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Defining stem cell dynamics in models of intestinal tumor initiation.
Vermeulen L, Morrissey E, van der Heijden M, Nicholson AM, Sottoriva A, Buczacki S, Kemp R, Tavaré S, Winton DJ. Vermeulen L, et al. Among authors: nicholson am. Science. 2013 Nov 22;342(6161):995-8. doi: 10.1126/science.1243148. Science. 2013. PMID: 24264992
Bcl-2 is a critical mediator of intestinal transformation.
van der Heijden M, Zimberlin CD, Nicholson AM, Colak S, Kemp R, Meijer SL, Medema JP, Greten FR, Jansen M, Winton DJ, Vermeulen L. van der Heijden M, et al. Among authors: nicholson am. Nat Commun. 2016 Mar 9;7:10916. doi: 10.1038/ncomms10916. Nat Commun. 2016. PMID: 26956214 Free PMC article.
Fixation and Spread of Somatic Mutations in Adult Human Colonic Epithelium.
Nicholson AM, Olpe C, Hoyle A, Thorsen AS, Rus T, Colombé M, Brunton-Sim R, Kemp R, Marks K, Quirke P, Malhotra S, Ten Hoopen R, Ibrahim A, Lindskog C, Myers MB, Parsons B, Tavaré S, Wilkinson M, Morrissey E, Winton DJ. Nicholson AM, et al. Cell Stem Cell. 2018 Jun 1;22(6):909-918.e8. doi: 10.1016/j.stem.2018.04.020. Epub 2018 May 17. Cell Stem Cell. 2018. PMID: 29779891 Free PMC article.
Field cancerization in the intestinal epithelium of patients with Crohn's ileocolitis.
Galandiuk S, Rodriguez-Justo M, Jeffery R, Nicholson AM, Cheng Y, Oukrif D, Elia G, Leedham SJ, McDonald SA, Wright NA, Graham TA. Galandiuk S, et al. Among authors: nicholson am. Gastroenterology. 2012 Apr;142(4):855-864.e8. doi: 10.1053/j.gastro.2011.12.004. Epub 2011 Dec 13. Gastroenterology. 2012. PMID: 22178590 Free PMC article.
The stem cell organisation, and the proliferative and gene expression profile of Barrett's epithelium, replicates pyloric-type gastric glands.
Lavery DL, Nicholson AM, Poulsom R, Jeffery R, Hussain A, Gay LJ, Jankowski JA, Zeki SS, Barr H, Harrison R, Going J, Kadirkamanathan S, Davis P, Underwood T, Novelli MR, Rodriguez-Justo M, Shepherd N, Jansen M, Wright NA, McDonald SA. Lavery DL, et al. Among authors: nicholson am. Gut. 2014 Dec;63(12):1854-63. doi: 10.1136/gutjnl-2013-306508. Epub 2014 Feb 18. Gut. 2014. PMID: 24550372 Free PMC article.
81 results