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Angiogenesis, angiogenic growth factors, and cell adhesion molecules are upregulated in chronic pancreatic diseases: angiogenesis in chronic pancreatitis and in pancreatic cancer.
Kuehn R, Lelkes PI, Bloechle C, Niendorf A, Izbicki JR. Kuehn R, et al. Among authors: niendorf a. Pancreas. 1999 Jan;18(1):96-103. doi: 10.1097/00006676-199901000-00012. Pancreas. 1999. PMID: 9888665
We hypothesized that enhanced angiogenesis might play a pivotal role in the etiology and histopathology of both CP and PCA, and thus form a possible link between precancer and carcinoma. ...Based on this study, we suggest that antiangiogenesis might be a nove …
We hypothesized that enhanced angiogenesis might play a pivotal role in the etiology and histopathology of both CP and PCA, and thus …
A compartment-specific transcriptome analysis reveals survival-relevant marker genes in the stroma fraction of squamous non-small cell lung cancer.
Bendrat K, Stang A, Georgiev G, Geffers R, Haase B, Schütze K, Mogilarov D, Branscheid D, Niendorf A. Bendrat K, et al. Among authors: niendorf a. J Biophotonics. 2012 Apr;5(4):367-77. doi: 10.1002/jbio.201100115. Epub 2012 Jan 26. J Biophotonics. 2012. PMID: 22278766
This study presents a compartment-specific transcriptome analysis of lung squamous cell carcinoma (SCC) samples microdissected into tumor parenchyma and stroma fractions. ...Stromal upregulation of MHC-II genes seems crucial for a clinically relevant antitumor immun …
This study presents a compartment-specific transcriptome analysis of lung squamous cell carcinoma (SCC) samples microdissected into t …
Organ- and tissue-specific expression of the low density lipoprotein receptor. Rapid quantitation by competitive reverse transcriptasepolymerase chain reaction.
Gebhardt A, Niendorf A. Gebhardt A, et al. Among authors: niendorf a. Z Gastroenterol. 1996 Jun;34 Suppl 3:127-8. Z Gastroenterol. 1996. PMID: 8767488
A rapid and sensitive method of quantifying very low-abundant mRNA species by competitive reverse transcriptase-polymerase chain reaction (cRT-PCR) is presented. For each analysis, a defined amount of total cellular RNA is co-reverse transcribed and co-amplified wit
A rapid and sensitive method of quantifying very low-abundant mRNA species by competitive reverse transcriptase-polymerase chain reac
Lipoprotein(a) in the arterial wall.
Beisiegel U, Niendorf A, Wolf K, Reblin T, Rath M. Beisiegel U, et al. Among authors: niendorf a. Eur Heart J. 1990 Aug;11 Suppl E:174-83. doi: 10.1093/eurheartj/11.suppl_e.174. Eur Heart J. 1990. PMID: 2146123
Lp(a) accumulates in the intima, preferentially in plaque areas, dependent on the serum Lp(a) level. Most of the Lp(a) can be located extracellularly, but apo(a) can also be detected in foam cells. A strong co-localization has been observed for …
Lp(a) accumulates in the intima, preferentially in plaque areas, dependent on the serum Lp(a) level. Most of the Lp(a) …
Effects of pravastatin, a hydroxymethylglutaryl-CoA reductase inhibitor, on two human tumour cell lines.
Gebhardt A, Niendorf A. Gebhardt A, et al. Among authors: niendorf a. J Cancer Res Clin Oncol. 1995;121(6):343-9. doi: 10.1007/BF01225686. J Cancer Res Clin Oncol. 1995. PMID: 7797599
Competitive inhibitors of 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase are currently used to treat patients with hypercholesterolaemia. ...Southern blot analysis revealed a 1.5-fold amplification of the HMG-CoA reductase gene in resistant MDA-MB231 cel …
Competitive inhibitors of 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase are currently used to treat patients with hyperc …
Prognostic value of immunohistochemically identifiable tumor cells in lymph nodes of patients with completely resected esophageal cancer.
Izbicki JR, Hosch SB, Pichlmeier U, Rehders A, Busch C, Niendorf A, Passlick B, Broelsch CE, Pantel K. Izbicki JR, et al. Among authors: niendorf a. N Engl J Med. 1997 Oct 23;337(17):1188-94. doi: 10.1056/NEJM199710233371702. N Engl J Med. 1997. PMID: 9337377
A total of 399 lymph nodes obtained from 68 patients were found to be free of tumor by routine histopathological analysis and were studied further for isolated tumor cells by immunohistochemical analysis with the monoclonal anti-epithelial-cell antibody Ber-EP4. ...
A total of 399 lymph nodes obtained from 68 patients were found to be free of tumor by routine histopathological analysis and were st
Expression and prognostic significance of immunoregulatory molecules in esophageal cancer.
Hosch SB, Izbicki JR, Pichlmeier U, Stoecklein N, Niendorf A, Knoefel WT, Broelsch CE, Pantel K. Hosch SB, et al. Among authors: niendorf a. Int J Cancer. 1997 Dec 19;74(6):582-7. doi: 10.1002/(sici)1097-0215(19971219)74:6<582::aid-ijc4>3.0.co;2-q. Int J Cancer. 1997. PMID: 9421352
Kaplan-Meier analyses revealed a significant beneficial influence on relapse-free survival for patients with tumors expressing HLA class I, HLA class II and B7. Cox's regression analyses demonstrated that co-expression of HLA class I and ICAM-1 was a significant and …
Kaplan-Meier analyses revealed a significant beneficial influence on relapse-free survival for patients with tumors expressing HLA cl …
Early lymphatic tumor cell dissemination in pancreatic cancer: frequency and prognostic significance.
Hosch SB, Knoefel WT, Metz S, Stoecklein N, Niendorf A, Broelsch CE, Izbicki JR. Hosch SB, et al. Among authors: niendorf a. Pancreas. 1997 Aug;15(2):154-9. doi: 10.1097/00006676-199708000-00007. Pancreas. 1997. PMID: 9260200
Using multivariate Cox's regression analysis, the presence of Ber-EP4+ cells in "tumor-free" lymph nodes was an independent factor for a significantly reduced relapse-free survival (p = 0.006) and overall survival (p = 0.01). ...Thus patients with a minimal residual …
Using multivariate Cox's regression analysis, the presence of Ber-EP4+ cells in "tumor-free" lymph nodes was an independent factor for a
Increased LDL receptor mRNA expression in colon cancer is correlated with a rise in plasma cholesterol levels after curative surgery.
Niendorf A, Nägele H, Gerding D, Meyer-Pannwitt U, Gebhardt A. Niendorf A, et al. Int J Cancer. 1995 May 16;61(4):461-4. doi: 10.1002/ijc.2910610405. Int J Cancer. 1995. PMID: 7759150
It is currently under debate whether the low serum cholesterol levels that are frequently observed in cancer patients represent a risk factor for/or, rather, are a consequence of the tumour. ...It supports the hypothesis that low cholesterol levels in cancer patient …
It is currently under debate whether the low serum cholesterol levels that are frequently observed in cancer patients represent a ris …
Esophageal cancer: the mode of lymphatic tumor cell spread and its prognostic significance.
Hosch SB, Stoecklein NH, Pichlmeier U, Rehders A, Scheunemann P, Niendorf A, Knoefel WT, Izbicki JR. Hosch SB, et al. Among authors: niendorf a. J Clin Oncol. 2001 Apr 1;19(7):1970-5. doi: 10.1200/JCO.2001.19.7.1970. J Clin Oncol. 2001. PMID: 11283129
PATIENTS AND METHODS: A total of 1,584 resected lymph nodes were obtained from 86 patients with resected esophageal carcinoma and evaluated by routine histopathology. ...CONCLUSION: Histopathologically and immunohistochemically detectable skip metastases are a frequ …
PATIENTS AND METHODS: A total of 1,584 resected lymph nodes were obtained from 86 patients with resected esophageal carcinoma and eva …
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