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Molecular phenotyping of a UK population: defining the human serum metabolome.
Dunn WB, Lin W, Broadhurst D, Begley P, Brown M, Zelena E, Vaughan AA, Halsall A, Harding N, Knowles JD, Francis-McIntyre S, Tseng A, Ellis DI, O'Hagan S, Aarons G, Benjamin B, Chew-Graham S, Moseley C, Potter P, Winder CL, Potts C, Thornton P, McWhirter C, Zubair M, Pan M, Burns A, Cruickshank JK, Jayson GC, Purandare N, Wu FC, Finn JD, Haselden JN, Nicholls AW, Wilson ID, Goodacre R, Kell DB. Dunn WB, et al. Among authors: Nicholls AW. Metabolomics. 2015;11:9-26. doi: 10.1007/s11306-014-0707-1. Epub 2014 Jul 25. Metabolomics. 2015. PMID: 25598764 Free PMC article.
Realising the potential of metabolomics.
Nicholls AW. Nicholls AW. Bioanalysis. 2012 Sep;4(18):2195-7. doi: 10.4155/bio.12.209. Bioanalysis. 2012. PMID: 23046260 No abstract available.
Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry.
Dunn WB, Broadhurst D, Begley P, Zelena E, Francis-McIntyre S, Anderson N, Brown M, Knowles JD, Halsall A, Haselden JN, Nicholls AW, Wilson ID, Kell DB, Goodacre R; Human Serum Metabolome (HUSERMET) Consortium. Dunn WB, et al. Among authors: Nicholls AW. Nat Protoc. 2011 Jun 30;6(7):1060-83. doi: 10.1038/nprot.2011.335. Nat Protoc. 2011. PMID: 21720319
Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links.
Rueedi R, Ledda M, Nicholls AW, Salek RM, Marques-Vidal P, Morya E, Sameshima K, Montoliu I, Da Silva L, Collino S, Martin FP, Rezzi S, Steinbeck C, Waterworth DM, Waeber G, Vollenweider P, Beckmann JS, Le Coutre J, Mooser V, Bergmann S, Genick UK, Kutalik Z. Rueedi R, et al. Among authors: Nicholls AW. PLoS Genet. 2014 Feb 20;10(2):e1004132. doi: 10.1371/journal.pgen.1004132. eCollection 2014 Feb. PLoS Genet. 2014. PMID: 24586186 Free PMC article.
Proposed minimum reporting standards for chemical analysis Chemical Analysis Working Group (CAWG) Metabolomics Standards Initiative (MSI).
Sumner LW, Amberg A, Barrett D, Beale MH, Beger R, Daykin CA, Fan TW, Fiehn O, Goodacre R, Griffin JL, Hankemeier T, Hardy N, Harnly J, Higashi R, Kopka J, Lane AN, Lindon JC, Marriott P, Nicholls AW, Reily MD, Thaden JJ, Viant MR. Sumner LW, et al. Among authors: Nicholls AW. Metabolomics. 2007 Sep;3(3):211-221. doi: 10.1007/s11306-007-0082-2. Metabolomics. 2007. PMID: 24039616 Free PMC article.
Metabolomics dataset of PPAR-pan treated rat liver.
Ament Z, West JA, Stanley E, Li X, Ashmore T, Roberts LD, Wright J, Nicholls AW, Griffin JL. Ament Z, et al. Among authors: Nicholls AW. Data Brief. 2016 May 10;8:196-202. doi: 10.1016/j.dib.2016.05.002. eCollection 2016 Sep. Data Brief. 2016. PMID: 27331087 Free PMC article.
PPAR-pan activation induces hepatic oxidative stress and lipidomic remodelling.
Ament Z, West JA, Stanley E, Ashmore T, Roberts LD, Wright J, Nicholls AW, Griffin JL. Ament Z, et al. Among authors: Nicholls AW. Free Radic Biol Med. 2016 Jun;95:357-68. doi: 10.1016/j.freeradbiomed.2015.11.033. Epub 2015 Nov 30. Free Radic Biol Med. 2016. PMID: 26654758 Free PMC article.
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