Nigam SK - Search Results

1

Organic anion and cation SLC22 "drug" transporter (Oat1, Oat3, and Oct1) regulation during development and maturation of the kidney proximal tubule.

Gallegos TF, Martovetsky G, Kouznetsova V, Bush KT, Nigam SK. Gallegos TF, et al. Among authors: nigam sk. PLoS One. 2012;7(7):e40796. doi: 10.1371/journal.pone.0040796. Epub 2012 Jul 13. PLoS One. 2012. PMID: 22808265 Free PMC article.

2

Drug and toxicant handling by the OAT organic anion transporters in the kidney and other tissues.

Nigam SK, Bush KT, Bhatnagar V. Nigam SK, et al. Nat Clin Pract Nephrol. 2007 Aug;3(8):443-8. doi: 10.1038/ncpneph0558. Nat Clin Pract Nephrol. 2007. PMID: 17653123 Review.

3

Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter-Organic anion transporter1 (Oat1).

Kouznetsova VL, Tsigelny IF, Nagle MA, Nigam SK. Kouznetsova VL, et al. Among authors: nigam sk. Bioorg Med Chem. 2011 Jun 1;19(11):3320-40. doi: 10.1016/j.bmc.2011.04.045. Epub 2011 Apr 28. Bioorg Med Chem. 2011. PMID: 21571536 Free PMC article.

4

A protein kinase A and Wnt-dependent network regulating an intermediate stage in epithelial tubulogenesis during kidney development.

Gallegos TF, Kouznetsova V, Kudlicka K, Sweeney DE, Bush KT, Willert K, Farquhar MG, Nigam SK. Gallegos TF, et al. Among authors: nigam sk. Dev Biol. 2012 Apr 1;364(1):11-21. doi: 10.1016/j.ydbio.2012.01.014. Epub 2012 Jan 24. Dev Biol. 2012. PMID: 22290330 Free PMC article.

5

Multispecific drug transporter Slc22a8 (Oat3) regulates multiple metabolic and signaling pathways.

Wu W, Jamshidi N, Eraly SA, Liu HC, Bush KT, Palsson BO, Nigam SK. Wu W, et al. Among authors: nigam sk. Drug Metab Dispos. 2013 Oct;41(10):1825-34. doi: 10.1124/dmd.113.052647. Epub 2013 Aug 6. Drug Metab Dispos. 2013. PMID: 23920220 Free PMC article.

6

Hepatocyte nuclear factors 4α and 1α regulate kidney developmental expression of drug-metabolizing enzymes and drug transporters.

Martovetsky G, Tee JB, Nigam SK. Martovetsky G, et al. Among authors: nigam sk. Mol Pharmacol. 2013 Dec;84(6):808-23. doi: 10.1124/mol.113.088229. Epub 2013 Sep 13. Mol Pharmacol. 2013. PMID: 24038112 Free PMC article.

7

The organic anion transporter (OAT) family: a systems biology perspective.

Nigam SK, Bush KT, Martovetsky G, Ahn SY, Liu HC, Richard E, Bhatnagar V, Wu W. Nigam SK, et al. Physiol Rev. 2015 Jan;95(1):83-123. doi: 10.1152/physrev.00025.2013. Physiol Rev. 2015. PMID: 25540139 Free PMC article. Review.

8

Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters.

Nigam SK, Wu W, Bush KT, Hoenig MP, Blantz RC, Bhatnagar V. Nigam SK, et al. Clin J Am Soc Nephrol. 2015 Nov 6;10(11):2039-49. doi: 10.2215/CJN.02440314. Epub 2015 Oct 21. Clin J Am Soc Nephrol. 2015. PMID: 26490509 Free PMC article.

9

Kidney versus Liver Specification of SLC and ABC Drug Transporters, Tight Junction Molecules, and Biomarkers.

Martovetsky G, Bush KT, Nigam SK. Martovetsky G, et al. Among authors: nigam sk. Drug Metab Dispos. 2016 Jul;44(7):1050-60. doi: 10.1124/dmd.115.068254. Epub 2016 Apr 4. Drug Metab Dispos. 2016. PMID: 27044799 Free PMC article.

10

An Organic Anion Transporter 1 (OAT1)-centered Metabolic Network.

Liu HC, Jamshidi N, Chen Y, Eraly SA, Cho SY, Bhatnagar V, Wu W, Bush KT, Abagyan R, Palsson BO, Nigam SK. Liu HC, et al. Among authors: nigam sk. J Biol Chem. 2016 Sep 9;291(37):19474-86. doi: 10.1074/jbc.M116.745216. Epub 2016 Jul 20. J Biol Chem. 2016. PMID: 27440044 Free PMC article.

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