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Regulation of apoptosis by endoplasmic reticulum pathways.
Breckenridge DG, Germain M, Mathai JP, Nguyen M, Shore GC. Breckenridge DG, et al. Among authors: nguyen m. Oncogene. 2003 Nov 24;22(53):8608-18. doi: 10.1038/sj.onc.1207108. Oncogene. 2003. PMID: 14634622 Review.
Bcl-2-associated autophagy regulator Naf-1 required for maintenance of skeletal muscle.
Chang NC, Nguyen M, Bourdon J, Risse PA, Martin J, Danialou G, Rizzuto R, Petrof BJ, Shore GC. Chang NC, et al. Among authors: nguyen m. Hum Mol Genet. 2012 May 15;21(10):2277-87. doi: 10.1093/hmg/dds048. Epub 2012 Feb 15. Hum Mol Genet. 2012. PMID: 22343142
Obatoclax is a direct and potent antagonist of membrane-restricted Mcl-1 and is synthetic lethal with treatment that induces Bim.
Nguyen M, Cencic R, Ertel F, Bernier C, Pelletier J, Roulston A, Silvius JR, Shore GC. Nguyen M, et al. BMC Cancer. 2015 Aug 1;15:568. doi: 10.1186/s12885-015-1582-5. BMC Cancer. 2015. PMID: 26231047 Free PMC article.
Fis1, Bap31 and the kiss of death between mitochondria and endoplasmic reticulum.
Wang B, Nguyen M, Chang NC, Shore GC. Wang B, et al. Among authors: nguyen m. EMBO J. 2011 Feb 2;30(3):451-2. doi: 10.1038/emboj.2010.352. EMBO J. 2011. PMID: 21285974 Free PMC article.
The resident endoplasmic reticulum protein, BAP31, associates with gamma-actin and myosin B heavy chain.
Ducret A, Nguyen M, Breckenridge DG, Shore GC. Ducret A, et al. Among authors: nguyen m. Eur J Biochem. 2003 Jan;270(2):342-9. doi: 10.1046/j.1432-1033.2003.03395.x. Eur J Biochem. 2003. PMID: 12605685
Recently, we reported that the caspase-resistant BAP31 inhibited Fas-mediated apoptotic membrane fragmentation and the release of cytochrome c from mitochondria in KB epithelial cells (Nguyen M., Breckenridge G., Ducret A & Shore G. (2000) Mol. ...
Recently, we reported that the caspase-resistant BAP31 inhibited Fas-mediated apoptotic membrane fragmentation and the release of cytochrome …
The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum.
Breckenridge DG, Nguyen M, Kuppig S, Reth M, Shore GC. Breckenridge DG, et al. Among authors: nguyen m. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4331-6. doi: 10.1073/pnas.072088099. Epub 2002 Mar 26. Proc Natl Acad Sci U S A. 2002. PMID: 11917123 Free PMC article.
Uncleaved BAP31 in association with A4 protein at the endoplasmic reticulum is an inhibitor of Fas-initiated release of cytochrome c from mitochondria.
Wang B, Nguyen M, Breckenridge DG, Stojanovic M, Clemons PA, Kuppig S, Shore GC. Wang B, et al. Among authors: nguyen m. J Biol Chem. 2003 Apr 18;278(16):14461-8. doi: 10.1074/jbc.M209684200. Epub 2003 Jan 15. J Biol Chem. 2003. PMID: 12529377
Mitochondrion-dependent N-terminal processing of outer membrane Mcl-1 protein removes an essential Mule/Lasu1 protein-binding site.
Warr MR, Mills JR, Nguyen M, Lemaire-Ewing S, Baardsnes J, Sun KL, Malina A, Young JC, Jeyaraju DV, O'Connor-McCourt M, Pellegrini L, Pelletier J, Shore GC. Warr MR, et al. Among authors: nguyen m. J Biol Chem. 2011 Jul 15;286(28):25098-107. doi: 10.1074/jbc.M111.218321. Epub 2011 May 25. J Biol Chem. 2011. PMID: 21613222 Free PMC article.
Cadmium exposure induces mitochondria-dependent apoptosis in oligodendrocytes.
Hossain S, Liu HN, Nguyen M, Shore G, Almazan G. Hossain S, et al. Among authors: nguyen m. Neurotoxicology. 2009 Jul;30(4):544-54. doi: 10.1016/j.neuro.2009.06.001. Epub 2009 Jun 11. Neurotoxicology. 2009. PMID: 19523979
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