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Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non-Small Cell Lung Cancer.
Sabari JK, Velcheti V, Shimizu K, Strickland MR, Heist RS, Singh M, Nayyar N, Giobbie-Hurder A, Digumarthy SR, Gainor JF, Rajan AP, Nieblas-Bedolla E, Burns AC, Hallin J, Olson P, Christensen JG, Kurz SC, Brastianos PK, Wakimoto H. Sabari JK, et al. Among authors: nieblas bedolla e. Clin Cancer Res. 2022 Aug 2;28(15):3318-3328. doi: 10.1158/1078-0432.CCR-22-0383. Clin Cancer Res. 2022. PMID: 35404402 Free PMC article.
Emerging Immunotherapies in the Treatment of Brain Metastases.
Nieblas-Bedolla E, Nayyar N, Singh M, Sullivan RJ, Brastianos PK. Nieblas-Bedolla E, et al. Oncologist. 2021 Mar;26(3):231-241. doi: 10.1002/onco.13575. Epub 2020 Nov 10. Oncologist. 2021. PMID: 33103803 Free PMC article. Review.
Central Nervous System Metastases.
Nieblas-Bedolla E, Zuccato J, Kluger H, Zadeh G, Brastianos PK. Nieblas-Bedolla E, et al. Hematol Oncol Clin North Am. 2022 Feb;36(1):161-188. doi: 10.1016/j.hoc.2021.08.004. Epub 2021 Oct 25. Hematol Oncol Clin North Am. 2022. PMID: 34711458 Review.
HIF1A signaling selectively supports proliferation of breast cancer in the brain.
Ebright RY, Zachariah MA, Micalizzi DS, Wittner BS, Niederhoffer KL, Nieman LT, Chirn B, Wiley DF, Wesley B, Shaw B, Nieblas-Bedolla E, Atlas L, Szabolcs A, Iafrate AJ, Toner M, Ting DT, Brastianos PK, Haber DA, Maheswaran S. Ebright RY, et al. Nat Commun. 2020 Dec 9;11(1):6311. doi: 10.1038/s41467-020-20144-w. Nat Commun. 2020. PMID: 33298946 Free PMC article.
21 results