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2018 1
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86 results

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Page 1
Atherosclerosis evaluation and cardiovascular risk estimation using coronary computed tomography angiography.
Nurmohamed NS, van Rosendael AR, Danad I, Ngo-Metzger Q, Taub PR, Ray KK, Figtree G, Bonaca MP, Hsia J, Rodriguez F, Sandhu AT, Nieman K, Earls JP, Hoffmann U, Bax JJ, Min JK, Maron DJ, Bhatt DL. Nurmohamed NS, et al. Eur Heart J. 2024 May 27;45(20):1783-1800. doi: 10.1093/eurheartj/ehae190. Eur Heart J. 2024. PMID: 38606889 Free PMC article. Review.
Clinical risk scores based on traditional risk factors of atherosclerosis correlate imprecisely to an individual's complex pathophysiological predisposition to atherosclerosis and provide limited accuracy for predicting major adverse cardiovascular events (MACE). Over the …
Clinical risk scores based on traditional risk factors of atherosclerosis correlate imprecisely to an individual's complex pathophysiologica …
Proteomics and lipidomics in atherosclerotic cardiovascular disease risk prediction.
Nurmohamed NS, Kraaijenhof JM, Mayr M, Nicholls SJ, Koenig W, Catapano AL, Stroes ESG. Nurmohamed NS, et al. Eur Heart J. 2023 May 7;44(18):1594-1607. doi: 10.1093/eurheartj/ehad161. Eur Heart J. 2023. PMID: 36988179 Free PMC article.
Given the limited accuracy of clinically used risk scores such as the Systematic COronary Risk Evaluation 2 system and the Second Manifestations of ARTerial disease 2 risk scores, novel risk algorithms determining an individual's susceptibility of future incident or recurr …
Given the limited accuracy of clinically used risk scores such as the Systematic COronary Risk Evaluation 2 system and the Second Man …
Atherosclerosis quantification and cardiovascular risk: the ISCHEMIA trial.
Nurmohamed NS, Min JK, Anthopolos R, Reynolds HR, Earls JP, Crabtree T, Mancini GBJ, Leipsic J, Budoff MJ, Hague CJ, O'Brien SM, Stone GW, Berger JS, Donnino R, Sidhu MS, Newman JD, Boden WE, Chaitman BR, Stone PH, Bangalore S, Spertus JA, Mark DB, Shaw LJ, Hochman JS, Maron DJ. Nurmohamed NS, et al. Eur Heart J. 2024 Sep 29;45(36):3735-3747. doi: 10.1093/eurheartj/ehae471. Eur Heart J. 2024. PMID: 39101625 Free PMC article. Clinical Trial.
Multivariable Cox regression was used to examine the association between baseline risk factors (age, sex, smoking, diabetes, hypertension, ejection fraction, prior coronary disease, estimated glomerular filtration rate, and statin use), number of diseased vessels, atherosclerotic …
Multivariable Cox regression was used to examine the association between baseline risk factors (age, sex, smoking, diabetes, hypertension, e …
Association of Lipoprotein(a) With Atherosclerotic Plaque Progression.
Kaiser Y, Daghem M, Tzolos E, Meah MN, Doris MK, Moss AJ, Kwiecinski J, Kroon J, Nurmohamed NS, van der Harst P, Adamson PD, Williams MC, Dey D, Newby DE, Stroes ESG, Zheng KH, Dweck MR. Kaiser Y, et al. Among authors: nurmohamed ns. J Am Coll Cardiol. 2022 Jan 25;79(3):223-233. doi: 10.1016/j.jacc.2021.10.044. J Am Coll Cardiol. 2022. PMID: 35057907 Free PMC article.
The relationship of Lp(a) with plaque progression was assessed using linear regression analysis, adjusting for body mass index, segment involvement score, and ASSIGN score (a Scottish cardiovascular risk score comprised of age, sex, smoking, blood pressure, total and high- …
The relationship of Lp(a) with plaque progression was assessed using linear regression analysis, adjusting for body mass index, segment invo …
New and Emerging Therapies for Reduction of LDL-Cholesterol and Apolipoprotein B: JACC Focus Seminar 1/4.
Nurmohamed NS, Navar AM, Kastelein JJP. Nurmohamed NS, et al. J Am Coll Cardiol. 2021 Mar 30;77(12):1564-1575. doi: 10.1016/j.jacc.2020.11.079. J Am Coll Cardiol. 2021. PMID: 33766264 Free article. Review.
Adding to the foundation of statins, ezetimibe and proprotein convertase subtilisin-kexin type 9 inhibitors (PCSK9i), novel, emerging low-density lipoprotein cholesterol (LDL-C)-lowering therapies are under development for the prevention of cardiovascular disease. Inclisir …
Adding to the foundation of statins, ezetimibe and proprotein convertase subtilisin-kexin type 9 inhibitors (PCSK9i), novel, emerging low-de …
Lipoprotein(a) and Long-Term Plaque Progression, Low-Density Plaque, and Pericoronary Inflammation.
Nurmohamed NS, Gaillard EL, Malkasian S, de Groot RJ, Ibrahim S, Bom MJ, Kaiser Y, Earls JP, Min JK, Kroon J, Planken RN, Danad I, van Rosendael AR, Choi AD, Stroes ESG, Knaapen P. Nurmohamed NS, et al. JAMA Cardiol. 2024 Sep 1;9(9):826-834. doi: 10.1001/jamacardio.2024.1874. JAMA Cardiol. 2024. PMID: 39018040 Free PMC article.
IMPORTANCE: Lipoprotein(a) (Lp[a]) is a causal risk factor for cardiovascular disease; however, long-term effects on coronary atherosclerotic plaque phenotype, high-risk plaque formation, and pericoronary adipose tissue inflammation remain unknown. ...
IMPORTANCE: Lipoprotein(a) (Lp[a]) is a causal risk factor for cardiovascular disease; however, long-term effects on coronary atheros …
First myocardial infarction: risk factors, symptoms, and medical therapy.
Nurmohamed NS, Ngo-Metzger Q, Taub PR, Ray KK, Figtree GA, Bonaca MP, Hsia JA, Angadageri S, Earls JP, Rodriguez F, Sandhu AT, Min JK, Hoffmann U, Maron DJ, Bhatt DL. Nurmohamed NS, et al. Eur Heart J. 2025 Oct 7;46(38):3762-3772. doi: 10.1093/eurheartj/ehaf390. Eur Heart J. 2025. PMID: 40605456 Free PMC article.
BACKGROUND AND AIMS: Despite the implementation of clinical risk algorithms based on traditional risk factors, the global burden of atherosclerotic cardiovascular disease has continued to rise over the past decades. There are few real-world data on prevalence of both sympt …
BACKGROUND AND AIMS: Despite the implementation of clinical risk algorithms based on traditional risk factors, the global burden of atherosc …
AI-Guided Quantitative Plaque Staging Predicts Long-Term Cardiovascular Outcomes in Patients at Risk for Atherosclerotic CVD.
Nurmohamed NS, Bom MJ, Jukema RA, de Groot RJ, Driessen RS, van Diemen PA, de Winter RW, Gaillard EL, Sprengers RW, Stroes ESG, Min JK, Earls JP, Cardoso R, Blankstein R, Danad I, Choi AD, Knaapen P. Nurmohamed NS, et al. JACC Cardiovasc Imaging. 2024 Mar;17(3):269-280. doi: 10.1016/j.jcmg.2023.05.020. Epub 2023 Jul 19. JACC Cardiovasc Imaging. 2024. PMID: 37480907 Free article.
CCTA scans were analyzed with AI-QCT and plaque burden was classified with a plaque staging system (stage 0: 0% percentage atheroma volume [PAV]; stage 1: >0%-5% PAV; stage 2: >5%-15% PAV; stage 3: >15% PAV). ...Furthermore, AI-QCT achieved an improved area under …
CCTA scans were analyzed with AI-QCT and plaque burden was classified with a plaque staging system (stage 0: 0% percentage atheroma v …
Worldwide Radiation Dose in Coronary Artery Disease Diagnostic Imaging.
Einstein AJ, Williams MC, Weir-McCall JR, Shaw LJ, Karthikeyan G, Better N, Vitola JV, Cerci RJ, Dorbala S, Bouyoucef SE, Choi AD, Pontone G, Ozkan E, Yang LD, Bremner L, Castillo M, Cohen YA, Malkovskiy E, Ayoola I, Veduta A, Yurystovskyi D, Pynda Y, Pascual TNB, Knoll P, Dondi M, Paez D; INCAPS 4 Investigators Group. Einstein AJ, et al. JAMA. 2026 Apr 7;335(13):1148-1158. doi: 10.1001/jama.2026.0703. JAMA. 2026. PMID: 41739468
Development and Validation of a Quantitative Coronary CT Angiography Model for Diagnosis of Vessel-Specific Coronary Ischemia.
Nurmohamed NS, Danad I, Jukema RA, de Winter RW, de Groot RJ, Driessen RS, Bom MJ, van Diemen P, Pontone G, Andreini D, Chang HJ, Katz RJ, Stroes ESG, Wang H, Chan C, Crabtree T, Aquino M, Min JK, Earls JP, Bax JJ, Choi AD, Knaapen P, van Rosendael AR; CREDENCE and PACIFIC-1 Investigators. Nurmohamed NS, et al. JACC Cardiovasc Imaging. 2024 Aug;17(8):894-906. doi: 10.1016/j.jcmg.2024.01.007. Epub 2024 Mar 13. JACC Cardiovasc Imaging. 2024. PMID: 38483420 Free article.
OBJECTIVES: This study aimed to derive and validate an artificial intelligence-guided quantitative coronary computed tomography angiography (AI-QCT) model for the diagnosis of coronary ischemia that integrates atherosclerosis and vascular morphology measures (AI-QCT(ISCHEMIA)) an …
OBJECTIVES: This study aimed to derive and validate an artificial intelligence-guided quantitative coronary computed tomography angiography …
86 results