Nies AT - Search Results

1

Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy.

Nies AT, Koepsell H, Damme K, Schwab M. Nies AT, et al. Handb Exp Pharmacol. 2011;(201):105-67. doi: 10.1007/978-3-642-14541-4_3. Handb Exp Pharmacol. 2011. PMID: 21103969 Review.

2

The apical conjugate efflux pump ABCC2 (MRP2).

Nies AT, Keppler D. Nies AT, et al. Pflugers Arch. 2007 Feb;453(5):643-59. doi: 10.1007/s00424-006-0109-y. Epub 2006 Jul 18. Pflugers Arch. 2007. PMID: 16847695 Review.

3

The role of membrane transporters in drug delivery to brain tumors.

Nies AT. Nies AT. Cancer Lett. 2007 Aug 28;254(1):11-29. doi: 10.1016/j.canlet.2006.12.023. Epub 2007 Jan 31. Cancer Lett. 2007. PMID: 17275180 Review.

4

Vectorial transport of the plant alkaloid berberine by double-transfected cells expressing the human organic cation transporter 1 (OCT1, SLC22A1) and the efflux pump MDR1 P-glycoprotein (ABCB1).

Nies AT, Herrmann E, Brom M, Keppler D. Nies AT, et al. Naunyn Schmiedebergs Arch Pharmacol. 2008 Feb;376(6):449-61. doi: 10.1007/s00210-007-0219-x. Epub 2007 Dec 19. Naunyn Schmiedebergs Arch Pharmacol. 2008. PMID: 18157518

5

Interplay of conjugating enzymes with OATP uptake transporters and ABCC/MRP efflux pumps in the elimination of drugs.

Nies AT, Schwab M, Keppler D. Nies AT, et al. Expert Opin Drug Metab Toxicol. 2008 May;4(5):545-68. doi: 10.1517/17425255.4.5.545. Expert Opin Drug Metab Toxicol. 2008. PMID: 18484914 Review.

6

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver.

Nies AT, Koepsell H, Winter S, Burk O, Klein K, Kerb R, Zanger UM, Keppler D, Schwab M, Schaeffeler E. Nies AT, et al. Hepatology. 2009 Oct;50(4):1227-40. doi: 10.1002/hep.23103. Hepatology. 2009. PMID: 19591196

7

Proton pump inhibitors inhibit metformin uptake by organic cation transporters (OCTs).

Nies AT, Hofmann U, Resch C, Schaeffeler E, Rius M, Schwab M. Nies AT, et al. PLoS One. 2011;6(7):e22163. doi: 10.1371/journal.pone.0022163. Epub 2011 Jul 14. PLoS One. 2011. PMID: 21779389 Free PMC article.

8

Mammalian MATE (SLC47A) transport proteins: impact on efflux of endogenous substrates and xenobiotics.

Damme K, Nies AT, Schaeffeler E, Schwab M. Damme K, et al. Among authors: nies at. Drug Metab Rev. 2011 Nov;43(4):499-523. doi: 10.3109/03602532.2011.602687. Epub 2011 Sep 17. Drug Metab Rev. 2011. PMID: 21923552 Review.

9

Organic cation transporter pharmacogenomics and drug-drug interaction.

Nies AT, Schwab M. Nies AT, et al. Expert Rev Clin Pharmacol. 2010 Nov;3(6):707-11. doi: 10.1586/ecp.10.60. Expert Rev Clin Pharmacol. 2010. PMID: 22111772 No abstract available.

10

DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma.

Schaeffeler E, Hellerbrand C, Nies AT, Winter S, Kruck S, Hofmann U, van der Kuip H, Zanger UM, Koepsell H, Schwab M. Schaeffeler E, et al. Among authors: nies at. Genome Med. 2011 Dec 23;3(12):82. doi: 10.1186/gm298. Genome Med. 2011. PMID: 22196450 Free PMC article.

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