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Apoptosis. Baiting death inhibitors.
Nicholson DW. Nicholson DW. Nature. 2001 Mar 1;410(6824):33-4. doi: 10.1038/35065201. Nature. 2001. PMID: 11242030 No abstract available.
Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract.
Wellington CL, Ellerby LM, Hackam AS, Margolis RL, Trifiro MA, Singaraja R, McCutcheon K, Salvesen GS, Propp SS, Bromm M, Rowland KJ, Zhang T, Rasper D, Roy S, Thornberry N, Pinsky L, Kakizuka A, Ross CA, Nicholson DW, Bredesen DE, Hayden MR. Wellington CL, et al. Among authors: nicholson dw. J Biol Chem. 1998 Apr 10;273(15):9158-67. doi: 10.1074/jbc.273.15.9158. J Biol Chem. 1998. PMID: 9535906
Neuroprotection by the inhibition of apoptosis.
Robertson GS, Crocker SJ, Nicholson DW, Schulz JB. Robertson GS, et al. Among authors: nicholson dw. Brain Pathol. 2000 Apr;10(2):283-92. doi: 10.1111/j.1750-3639.2000.tb00262.x. Brain Pathol. 2000. PMID: 10764048 Review.
Control of apoptosis by proteases.
Thornberry NA, Rosen A, Nicholson DW. Thornberry NA, et al. Among authors: nicholson dw. Adv Pharmacol. 1997;41:155-77. doi: 10.1016/s1054-3589(08)61058-3. Adv Pharmacol. 1997. PMID: 9204145 Review. No abstract available.
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis.
Thornberry NA, Rano TA, Peterson EP, Rasper DM, Timkey T, Garcia-Calvo M, Houtzager VM, Nordstrom PA, Roy S, Vaillancourt JP, Chapman KT, Nicholson DW. Thornberry NA, et al. Among authors: nicholson dw. J Biol Chem. 1997 Jul 18;272(29):17907-11. doi: 10.1074/jbc.272.29.17907. J Biol Chem. 1997. PMID: 9218414
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