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DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks.
Mosbech A, Gibbs-Seymour I, Kagias K, Thorslund T, Beli P, Povlsen L, Nielsen SV, Smedegaard S, Sedgwick G, Lukas C, Hartmann-Petersen R, Lukas J, Choudhary C, Pocock R, Bekker-Jensen S, Mailand N. Mosbech A, et al. Among authors: nielsen sv. Nat Struct Mol Biol. 2012 Nov;19(11):1084-92. doi: 10.1038/nsmb.2395. Epub 2012 Oct 7. Nat Struct Mol Biol. 2012. PMID: 23042605
Protein quality control in the nucleus.
Nielsen SV, Poulsen EG, Rebula CA, Hartmann-Petersen R. Nielsen SV, et al. Biomolecules. 2014 Jul 9;4(3):646-61. doi: 10.3390/biom4030646. Biomolecules. 2014. PMID: 25010148 Free PMC article. Review.
Blocking protein quality control to counter hereditary cancers.
Kampmeyer C, Nielsen SV, Clausen L, Stein A, Gerdes AM, Lindorff-Larsen K, Hartmann-Petersen R. Kampmeyer C, et al. Among authors: nielsen sv. Genes Chromosomes Cancer. 2017 Dec;56(12):823-831. doi: 10.1002/gcc.22487. Epub 2017 Sep 6. Genes Chromosomes Cancer. 2017. PMID: 28779490 Review.
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