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NBD-labeled phosphatidylcholine and phosphatidylethanolamine are internalized by transbilayer transport across the yeast plasma membrane.
Grant AM, Hanson PK, Malone L, Nichols JW. Grant AM, et al. Among authors: nichols jw. Traffic. 2001 Jan;2(1):37-50. doi: 10.1034/j.1600-0854.2001.020106.x. Traffic. 2001. PMID: 11208167
Spontaneous, intervesicular transfer rates of fluorescent, acyl chain-labeled phosphatidylcholine analogs.
Elvington SM, Nichols JW. Elvington SM, et al. Among authors: nichols jw. Biochim Biophys Acta. 2007 Mar;1768(3):502-8. doi: 10.1016/j.bbamem.2006.11.013. Epub 2006 Dec 5. Biochim Biophys Acta. 2007. PMID: 17198675 Free PMC article.
Fluorescent, acyl chain-labeled phosphatidylcholine analogs reveal novel transport pathways across the plasma membrane of yeast.
Elvington SM, Bu F, Nichols JW. Elvington SM, et al. Among authors: nichols jw. J Biol Chem. 2005 Dec 9;280(49):40957-64. doi: 10.1074/jbc.M507926200. Epub 2005 Oct 4. J Biol Chem. 2005. PMID: 16204231
Lem3p is essential for the uptake and potency of alkylphosphocholine drugs, edelfosine and miltefosine.
Hanson PK, Malone L, Birchmore JL, Nichols JW. Hanson PK, et al. Among authors: nichols jw. J Biol Chem. 2003 Sep 19;278(38):36041-50. doi: 10.1074/jbc.M305263200. Epub 2003 Jul 3. J Biol Chem. 2003. PMID: 12842877
Internalization and trafficking of fluorescent-labeled phospholipids in yeast.
Nichols JW. Nichols JW. Semin Cell Dev Biol. 2002 Jun;13(3):179-84. doi: 10.1016/s1084-9521(02)00046-0. Semin Cell Dev Biol. 2002. PMID: 12137738 Review.
NBD-labeled phosphatidylcholine enters the yeast vacuole via the pre-vacuolar compartment.
Hanson PK, Grant AM, Nichols JW. Hanson PK, et al. Among authors: nichols jw. J Cell Sci. 2002 Jul 1;115(Pt 13):2725-33. J Cell Sci. 2002. PMID: 12077363
The proton electrochemical gradient across the plasma membrane of yeast is necessary for phospholipid flip.
Stevens HC, Nichols JW. Stevens HC, et al. Among authors: nichols jw. J Biol Chem. 2007 Jun 15;282(24):17563-7. doi: 10.1074/jbc.M700454200. Epub 2007 Apr 23. J Biol Chem. 2007. PMID: 17452326
Saccharomyces cerevisiae Npc2p is a functionally conserved homologue of the human Niemann-Pick disease type C 2 protein, hNPC2.
Berger AC, Vanderford TH, Gernert KM, Nichols JW, Faundez V, Corbett AH. Berger AC, et al. Among authors: nichols jw. Eukaryot Cell. 2005 Nov;4(11):1851-62. doi: 10.1128/EC.4.11.1851-1862.2005. Eukaryot Cell. 2005. PMID: 16278452 Free PMC article.
The putative aminophospholipid translocases, DNF1 and DNF2, are not required for 7-nitrobenz-2-oxa-1,3-diazol-4-yl-phosphatidylserine flip across the plasma membrane of Saccharomyces cerevisiae.
Stevens HC, Malone L, Nichols JW. Stevens HC, et al. Among authors: nichols jw. J Biol Chem. 2008 Dec 12;283(50):35060-9. doi: 10.1074/jbc.M802379200. Epub 2008 Oct 19. J Biol Chem. 2008. PMID: 18931395 Free PMC article.
Dithionite quenching rate measurement of the inside-outside membrane bilayer distribution of 7-nitrobenz-2-oxa-1,3-diazol-4-yl-labeled phospholipids.
Angeletti C, Nichols JW. Angeletti C, et al. Among authors: nichols jw. Biochemistry. 1998 Oct 27;37(43):15114-9. doi: 10.1021/bi9810104. Biochemistry. 1998. PMID: 9790674
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