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Combining genomewide association study and lung eQTL analysis provides evidence for novel genes associated with asthma.
Nieuwenhuis MA, Siedlinski M, van den Berge M, Granell R, Li X, Niens M, van der Vlies P, Altmüller J, Nürnberg P, Kerkhof M, van Schayck OC, Riemersma RA, van der Molen T, de Monchy JG, Bossé Y, Sandford A, Bruijnzeel-Koomen CA, Gerth van Wijk R, Ten Hacken NH, Timens W, Boezen HM, Henderson J, Kabesch M, Vonk JM, Postma DS, Koppelman GH. Nieuwenhuis MA, et al. Allergy. 2016 Dec;71(12):1712-1720. doi: 10.1111/all.12990. Epub 2016 Aug 22. Allergy. 2016. PMID: 27439200 Free PMC article.
Novel genes and insights in complete asthma remission: A genome-wide association study on clinical and complete asthma remission.
Vonk JM, Nieuwenhuis MAE, Dijk FN, Boudier A, Siroux V, Bouzigon E, Probst-Hensch N, Imboden M, Keidel D, Sin D, Bossé Y, Hao K, van den Berge M, Faiz A, Koppelman GH, Postma DS. Vonk JM, et al. Among authors: nieuwenhuis mae. Clin Exp Allergy. 2018 Oct;48(10):1286-1296. doi: 10.1111/cea.13181. Epub 2018 Jun 19. Clin Exp Allergy. 2018. PMID: 29786918
Genetic variants of inducible costimulator are associated with allergic asthma susceptibility.
Andiappan AK, Narayanan S, Myers RA, Lee B, Nieuwenhuis MA, Nardin A, Park CS, Shin HD, Kim JH, Westra HJ, Franke L, Esko T, Metspalu A, Teo YY, Saw SM, Khor CC, Liu J, Koppelman GH, Postma DS, Poidinger M, Connolly JE, Wang de Y, Rotzschke O, Curotto de Lafaille MA, Chew FT. Andiappan AK, et al. Among authors: nieuwenhuis ma. J Allergy Clin Immunol. 2015 Feb;135(2):556-8. doi: 10.1016/j.jaci.2014.06.028. Epub 2014 Aug 7. J Allergy Clin Immunol. 2015. PMID: 25109803 No abstract available.
Latrophilin receptors: novel bronchodilator targets in asthma.
Faiz A, Donovan C, Nieuwenhuis MA, van den Berge M, Postma DS, Yao S, Park CY, Hirsch R, Fredberg JJ, Tjin G, Halayko AJ, Rempel KL, Ward JP, Lee T, Bossé Y, Nickle DC, Obeidat M, Vonk JM, Black JL, Oliver BG, Krishnan R, McParland B, Bourke JE, Burgess JK. Faiz A, et al. Among authors: nieuwenhuis ma. Thorax. 2017 Jan;72(1):74-82. doi: 10.1136/thoraxjnl-2015-207236. Epub 2016 Jun 20. Thorax. 2017. PMID: 27325752 Free PMC article.
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
Demenais F, Margaritte-Jeannin P, Barnes KC, Cookson WOC, Altmüller J, Ang W, Barr RG, Beaty TH, Becker AB, Beilby J, Bisgaard H, Bjornsdottir US, Bleecker E, Bønnelykke K, Boomsma DI, Bouzigon E, Brightling CE, Brossard M, Brusselle GG, Burchard E, Burkart KM, Bush A, Chan-Yeung M, Chung KF, Couto Alves A, Curtin JA, Custovic A, Daley D, de Jongste JC, Del-Rio-Navarro BE, Donohue KM, Duijts L, Eng C, Eriksson JG, Farrall M, Fedorova Y, Feenstra B, Ferreira MA; Australian Asthma Genetics Consortium (AAGC) collaborators; Freidin MB, Gajdos Z, Gauderman J, Gehring U, Geller F, Genuneit J, Gharib SA, Gilliland F, Granell R, Graves PE, Gudbjartsson DF, Haahtela T, Heckbert SR, Heederik D, Heinrich J, Heliövaara M, Henderson J, Himes BE, Hirose H, Hirschhorn JN, Hofman A, Holt P, Hottenga J, Hudson TJ, Hui J, Imboden M, Ivanov V, Jaddoe VWV, James A, Janson C, Jarvelin MR, Jarvis D, Jones G, Jonsdottir I, Jousilahti P, Kabesch M, Kähönen M, Kantor DB, Karunas AS, Khusnutdinova E, Koppelman GH, Kozyrskyj AL, Kreiner E, Kubo M, Kumar R, Kumar A, Kuokkanen M, Lahousse L, Laitinen T, Laprise C, Lathrop M, Lau S, Lee YA, Lehtimäki T, Letort S, Levin AM, Li G, Liang L, Loehr LR, London SJ, L… See abstract for full author list ➔ Demenais F, et al. Among authors: nieuwenhuis mae. Nat Genet. 2018 Jan;50(1):42-53. doi: 10.1038/s41588-017-0014-7. Epub 2017 Dec 22. Nat Genet. 2018. PMID: 29273806 Free PMC article.
Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels.
Portelli MA, Siedlinski M, Stewart CE, Postma DS, Nieuwenhuis MA, Vonk JM, Nurnberg P, Altmuller J, Moffatt MF, Wardlaw AJ, Parker SG, Connolly MJ, Koppelman GH, Sayers I. Portelli MA, et al. Among authors: nieuwenhuis ma. FASEB J. 2014 Feb;28(2):923-34. doi: 10.1096/fj.13-240879. Epub 2013 Nov 18. FASEB J. 2014. PMID: 24249636 Free PMC article.
15 results