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Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development.
Sznurkowska MK, Hannezo E, Azzarelli R, Rulands S, Nestorowa S, Hindley CJ, Nichols J, Göttgens B, Huch M, Philpott A, Simons BD. Sznurkowska MK, et al. Dev Cell. 2018 Aug 6;46(3):360-375.e5. doi: 10.1016/j.devcel.2018.06.028. Epub 2018 Jul 26. Dev Cell. 2018. PMID: 30057275 Free PMC article.
Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation.
Mohammed H, Hernando-Herraez I, Savino A, Scialdone A, Macaulay I, Mulas C, Chandra T, Voet T, Dean W, Nichols J, Marioni JC, Reik W. Mohammed H, et al. Cell Rep. 2017 Aug 1;20(5):1215-1228. doi: 10.1016/j.celrep.2017.07.009. Cell Rep. 2017. PMID: 28768204 Free PMC article.
The transcriptional and epigenomic foundations of ground state pluripotency.
Marks H, Kalkan T, Menafra R, Denissov S, Jones K, Hofemeister H, Nichols J, Kranz A, Stewart AF, Smith A, Stunnenberg HG. Marks H, et al. Cell. 2012 Apr 27;149(3):590-604. doi: 10.1016/j.cell.2012.03.026. Cell. 2012. PMID: 22541430 Free PMC article.
The germ cell determinant Blimp1 is not required for derivation of pluripotent stem cells.
Bao S, Leitch HG, Gillich A, Nichols J, Tang F, Kim S, Lee C, Zwaka T, Li X, Surani MA. Bao S, et al. Cell Stem Cell. 2012 Jul 6;11(1):110-7. doi: 10.1016/j.stem.2012.02.023. Cell Stem Cell. 2012. PMID: 22770244 Free PMC article.
Resetting transcription factor control circuitry toward ground-state pluripotency in human.
Takashima Y, Guo G, Loos R, Nichols J, Ficz G, Krueger F, Oxley D, Santos F, Clarke J, Mansfield W, Reik W, Bertone P, Smith A. Takashima Y, et al. Cell. 2014 Sep 11;158(6):1254-1269. doi: 10.1016/j.cell.2014.08.029. Cell. 2014. PMID: 25215486 Free PMC article.
The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis.
Nascimento EM, Cox CL, MacArthur S, Hussain S, Trotter M, Blanco S, Suraj M, Nichols J, Kübler B, Benitah SA, Hendrich B, Odom DT, Frye M. Nascimento EM, et al. Nat Cell Biol. 2011 Nov 20;13(12):1395-405. doi: 10.1038/ncb2385. Nat Cell Biol. 2011. PMID: 22101514 Free PMC article.
LIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease.
Griffiths DS, Li J, Dawson MA, Trotter MW, Cheng YH, Smith AM, Mansfield W, Liu P, Kouzarides T, Nichols J, Bannister AJ, Green AR, Göttgens B. Griffiths DS, et al. Nat Cell Biol. 2011 Jan;13(1):13-21. doi: 10.1038/ncb2135. Epub 2010 Dec 12. Nat Cell Biol. 2011. PMID: 21151131 Free PMC article.
The ground state of embryonic stem cell self-renewal.
Ying QL, Wray J, Nichols J, Batlle-Morera L, Doble B, Woodgett J, Cohen P, Smith A. Ying QL, et al. Nature. 2008 May 22;453(7194):519-23. doi: 10.1038/nature06968. Nature. 2008. PMID: 18497825 Free PMC article.
Parameters influencing derivation of embryonic stem cells from murine embryos.
Batlle-Morera L, Smith A, Nichols J. Batlle-Morera L, et al. Genesis. 2008 Dec;46(12):758-67. doi: 10.1002/dvg.20442. Genesis. 2008. PMID: 18837461
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