Nghiem P - Search Results

1

ATR regulates fragile site stability.

Casper AM, Nghiem P, Arlt MF, Glover TW. Casper AM, et al. Among authors: nghiem p. Cell. 2002 Dec 13;111(6):779-89. doi: 10.1016/s0092-8674(02)01113-3. Cell. 2002. PMID: 12526805

2

DGCR8 Mediates Repair of UV-Induced DNA Damage Independently of RNA Processing.

Calses PC, Dhillon KK, Tucker N, Chi Y, Huang JW, Kawasumi M, Nghiem P, Wang Y, Clurman BE, Jacquemont C, Gafken PR, Sugasawa K, Saijo M, Taniguchi T. Calses PC, et al. Among authors: nghiem p. Cell Rep. 2017 Apr 4;19(1):162-174. doi: 10.1016/j.celrep.2017.03.021. Cell Rep. 2017. PMID: 28380355 Free PMC article.

3

ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation.

Nghiem P, Park PK, Kim Y, Vaziri C, Schreiber SL. Nghiem P, et al. Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9092-7. doi: 10.1073/pnas.161281798. Proc Natl Acad Sci U S A. 2001. PMID: 11481475 Free PMC article.

4

ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: potential basis for the UV protective effects of caffeine.

Heffernan TP, Kawasumi M, Blasina A, Anderes K, Conney AH, Nghiem P. Heffernan TP, et al. Among authors: nghiem p. J Invest Dermatol. 2009 Jul;129(7):1805-15. doi: 10.1038/jid.2008.435. Epub 2009 Feb 26. J Invest Dermatol. 2009. PMID: 19242509 Free PMC article.

5

Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R.

Roshal M, Kim B, Zhu Y, Nghiem P, Planelles V. Roshal M, et al. Among authors: nghiem p. J Biol Chem. 2003 Jul 11;278(28):25879-86. doi: 10.1074/jbc.M303948200. Epub 2003 May 8. J Biol Chem. 2003. PMID: 12738771

6

ATR is not required for p53 activation but synergizes with p53 in the replication checkpoint.

Nghiem P, Park PK, Kim Ys YS, Desai BN, Schreiber SL. Nghiem P, et al. J Biol Chem. 2002 Feb 8;277(6):4428-34. doi: 10.1074/jbc.M106113200. Epub 2001 Nov 15. J Biol Chem. 2002. PMID: 11711532

7

Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase.

Kawasumi M, Lemos B, Bradner JE, Thibodeau R, Kim YS, Schmidt M, Higgins E, Koo SW, Angle-Zahn A, Chen A, Levine D, Nguyen L, Heffernan TP, Longo I, Mandinova A, Lu YP, Conney AH, Nghiem P. Kawasumi M, et al. Among authors: nghiem p. Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13716-21. doi: 10.1073/pnas.1111378108. Epub 2011 Aug 15. Proc Natl Acad Sci U S A. 2011. PMID: 21844338 Free PMC article.

8

Integration of growth factor and nutrient signaling: implications for cancer biology.

Shamji AF, Nghiem P, Schreiber SL. Shamji AF, et al. Among authors: nghiem p. Mol Cell. 2003 Aug;12(2):271-80. doi: 10.1016/j.molcel.2003.08.016. Mol Cell. 2003. PMID: 14536067 Review.

9

Identification of ATR-Chk1 pathway inhibitors that selectively target p53-deficient cells without directly suppressing ATR catalytic activity.

Kawasumi M, Bradner JE, Tolliday N, Thibodeau R, Sloan H, Brummond KM, Nghiem P. Kawasumi M, et al. Among authors: nghiem p. Cancer Res. 2014 Dec 15;74(24):7534-45. doi: 10.1158/0008-5472.CAN-14-2650. Epub 2014 Oct 21. Cancer Res. 2014. PMID: 25336189 Free PMC article.

10

Effect of caffeine on the ATR/Chk1 pathway in the epidermis of UVB-irradiated mice.

Lu YP, Lou YR, Peng QY, Xie JG, Nghiem P, Conney AH. Lu YP, et al. Among authors: nghiem p. Cancer Res. 2008 Apr 1;68(7):2523-9. doi: 10.1158/0008-5472.CAN-07-5955. Cancer Res. 2008. PMID: 18381462 Free PMC article.

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