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MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling.
Huang S, Hölzel M, Knijnenburg T, Schlicker A, Roepman P, McDermott U, Garnett M, Grernrum W, Sun C, Prahallad A, Groenendijk FH, Mittempergher L, Nijkamp W, Neefjes J, Salazar R, Ten Dijke P, Uramoto H, Tanaka F, Beijersbergen RL, Wessels LF, Bernards R. Huang S, et al. Among authors: nijkamp w. Cell. 2012 Nov 21;151(5):937-50. doi: 10.1016/j.cell.2012.10.035. Cell. 2012. PMID: 23178117 Free PMC article.
A large-scale RNAi screen in human cells identifies new components of the p53 pathway.
Berns K, Hijmans EM, Mullenders J, Brummelkamp TR, Velds A, Heimerikx M, Kerkhoven RM, Madiredjo M, Nijkamp W, Weigelt B, Agami R, Ge W, Cavet G, Linsley PS, Beijersbergen RL, Bernards R. Berns K, et al. Among authors: nijkamp w. Nature. 2004 Mar 25;428(6981):431-7. doi: 10.1038/nature02371. Nature. 2004. PMID: 15042092
Loss of ARID1A Activates ANXA1, which Serves as a Predictive Biomarker for Trastuzumab Resistance.
Berns K, Sonnenblick A, Gennissen A, Brohée S, Hijmans EM, Evers B, Fumagalli D, Desmedt C, Loibl S, Denkert C, Neven P, Guo W, Zhang F, Knijnenburg TA, Bosse T, van der Heijden MS, Hindriksen S, Nijkamp W, Wessels LF, Joensuu H, Mills GB, Beijersbergen RL, Sotiriou C, Bernards R. Berns K, et al. Among authors: nijkamp w. Clin Cancer Res. 2016 Nov 1;22(21):5238-5248. doi: 10.1158/1078-0432.CCR-15-2996. Epub 2016 May 12. Clin Cancer Res. 2016. PMID: 27172896
A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation.
Westerman BA, Braat AK, Taub N, Potman M, Vissers JH, Blom M, Verhoeven E, Stoop H, Gillis A, Velds A, Nijkamp W, Beijersbergen R, Huber LA, Looijenga LH, van Lohuizen M. Westerman BA, et al. Among authors: nijkamp w. J Exp Med. 2011 Dec 19;208(13):2675-89. doi: 10.1084/jem.20102037. Epub 2011 Dec 5. J Exp Med. 2011. PMID: 22143885 Free PMC article.
Telomerase-independent regulation of ATR by human telomerase RNA.
Kedde M, le Sage C, Duursma A, Zlotorynski E, van Leeuwen B, Nijkamp W, Beijersbergen R, Agami R. Kedde M, et al. Among authors: nijkamp w. J Biol Chem. 2006 Dec 29;281(52):40503-14. doi: 10.1074/jbc.M607676200. Epub 2006 Nov 10. J Biol Chem. 2006. PMID: 17098743 Free article.
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