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NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats.
Nicholls AW, Mortishire-Smith RJ, Nicholson JK. Nicholls AW, et al. Among authors: nicholson jk. Chem Res Toxicol. 2003 Nov;16(11):1395-404. doi: 10.1021/tx0340293. Chem Res Toxicol. 2003. PMID: 14615964
Metabolic trajectory characterisation of xenobiotic-induced hepatotoxic lesions using statistical batch processing of NMR data.
Azmi J, Griffin JL, Antti H, Shore RF, Johansson E, Nicholson JK, Holmes E. Azmi J, et al. Among authors: nicholson jk. Analyst. 2002 Feb;127(2):271-6. doi: 10.1039/b109430k. Analyst. 2002. PMID: 11913873
The comparison of plasma deproteinization methods for the detection of low-molecular-weight metabolites by (1)H nuclear magnetic resonance spectroscopy.
Daykin CA, Foxall PJ, Connor SC, Lindon JC, Nicholson JK. Daykin CA, et al. Among authors: nicholson jk. Anal Biochem. 2002 May 15;304(2):220-30. doi: 10.1006/abio.2002.5637. Anal Biochem. 2002. PMID: 12009699
Earthworm species of the genus Eisenia can be phenotypically differentiated by metabolic profiling.
Bundy JG, Spurgeon DJ, Svendsen C, Hankard PK, Osborn D, Lindon JC, Nicholson JK. Bundy JG, et al. Among authors: nicholson jk. FEBS Lett. 2002 Jun 19;521(1-3):115-20. doi: 10.1016/s0014-5793(02)02854-5. FEBS Lett. 2002. PMID: 12067738
Metabolic profiling of rodent biological fluids via 1H NMR spectroscopy using a 1 mm microlitre probe.
Griffin JL, Nicholls AW, Keun HC, Mortishire-Smith RJ, Nicholson JK, Kuehn T. Griffin JL, et al. Among authors: nicholson jk. Analyst. 2002 May;127(5):582-4. doi: 10.1039/b201207c. Analyst. 2002. PMID: 12081031
NMR and pattern recognition studies on liver extracts and intact livers from rats treated with alpha-naphthylisothiocyanate.
Waters NJ, Holmes E, Waterfield CJ, Farrant RD, Nicholson JK. Waters NJ, et al. Among authors: nicholson jk. Biochem Pharmacol. 2002 Jul 1;64(1):67-77. doi: 10.1016/s0006-2952(02)01016-x. Biochem Pharmacol. 2002. PMID: 12106607
Metabonomics: a platform for studying drug toxicity and gene function.
Nicholson JK, Connelly J, Lindon JC, Holmes E. Nicholson JK, et al. Nat Rev Drug Discov. 2002 Feb;1(2):153-61. doi: 10.1038/nrd728. Nat Rev Drug Discov. 2002. PMID: 12120097 Review.
Metabonomic assessment of toxicity of 4-fluoroaniline, 3,5-difluoroaniline and 2-fluoro-4-methylaniline to the earthworm Eisenia veneta (Rosa): identification of new endogenous biomarkers.
Bundy JG, Lenz EM, Bailey NJ, Gavaghan CL, Svendsen C, Spurgeon D, Hankard PK, Osborn D, Weeks JM, Trauger SA, Speir P, Sanders I, Lindon JC, Nicholson JK, Tang H. Bundy JG, et al. Among authors: nicholson jk. Environ Toxicol Chem. 2002 Sep;21(9):1966-72. Environ Toxicol Chem. 2002. PMID: 12206438
Multi-component metabolic classification of commercial feverfew preparations via high-field 1H-NMR spectroscopy and chemometrics.
Bailey NJ, Sampson J, Hylands PJ, Nicholson JK, Holmes E. Bailey NJ, et al. Among authors: nicholson jk. Planta Med. 2002 Aug;68(8):734-8. doi: 10.1055/s-2002-33793. Planta Med. 2002. PMID: 12221598
NMR-based metabonomic studies on the biochemical effects of commonly used drug carrier vehicles in the rat.
Beckwith-Hall BM, Holmes E, Lindon JC, Gounarides J, Vickers A, Shapiro M, Nicholson JK. Beckwith-Hall BM, et al. Among authors: nicholson jk. Chem Res Toxicol. 2002 Sep;15(9):1136-41. doi: 10.1021/tx020020+. Chem Res Toxicol. 2002. PMID: 12230406
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