Nicholson DW - Search Results

1

ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis.

Nicholson DW. Nicholson DW. Nat Biotechnol. 1996 Mar;14(3):297-301. doi: 10.1038/nbt0396-297. Nat Biotechnol. 1996. PMID: 9630889 Review.

2

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome.

Marsden VS, O'Connor L, O'Reilly LA, Silke J, Metcalf D, Ekert PG, Huang DC, Cecconi F, Kuida K, Tomaselli KJ, Roy S, Nicholson DW, Vaux DL, Bouillet P, Adams JM, Strasser A. Marsden VS, et al. Among authors: nicholson dw. Nature. 2002 Oct 10;419(6907):634-7. doi: 10.1038/nature01101. Epub 2002 Sep 25. Nature. 2002. PMID: 12374983

3

Apoptosis. Baiting death inhibitors.

Nicholson DW. Nicholson DW. Nature. 2001 Mar 1;410(6824):33-4. doi: 10.1038/35065201. Nature. 2001. PMID: 11242030 No abstract available.

4

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract.

Wellington CL, Ellerby LM, Hackam AS, Margolis RL, Trifiro MA, Singaraja R, McCutcheon K, Salvesen GS, Propp SS, Bromm M, Rowland KJ, Zhang T, Rasper D, Roy S, Thornberry N, Pinsky L, Kakizuka A, Ross CA, Nicholson DW, Bredesen DE, Hayden MR. Wellington CL, et al. Among authors: nicholson dw. J Biol Chem. 1998 Apr 10;273(15):9158-67. doi: 10.1074/jbc.273.15.9158. J Biol Chem. 1998. PMID: 9535906

5

Substrate cleavage by caspases generates protein fragments with Smac/Diablo-like activities.

Hell K, Saleh M, Crescenzo GD, O'Connor-McCourt MD, Nicholson DW. Hell K, et al. Among authors: nicholson dw. Cell Death Differ. 2003 Nov;10(11):1234-9. doi: 10.1038/sj.cdd.4401298. Cell Death Differ. 2003. PMID: 14576775

6

Neuroprotection by the inhibition of apoptosis.

Robertson GS, Crocker SJ, Nicholson DW, Schulz JB. Robertson GS, et al. Among authors: nicholson dw. Brain Pathol. 2000 Apr;10(2):283-92. doi: 10.1111/j.1750-3639.2000.tb00262.x. Brain Pathol. 2000. PMID: 10764048 Review.

7

Inhibition of human caspases by peptide-based and macromolecular inhibitors.

Garcia-Calvo M, Peterson EP, Leiting B, Ruel R, Nicholson DW, Thornberry NA. Garcia-Calvo M, et al. Among authors: nicholson dw. J Biol Chem. 1998 Dec 4;273(49):32608-13. doi: 10.1074/jbc.273.49.32608. J Biol Chem. 1998. PMID: 9829999

8

Control of apoptosis by proteases.

Thornberry NA, Rosen A, Nicholson DW. Thornberry NA, et al. Among authors: nicholson dw. Adv Pharmacol. 1997;41:155-77. doi: 10.1016/s1054-3589(08)61058-3. Adv Pharmacol. 1997. PMID: 9204145 Review. No abstract available.

9

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis.

Thornberry NA, Rano TA, Peterson EP, Rasper DM, Timkey T, Garcia-Calvo M, Houtzager VM, Nordstrom PA, Roy S, Vaillancourt JP, Chapman KT, Nicholson DW. Thornberry NA, et al. Among authors: nicholson dw. J Biol Chem. 1997 Jul 18;272(29):17907-11. doi: 10.1074/jbc.272.29.17907. J Biol Chem. 1997. PMID: 9218414

10

Catalytic activity of caspase-3 is required for its degradation: stabilization of the active complex by synthetic inhibitors.

Tawa P, Hell K, Giroux A, Grimm E, Han Y, Nicholson DW, Xanthoudakis S. Tawa P, et al. Among authors: nicholson dw. Cell Death Differ. 2004 Apr;11(4):439-47. doi: 10.1038/sj.cdd.4401360. Cell Death Differ. 2004. PMID: 14713960

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