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Residue determination of two co-administered antibacterial agents--cephalexin and colistin--in calf tissues using high-performance liquid chromatography and microbiological methods.
Leroy P, Decolin D, Nicolas S, Archimbault P, Nicolas A. Leroy P, et al. Among authors: nicolas s, nicolas a. J Pharm Biomed Anal. 1989;7(12):1837-46. doi: 10.1016/0731-7085(89)80201-8. J Pharm Biomed Anal. 1989. PMID: 2490572
For cephalexin assay, tissue samples with cephradin as internal standard were homogenized in a 5% trichloroacetic acid solution and filtrates were injected onto a concentration precolumn filled with LiChroprep RP-18 (25-40 microns). A clean-up step was incorp …
For cephalexin assay, tissue samples with cephradin as internal standard were homogenized in a 5% trichloroacetic acid solution and f …
Clinical pharmacokinetics of D-penicillamine.
Netter P, Bannwarth B, Péré P, Nicolas A. Netter P, et al. Among authors: nicolas a. Clin Pharmacokinet. 1987 Nov;13(5):317-33. doi: 10.2165/00003088-198713050-00003. Clin Pharmacokinet. 1987. PMID: 3319347 Review.
The concentration in plasma then decreases rapidly, generally following a biphasic curve. When long term treatment is discontinued, there is a slow elimination phase lasting 4 to 6 days, which suggests that there is a 'deep compartment' or 'slow pool of the d …
The concentration in plasma then decreases rapidly, generally following a biphasic curve. When long term treatment is discontinued, t …
Determination of 2-mercaptopropionylglycine and its metabolite, 2-mercaptopropionic acid, in plasma by ion-pair reversed-phase high-performance liquid chromatography with post-column derivatization.
Leroy P, Nicolas A, Gavriloff C, Matt M, Netter P, Bannwarth B, Hercelin B, Mazza M. Leroy P, et al. Among authors: nicolas a. J Chromatogr. 1991 Mar 8;564(1):258-65. doi: 10.1016/0378-4347(91)80088-t. J Chromatogr. 1991. PMID: 1860918
A simple and fast high-performance liquid chromatographic method was developed for the simultaneous measurement of 2-mercaptopropionylglycine (Tiopronine) and its metabolite (2-mercaptopropionic acid) in human plasma after the administration of a pharmaceutical dosa
A simple and fast high-performance liquid chromatographic method was developed for the simultaneous measurement of 2-mercaptopropiony
Highly sensitive immuno-assays for the determination of cotinine in serum and saliva. Comparison between RIA and an avidin-biotin ELISA.
Benkirane S, Nicolas A, Galteau MM, Siest G. Benkirane S, et al. Among authors: nicolas a. Eur J Clin Chem Clin Biochem. 1991 Jun;29(6):405-10. doi: 10.1515/cclm.1991.29.6.405. Eur J Clin Chem Clin Biochem. 1991. PMID: 1912091
The comparative analysis of cotinine in 96 human sera revealed a good correlation between the two methods (r = 0.97) and a reliable discrimination between the populations of non-smokers and smokers. ...
The comparative analysis of cotinine in 96 human sera revealed a good correlation between the two methods (r = 0.97) and a rel …
Intracellular concentrations of fura-2 and fura-2/am in vascular smooth muscle cells following perfusion loading of fura-2/am in arterial segments.
Tran NN, Leroy P, Bellucci L, Robert A, Nicolas A, Atkinson J, Capdeville-Atkinson C. Tran NN, et al. Among authors: nicolas a. Cell Calcium. 1995 Nov;18(5):420-8. doi: 10.1016/0143-4160(95)90057-8. Cell Calcium. 1995. PMID: 8581970
A new method for the determination of tissue concentrations of Fura-2 and Fura-2/AM was developed based upon acetonitrile extraction followed by RP-HPLC separation (using tetrahexylammonium as counter-ion), post-column alkaline hydrolysis of Fura-2/AM, and fluorimetric det
A new method for the determination of tissue concentrations of Fura-2 and Fura-2/AM was developed based upon acetonitrile extraction
Determination of cellular thiols and glutathione-related enzyme activities: versatility of high-performance liquid chromatography-spectrofluorimetric detection.
Parmentier C, Leroy P, Wellman M, Nicolas A. Parmentier C, et al. Among authors: nicolas a. J Chromatogr B Biomed Sci Appl. 1998 Nov 20;719(1-2):37-46. doi: 10.1016/s0378-4347(98)00414-9. J Chromatogr B Biomed Sci Appl. 1998. PMID: 9869362
A high-performance liquid chromatography (HPLC) method to determine the most important cellular thiols [reduced glutathione (GSH), cysteine, gamma-glutamylcysteine and cysteinylglycine] is described. ...
A high-performance liquid chromatography (HPLC) method to determine the most important cellular thiols [reduced glutathione (GSH), cy
Hyphenated liquid chromatographic method for the determination of colistin residues in bovine tissues.
Decolin D, Leroy P, Nicolas A, Archimbault P. Decolin D, et al. Among authors: nicolas a. J Chromatogr Sci. 1997 Dec;35(12):557-64. doi: 10.1093/chromsci/35.12.557. J Chromatogr Sci. 1997. PMID: 9397540
This latter step is performed automatically, and the resulting reaction mixture is injected into a switching HPLC system including a precolumn and an analytical column packed with end-capped LiChrospher RP18 (5 microns). ...Relative standard deviation values are les …
This latter step is performed automatically, and the resulting reaction mixture is injected into a switching HPLC system including …
Analytical strategies for the screening of veterinary drugs and their residues in edible products (review), by Aerts et al.: an addendum.
Nicolas A. Nicolas A. J Chromatogr B Biomed Appl. 1996 Apr 26;679(1-2):210-1. doi: 10.1016/0378-4347(95)00579-x. J Chromatogr B Biomed Appl. 1996. PMID: 8998566 No abstract available.
Electrochemical oxidation of CBS-113 A, a new anti-inflammatory drug: applicability to liquid chromatography-electrochemical detection.
Leroy P, Baudrit O, Blanchin MD, Nicolas A, Fabre H. Leroy P, et al. Among authors: nicolas a. J Pharm Biomed Anal. 1995 Aug;13(9):1133-40. doi: 10.1016/0731-7085(95)01532-p. J Pharm Biomed Anal. 1995. PMID: 8573639
The electrochemical properties of a new non-steroidal anti-inflammatory drug (2-hydroxy-4-methylphenyl-2-aminothiazole hydrochloride; CBS-113 A) have been studied using voltammetry in direct current and cyclic modes at glassy carbon disk electrodes. ...An HPLC syste …
The electrochemical properties of a new non-steroidal anti-inflammatory drug (2-hydroxy-4-methylphenyl-2-aminothiazole hydrochloride; …
Rapid liquid chromatographic assay of glutathione in cultured cells.
Leroy P, Nicolas A, Thioudellet C, Oster T, Wellman M, Siest G. Leroy P, et al. Among authors: nicolas a. Biomed Chromatogr. 1993 Mar-Apr;7(2):86-9. doi: 10.1002/bmc.1130070208. Biomed Chromatogr. 1993. PMID: 8485380
The use of a 4 micron particle, 5 cm long column (Superspher 100 RP 18 end-capped) allowed complete analysis of glutathione within 3 min. ...The rapid analysis enabled the processing of a large number of samples in a short time (up to 20 per hour). The method …
The use of a 4 micron particle, 5 cm long column (Superspher 100 RP 18 end-capped) allowed complete analysis of glutathione within 3 …
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