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Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance.
König J, Nies AT, Cui Y, Leier I, Keppler D. König J, et al. Among authors: nies at. Biochim Biophys Acta. 1999 Dec 6;1461(2):377-94. doi: 10.1016/s0005-2736(99)00169-8. Biochim Biophys Acta. 1999. PMID: 10581368 Review.
Expression of the apical conjugate export pump, Mrp2, in the polarized hepatoma cell line, WIF-B.
Nies AT, Cantz T, Brom M, Leier I, Keppler D. Nies AT, et al. Hepatology. 1998 Nov;28(5):1332-40. doi: 10.1002/hep.510280523. Hepatology. 1998. PMID: 9794919
Export pumps for anionic conjugates encoded by MRP genes.
Keppler D, Cui Y, König J, Leier I, Nies A. Keppler D, et al. Adv Enzyme Regul. 1999;39:237-46. doi: 10.1016/s0065-2571(98)00015-6. Adv Enzyme Regul. 1999. PMID: 10470375
Purification of the human apical conjugate export pump MRP2 reconstitution and functional characterization as substrate-stimulated ATPase.
Hagmann W, Nies AT, König J, Frey M, Zentgraf H, Keppler D. Hagmann W, et al. Among authors: nies at. Eur J Biochem. 1999 Oct 1;265(1):281-9. doi: 10.1046/j.1432-1327.1999.00735.x. Eur J Biochem. 1999. PMID: 10491184
A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane.
König J, Cui Y, Nies AT, Keppler D. König J, et al. Among authors: nies at. Am J Physiol Gastrointest Liver Physiol. 2000 Jan;278(1):G156-64. doi: 10.1152/ajpgi.2000.278.1.G156. Am J Physiol Gastrointest Liver Physiol. 2000. PMID: 10644574
Characterization of the 5'-flanking region of the human multidrug resistance protein 2 (MRP2) gene and its regulation in comparison withthe multidrug resistance protein 3 (MRP3) gene.
Stöckel B, König J, Nies AT, Cui Y, Brom M, Keppler D. Stöckel B, et al. Among authors: nies at. Eur J Biochem. 2000 Mar;267(5):1347-58. doi: 10.1046/j.1432-1327.2000.01106.x. Eur J Biochem. 2000. PMID: 10691972
MRP2, a human conjugate export pump, is present and transports fluo 3 into apical vacuoles of Hep G2 cells.
Cantz T, Nies AT, Brom M, Hofmann AF, Keppler D. Cantz T, et al. Among authors: nies at. Am J Physiol Gastrointest Liver Physiol. 2000 Apr;278(4):G522-31. doi: 10.1152/ajpgi.2000.278.4.G522. Am J Physiol Gastrointest Liver Physiol. 2000. PMID: 10762605
Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide.
König J, Cui Y, Nies AT, Keppler D. König J, et al. Among authors: nies at. J Biol Chem. 2000 Jul 28;275(30):23161-8. doi: 10.1074/jbc.M001448200. J Biol Chem. 2000. PMID: 10779507
Localization, substrate specificity, and drug resistance conferred by conjugate export pumps of the MRP family.
Keppler D, Kamisako T, Leier I, Cui Y, Nies AT, Tsujii H, König J. Keppler D, et al. Among authors: nies at. Adv Enzyme Regul. 2000;40:339-49. doi: 10.1016/s0065-2571(99)00022-9. Adv Enzyme Regul. 2000. PMID: 10828358 No abstract available.
Impaired protein maturation of the conjugate export pump multidrug resistance protein 2 as a consequence of a deletion mutation in Dubin-Johnson syndrome.
Keitel V, Kartenbeck J, Nies AT, Spring H, Brom M, Keppler D. Keitel V, et al. Among authors: nies at. Hepatology. 2000 Dec;32(6):1317-28. doi: 10.1053/jhep.2000.19791. Hepatology. 2000. PMID: 11093739
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