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Population-based study of lymphoma in Germany: rationale, study design and first results.
Becker N, Deeg E, Nieters A. Becker N, et al. Leuk Res. 2004 Jul;28(7):713-24. doi: 10.1016/j.leukres.2003.11.010. Leuk Res. 2004. PMID: 15158093 Clinical Trial.
A multi-centre, population-based case-control study of lymphoma among adults was conducted in Germany from 1999-2003. The study comprised 700 incident cases (Hodgkin lymphomas and non Hodgkin's lymphoma, NHL) in the age range 18-80 years and 700 age-, sex- and area-matched
A multi-centre, population-based case-control study of lymphoma among adults was conducted in Germany from 1999-2003. The study compr
Cross-sectional study on cytokine polymorphisms, cytokine production after T-cell stimulation and clinical parameters in a random sample of a German population.
Nieters A, Brems S, Becker N. Nieters A, et al. Hum Genet. 2001 Mar;108(3):241-8. doi: 10.1007/s004390100464. Hum Genet. 2001. PMID: 11354638
We investigated, in a random sample of a German population, the association of polymorphisms in the genes encoding the cytokines interleukin 2 (IL-2), interleukin 4 receptor (IL-4R), interleukin 6 (IL-6), interleukin 10, interferon gamma (IFNG), tumor necrosis facto …
We investigated, in a random sample of a German population, the association of polymorphisms in the genes encoding the cytokin …
Low-to-moderate alcohol consumption and breast cancer risk by age 50 years among women in Germany.
Kropp S, Becher H, Nieters A, Chang-Claude J. Kropp S, et al. Am J Epidemiol. 2001 Oct 1;154(7):624-34. doi: 10.1093/aje/154.7.624. Am J Epidemiol. 2001. PMID: 11581096
Studies of the association between alcohol drinking and breast cancer show a tendency towards an increase in risk for high consumption levels but yield less consistent results for low-to-moderate levels, particularly among premenopausal women. In a population-based …
Studies of the association between alcohol drinking and breast cancer show a tendency towards an increase in risk for high consumptio …
Single nucleotide polymorphism--disease relationships: statistical issues for the performance of association studies.
Becker N, Nieters A, Rittgen W. Becker N, et al. Mutat Res. 2003 Apr 9;525(1-2):11-8. doi: 10.1016/s0027-5107(02)00283-x. Mutat Res. 2003. PMID: 12650901 Review.
We propose a two-step sequential approach in order to (a) allow a study--internal control of reproducibility and (b) stop a study or lab analysis prematurely to save valuable specimen, time and costs. ...
We propose a two-step sequential approach in order to (a) allow a study--internal control of reproducibility and (b) st …
Association of polymorphisms in Th1, Th2 cytokine genes with hayfever and atopy in a subsample of EPIC-Heidelberg.
Nieters A, Linseisen J, Becker N. Nieters A, et al. Clin Exp Allergy. 2004 Mar;34(3):346-53. doi: 10.1111/j.1365-2222.2004.01889.x. Clin Exp Allergy. 2004. PMID: 15005726
METHODS: From a subsample of the European Prospective Investigation into Cancer and Nutrition-Heidelberg, 322 subjects with hayfever and 322 age- and sex-matched non-allergic controls were selected and genotypes determined for 15 polymorphisms in 13 genes. ...CONCLUSION: O …
METHODS: From a subsample of the European Prospective Investigation into Cancer and Nutrition-Heidelberg, 322 subjects with hayfever …
Medical history and risk for lymphoma: results of a population-based case-control study in Germany.
Becker N, Deeg E, Rüdiger T, Nieters A. Becker N, et al. Eur J Cancer. 2005 Jan;41(1):133-42. doi: 10.1016/j.ejca.2004.08.028. Eur J Cancer. 2005. PMID: 15617998
Overall, we found decreased risks for a history of repeated diarrhoea, warts, arthrosis, allergies, and appendectomy (at a younger age). Elevated risks for lymphoma correlated with tonsillectomy (at a younger age), whereas null results were found for selected …
Overall, we found decreased risks for a history of repeated diarrhoea, warts, arthrosis, allergies, and appendectomy (at a you …
Effect of cytokine genotypes on the hepatitis B virus-hepatocellular carcinoma association.
Nieters A, Yuan JM, Sun CL, Zhang ZQ, Stoehlmacher J, Govindarajan S, Yu MC. Nieters A, et al. Cancer. 2005 Feb 15;103(4):740-8. doi: 10.1002/cncr.20842. Cancer. 2005. PMID: 15643599
METHODS: The authors examined the correlation between polymorphisms in T-helper 1 (Th1) and Th2 cytokine genes among a group of 250 patients with incident hepatocellular carcinoma (cases) and a group of 250 hospital controls who were matched individually to the inde …
METHODS: The authors examined the correlation between polymorphisms in T-helper 1 (Th1) and Th2 cytokine genes among a group of 250 p …
Tobacco and alcohol consumption and risk of lymphoma: results of a population-based case-control study in Germany.
Nieters A, Deeg E, Becker N. Nieters A, et al. Int J Cancer. 2006 Jan 15;118(2):422-30. doi: 10.1002/ijc.21306. Int J Cancer. 2006. PMID: 16080191
Although biologic rationale for a protective effect of alcohol consumption may be given, a more in-depth analysis involving genetic markers is indicated to clarify if ethanol, other components in alcoholic beverages, or factors associated with moderate drinking redu …
Although biologic rationale for a protective effect of alcohol consumption may be given, a more in-depth analysis involving ge …
Occupation and malignant lymphoma: a population based case control study in Germany.
Mester B, Nieters A, Deeg E, Elsner G, Becker N, Seidler A. Mester B, et al. Occup Environ Med. 2006 Jan;63(1):17-26. doi: 10.1136/oem.2005.020453. Occup Environ Med. 2006. PMID: 16361401 Free PMC article. Clinical Trial.
AIMS: To identify occupations suspected to be associated with malignant lymphoma and to generate new hypotheses about occupational risks in a multicentre, population based case control study. ...For each newly recruited lymphoma case, a sex, region, and age matched …
AIMS: To identify occupations suspected to be associated with malignant lymphoma and to generate new hypotheses about occupational risks in …
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