-made MAS. Treatment outcome was defined as foll …
Use of flow-volume curves to predict oral appliance treatment outcome in obstructive sleep apnea.
Zeng B, Ng AT, Darendeliler MA, Petocz P, Cistulli PA. Zeng B, et al. Among authors: ng at. Am J Respir Crit Care Med. 2007 Apr 1;175(7):726-30. doi: 10.1164/rccm.200608-1205OC. Epub 2007 Jan 11. Am J Respir Crit Care Med. 2007. PMID: 17218619
Hence there is a need for a simple and reliable clinical tool to assist in the differentiation of treatment responses. We hypothesized that abnormalities of flow-volume curves, together with other clinical variables, may have clinical utility in the prediction of MA …
Hence there is a need for a simple and reliable clinical tool to assist in the differentiation of treatment responses. We hypo …
Effect of oral appliance therapy on upper airway collapsibility in obstructive sleep apnea.
Ng AT, Gotsopoulos H, Qian J, Cistulli PA. Ng AT, et al. Am J Respir Crit Care Med. 2003 Jul 15;168(2):238-41. doi: 10.1164/rccm.200211-1275OC. Epub 2003 Apr 30. Am J Respir Crit Care Med. 2003. PMID: 12724125 Clinical Trial.
We examined the effect of a mandibular advancement splint (MAS) on upper airway collapsibility during sleep in OSA. Ten patients with proven OSA had a custom-made MAS incrementally adjusted during an acclimatization period until the maximum comfortable limit of mand …
We examined the effect of a mandibular advancement splint (MAS) on upper airway collapsibility during sleep in OSA. Ten patients with …
Oropharyngeal collapse predicts treatment response with oral appliance therapy in obstructive sleep apnea.
Ng AT, Qian J, Cistulli PA. Ng AT, et al. Sleep. 2006 May;29(5):666-71. Sleep. 2006. PMID: 16774157
MEASUREMENTS AND RESULTS: A baseline diagnostic polysomnogram confirmed AHI > or = 10 per hour. During the following acclimatization period, a custom-made adjustable MAS was incrementally advanced until maximum comfortable mandibular protrusion was reached. A
MEASUREMENTS AND RESULTS: A baseline diagnostic polysomnogram confirmed AHI > or = 10 per hour. During the following acclimatizati …
Cephalometry and prediction of oral appliance treatment outcome.
Ng AT, Darendeliler MA, Petocz P, Cistulli PA. Ng AT, et al. Sleep Breath. 2012 Mar;16(1):47-58. doi: 10.1007/s11325-011-0484-2. Epub 2011 Mar 19. Sleep Breath. 2012. PMID: 21424283
METHODS: Anthropomorphic measurements and cephalometric X-rays from 72 OSA patients who had presented to a tertiary referral sleep clinic were analyzed retrospectively. ...A good response occurred in 56% (40 patients) according to criterion 1; 54% (39 patients) acco …
METHODS: Anthropomorphic measurements and cephalometric X-rays from 72 OSA patients who had presented to a tertiary referral sleep cl …
Role of venous blood gases in hypercapnic respiratory failure chronic obstructive pulmonary disease patients presenting to the emergency department.
Wong EKC, Lee PCS, Ansary S, Asha S, Wong KKH, Yee BJ, Ng AT. Wong EKC, et al. Among authors: ng at. Intern Med J. 2019 Jul;49(7):834-837. doi: 10.1111/imj.14186. Intern Med J. 2019. PMID: 30515940
A subsequent VBG was also taken, and Bland-Altman plots were used for analysis. RESULTS: Sixty-three patients were included in this study. ...Wider limits of agreement with a systematic bias of 7.7 mmHg were noted with pCO(2) . CONCLUSIONS: The utility of VBG pH and
A subsequent VBG was also taken, and Bland-Altman plots were used for analysis. RESULTS: Sixty-three patients were included in this s
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