Nickels ML - Search Results

1

Discovery of Furanone-Based Radiopharmaceuticals for Diagnostic Targeting of COX-1 in Ovarian Cancer.

Uddin MJ, Wilson AJ, Crews BC, Malerba P, Uddin MI, Kingsley PJ, Ghebreselasie K, Daniel CK, Nickels ML, Tantawy MN, Jashim E, Manning HC, Khabele D, Marnett LJ. Uddin MJ, et al. Among authors: nickels ml. ACS Omega. 2019 May 31;4(5):9251-9261. doi: 10.1021/acsomega.9b01093. Epub 2019 May 24. ACS Omega. 2019. PMID: 31172046 Free PMC article.

2

PET radiotracer [¹⁸F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: preliminary investigation.

Perrone MG, Malerba P, Uddin J, Vitale P, Panella A, Crews BC, Daniel CK, Ghebreselasie K, Nickels M, Tantawy MN, Manning HC, Marnett LJ, Scilimati A. Perrone MG, et al. Eur J Med Chem. 2014 Jun 10;80:562-568. doi: 10.1016/j.ejmech.2014.04.074. Epub 2014 Apr 29. Eur J Med Chem. 2014. PMID: 24832612 Free PMC article.

3

The Current Role of Microfluidics in Radiofluorination Chemistry.

Knapp KA, Nickels ML, Manning HC. Knapp KA, et al. Among authors: nickels ml. Mol Imaging Biol. 2020 Jun;22(3):463-475. doi: 10.1007/s11307-019-01414-6. Mol Imaging Biol. 2020. PMID: 31485889 Review.

4

Convergent synthesis and evaluation of (18)F-labeled azulenic COX2 probes for cancer imaging.

Nolting DD, Nickels M, Tantawy MN, Yu JY, Xie J, Peterson TE, Crews BC, Marnett L, Gore JC, Pham W. Nolting DD, et al. Front Oncol. 2013 Jan 3;2:207. doi: 10.3389/fonc.2012.00207. eCollection 2012. Front Oncol. 2013. PMID: 23316477 Free PMC article.

5

Preclinical Evaluation of 4-[18F]Fluoroglutamine PET to Assess ASCT2 Expression in Lung Cancer.

Hassanein M, Hight MR, Buck JR, Tantawy MN, Nickels ML, Hoeksema MD, Harris BK, Boyd K, Massion PP, Manning HC. Hassanein M, et al. Among authors: nickels ml. Mol Imaging Biol. 2016 Feb;18(1):18-23. doi: 10.1007/s11307-015-0862-4. Mol Imaging Biol. 2016. PMID: 25971659 Free PMC article.

6

Preclinical Evaluation of a Novel TSPO PET Ligand 2-(7-Butyl-2-(4-(2-[¹⁸F]Fluoroethoxy)phenyl)-5-Methylpyrazolo[1,5-a]Pyrimidin-3-yl)-N,N-Diethylacetamide (¹⁸F-VUIIS1018A) to Image Glioma.

Tang D, Li J, Nickels ML, Huang G, Cohen AS, Manning HC. Tang D, et al. Among authors: nickels ml. Mol Imaging Biol. 2019 Feb;21(1):113-121. doi: 10.1007/s11307-018-1198-7. Mol Imaging Biol. 2019. PMID: 29869061 Free PMC article.

7

Preclinical imaging evaluation of novel TSPO-PET ligand 2-(5,7-Diethyl-2-(4-(2-[(18)F]fluoroethoxy)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamide ([ (18)F]VUIIS1008) in glioma.

Tang D, Nickels ML, Tantawy MN, Buck JR, Manning HC. Tang D, et al. Among authors: nickels ml. Mol Imaging Biol. 2014 Dec;16(6):813-20. doi: 10.1007/s11307-014-0743-2. Mol Imaging Biol. 2014. PMID: 24845529 Free PMC article.

8

Facile synthesis of SSR180575 and discovery of 7-chloro-N,N,5-trimethyl-4-oxo-3(6-[(18)F]fluoropyridin-2-yl)-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide, a potent pyridazinoindole ligand for PET imaging of TSPO in cancer.

Cheung YY, Nickels ML, Tang D, Buck JR, Manning HC. Cheung YY, et al. Among authors: nickels ml. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4466-4471. doi: 10.1016/j.bmcl.2014.07.091. Epub 2014 Aug 8. Bioorg Med Chem Lett. 2014. PMID: 25172419 Free PMC article.

9

New structure-activity relationships of N-acetamide substituted pyrazolopyrimidines as pharmacological ligands of TSPO.

Li J, Schulte ML, Nickels ML, Manning HC. Li J, et al. Among authors: nickels ml. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3472-7. doi: 10.1016/j.bmcl.2016.06.041. Epub 2016 Jun 16. Bioorg Med Chem Lett. 2016. PMID: 27353534 Free PMC article.

10

A simple microfluidic platform for rapid and efficient production of the radiotracer [¹⁸F]fallypride.

Zhang X, Liu F, Knapp KA, Nickels ML, Manning HC, Bellan LM. Zhang X, et al. Among authors: nickels ml. Lab Chip. 2018 May 1;18(9):1369-1377. doi: 10.1039/c8lc00167g. Lab Chip. 2018. PMID: 29658049

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