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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1950 1
1952 1
1960 3
1961 10
1962 6
1963 14
1964 14
1965 13
1966 6
1967 9
1968 5
1969 11
1970 12
1971 10
1972 10
1973 20
1974 13
1975 21
1976 13
1977 11
1978 13
1979 15
1980 13
1981 15
1982 17
1983 9
1984 13
1985 9
1986 10
1987 15
1988 10
1989 11
1990 10
1991 16
1992 16
1993 4
1994 6
1995 7
1996 13
1997 9
1998 11
1999 7
2000 9
2001 8
2002 12
2003 8
2004 24
2005 10
2006 13
2007 16
2008 8
2009 11
2010 16
2011 26
2012 32
2013 37
2014 43
2015 50
2016 69
2017 69
2018 90
2019 83
2020 79
2021 125
2022 104
2023 18
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1,322 results
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Page 1
Niclosamide: Beyond an antihelminthic drug.
Chen W, Mook RA Jr, Premont RT, Wang J. Chen W, et al. Cell Signal. 2018 Jan;41:89-96. doi: 10.1016/j.cellsig.2017.04.001. Epub 2017 Apr 4. Cell Signal. 2018. PMID: 28389414 Free PMC article. Review.
Niclosamide is an oral antihelminthic drug used to treat parasitic infections in millions of people worldwide. However recent studies have indicated that niclosamide may have broad clinical applications for the treatment of diseases other than those caused by parasi …
Niclosamide is an oral antihelminthic drug used to treat parasitic infections in millions of people worldwide. However recent studies …
Niclosamide-A promising treatment for COVID-19.
Singh S, Weiss A, Goodman J, Fisk M, Kulkarni S, Lu I, Gray J, Smith R, Sommer M, Cheriyan J. Singh S, et al. Br J Pharmacol. 2022 Jul;179(13):3250-3267. doi: 10.1111/bph.15843. Epub 2022 Apr 11. Br J Pharmacol. 2022. PMID: 35348204 Free PMC article. Review.
Here, we review the pharmacology and scientific rationale for repurposing niclosamide, an anti-helminth already in human use as a treatment for COVID-19. ...Finally, we give an overview of ongoing clinical trials investigating niclosamide as a promising candidate ag …
Here, we review the pharmacology and scientific rationale for repurposing niclosamide, an anti-helminth already in human use as a tre …
Niclosamide for Covid-19: bridging the gap.
Al-Kuraishy HM, Al-Gareeb AI, Alzahrani KJ, Alexiou A, Batiha GE. Al-Kuraishy HM, et al. Mol Biol Rep. 2021 Dec;48(12):8195-8202. doi: 10.1007/s11033-021-06770-7. Epub 2021 Oct 18. Mol Biol Rep. 2021. PMID: 34664162 Free PMC article. Review.
AIM/PURPOSE: Niclosamide (NCL) is an anthelminthic drug, which is widely used to treat various diseases due to its pleiotropic anti-inflammatory and antiviral activities. ...
AIM/PURPOSE: Niclosamide (NCL) is an anthelminthic drug, which is widely used to treat various diseases due to its pleiotropic anti-i …
Niclosamide as a Promising Therapeutic Player in Human Cancer and Other Diseases.
Wang Z, Ren J, Du J, Wang H, Liu J, Wang G. Wang Z, et al. Int J Mol Sci. 2022 Dec 17;23(24):16116. doi: 10.3390/ijms232416116. Int J Mol Sci. 2022. PMID: 36555754 Free PMC article. Review.
Niclosamide is an FDA-approved anthelmintic drug for the treatment of parasitic infections. ...Therefore, we systematically reviewed the pharmacological activities and therapeutic prospects of niclosamide in human disease and cancer and summarized the related molecu …
Niclosamide is an FDA-approved anthelmintic drug for the treatment of parasitic infections. ...Therefore, we systematically reviewed …
Niclosamide Ethanolamine Salt Alleviates Idiopathic Pulmonary Fibrosis by Modulating the PI3K-mTORC1 Pathway.
Pei X, Zheng F, Li Y, Lin Z, Han X, Feng Y, Tian Z, Ren D, Cao K, Li C. Pei X, et al. Cells. 2022 Jan 20;11(3):346. doi: 10.3390/cells11030346. Cells. 2022. PMID: 35159160 Free PMC article.
More signalling pathways, including the PI3K-Akt-mTOR and autophagy pathways, are involved in IPF pathogenesis. Niclosamide ethanolamine salt (NEN) is a highly effective multitarget small-molecule inhibitor reported in antitumor studies. ...
More signalling pathways, including the PI3K-Akt-mTOR and autophagy pathways, are involved in IPF pathogenesis. Niclosamide ethanolam …
Combination of niclosamide and current therapies to overcome resistance for cancer: New frontiers for an old drug.
Ren J, Wang B, Wu Q, Wang G. Ren J, et al. Biomed Pharmacother. 2022 Nov;155:113789. doi: 10.1016/j.biopha.2022.113789. Epub 2022 Oct 8. Biomed Pharmacother. 2022. PMID: 36271567 Free article. Review.
Niclosamide is a drug used to treat parasitic infections. Recent studies have shown that niclosamide may have a wide range of clinical applications and can be used to treat cancer and other diseases. ...This review summarizes the drug combination strategies and ther …
Niclosamide is a drug used to treat parasitic infections. Recent studies have shown that niclosamide may have a wide range of …
Niclosamide as a repurposing drug against Gram-positive bacterial infections.
Zhang W, Ran J, Shang L, Zhang L, Wang M, Fei C, Chen C, Gu F, Liu Y. Zhang W, et al. J Antimicrob Chemother. 2022 Nov 28;77(12):3312-3320. doi: 10.1093/jac/dkac319. J Antimicrob Chemother. 2022. PMID: 36173387
OBJECTIVES: Niclosamide is commonly used as an antiparasitic drug in veterinary clinics. ...Moreover, to study the antibacterial mechanism of niclosamide to Staphylococcus aureus. METHODS: A mouse topical infection model was established to detect the antibacterial a …
OBJECTIVES: Niclosamide is commonly used as an antiparasitic drug in veterinary clinics. ...Moreover, to study the antibacterial mech …
Niclosamide's potential direct targets in ovarian cancer†.
Sekulovski N, MacLean JA, Bheemireddy SR, Yu Z, Okuda H, Pru C, Plunkett KN, Matzuk M, Hayashi K. Sekulovski N, et al. Biol Reprod. 2021 Aug 3;105(2):403-412. doi: 10.1093/biolre/ioab071. Biol Reprod. 2021. PMID: 33855343 Free PMC article.
Recent evidence indicates that niclosamide is an anti-cancer compound that is able to inhibit several signaling pathways. ...The present study identifies key signal transduction mechanisms altered by niclosamide in ovarian cancer. Using affinity purification with a …
Recent evidence indicates that niclosamide is an anti-cancer compound that is able to inhibit several signaling pathways. ...The pres …
Niclosamide repositioning for treating cancer: Challenges and nano-based drug delivery opportunities.
Barbosa EJ, Löbenberg R, de Araujo GLB, Bou-Chacra NA. Barbosa EJ, et al. Eur J Pharm Biopharm. 2019 Aug;141:58-69. doi: 10.1016/j.ejpb.2019.05.004. Epub 2019 May 9. Eur J Pharm Biopharm. 2019. PMID: 31078739 Review.
Drug repositioning may be defined as a process when new biological effects for known drugs are identified, leading to recommendations for new therapeutic applications. Niclosamide, present in the Model List of Essential Medicines, from the World Health Organization, has be …
Drug repositioning may be defined as a process when new biological effects for known drugs are identified, leading to recommendations for ne …
Niclosamide, a Drug with Many (Re)purposes.
Kadri H, Lambourne OA, Mehellou Y. Kadri H, et al. ChemMedChem. 2018 Jun 6;13(11):1088-1091. doi: 10.1002/cmdc.201800100. Epub 2018 May 8. ChemMedChem. 2018. PMID: 29603892 Free PMC article.
Niclosamide is an anthelmintic drug that has been used for over 50 years mainly to treat tapeworm infections. ...In this highlight, we discuss the plethora of diseases that niclosamide has shown promise in treating....
Niclosamide is an anthelmintic drug that has been used for over 50 years mainly to treat tapeworm infections. ...In this highlight, w …
1,322 results