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EXD2 promotes homologous recombination by facilitating DNA end resection.
Broderick R, Nieminuszczy J, Baddock HT, Deshpande R, Gileadi O, Paull TT, McHugh PJ, Niedzwiedz W. Broderick R, et al. Among authors: niedzwiedz w. Nat Cell Biol. 2016 Mar;18(3):271-280. doi: 10.1038/ncb3303. Epub 2016 Jan 25. Nat Cell Biol. 2016. PMID: 26807646 Free PMC article.
EXD2 - a new player joins the DSB resection team.
Nieminuszczy J, Broderick R, Niedzwiedz W. Nieminuszczy J, et al. Among authors: niedzwiedz w. Cell Cycle. 2016 Jun 17;15(12):1519-20. doi: 10.1080/15384101.2016.1161997. Epub 2016 May 31. Cell Cycle. 2016. PMID: 27247051 Free PMC article. No abstract available.
Activating ATR, the devil's in the dETAA1l.
Niedzwiedz W. Niedzwiedz W. Nat Cell Biol. 2016 Oct 27;18(11):1120-1122. doi: 10.1038/ncb3431. Nat Cell Biol. 2016. PMID: 27784903 Review.
SAMHD1 acts at stalled replication forks to prevent interferon induction.
Coquel F, Silva MJ, Técher H, Zadorozhny K, Sharma S, Nieminuszczy J, Mettling C, Dardillac E, Barthe A, Schmitz AL, Promonet A, Cribier A, Sarrazin A, Niedzwiedz W, Lopez B, Costanzo V, Krejci L, Chabes A, Benkirane M, Lin YL, Pasero P. Coquel F, et al. Among authors: niedzwiedz w. Nature. 2018 May;557(7703):57-61. doi: 10.1038/s41586-018-0050-1. Epub 2018 Apr 18. Nature. 2018. PMID: 29670289
EXD2 Protects Stressed Replication Forks and Is Required for Cell Viability in the Absence of BRCA1/2.
Nieminuszczy J, Broderick R, Bellani MA, Smethurst E, Schwab RA, Cherdyntseva V, Evmorfopoulou T, Lin YL, Minczuk M, Pasero P, Gagos S, Seidman MM, Niedzwiedz W. Nieminuszczy J, et al. Among authors: niedzwiedz w. Mol Cell. 2019 Aug 8;75(3):605-619.e6. doi: 10.1016/j.molcel.2019.05.026. Epub 2019 Jun 26. Mol Cell. 2019. PMID: 31255466 Free PMC article.
41 results