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Targeted clearance of p21- but not p16-positive senescent cells prevents radiation-induced osteoporosis and increased marrow adiposity.
Chandra A, Lagnado AB, Farr JN, Doolittle M, Tchkonia T, Kirkland JL, LeBrasseur NK, Robbins PD, Niedernhofer LJ, Ikeno Y, Passos JF, Monroe DG, Pignolo RJ, Khosla S. Chandra A, et al. Among authors: niedernhofer lj. Aging Cell. 2022 May;21(5):e13602. doi: 10.1111/acel.13602. Epub 2022 Apr 1. Aging Cell. 2022. PMID: 35363946 Free PMC article.
NF-κB in Aging and Disease.
Tilstra JS, Clauson CL, Niedernhofer LJ, Robbins PD. Tilstra JS, et al. Among authors: niedernhofer lj. Aging Dis. 2011 Dec;2(6):449-65. Epub 2011 Dec 2. Aging Dis. 2011. PMID: 22396894 Free PMC article.
NF-κB inhibition delays DNA damage-induced senescence and aging in mice.
Tilstra JS, Robinson AR, Wang J, Gregg SQ, Clauson CL, Reay DP, Nasto LA, St Croix CM, Usas A, Vo N, Huard J, Clemens PR, Stolz DB, Guttridge DC, Watkins SC, Garinis GA, Wang Y, Niedernhofer LJ, Robbins PD. Tilstra JS, et al. Among authors: niedernhofer lj. J Clin Invest. 2012 Jul;122(7):2601-12. doi: 10.1172/JCI45785. Epub 2012 Jun 18. J Clin Invest. 2012. PMID: 22706308 Free PMC article.
182 results