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AcrAB and related multidrug efflux pumps of Escherichia coli.
Nikaido H, Zgurskaya HI. Nikaido H, et al. J Mol Microbiol Biotechnol. 2001 Apr;3(2):215-8. J Mol Microbiol Biotechnol. 2001. PMID: 11321576 Review.
Physical interaction between the phage lambda receptor protein and the carrier-immobilized maltose-binding protein of Escherichia coli.
Bavoil P, Nikaido H. Bavoil P, et al. Among authors: nikaido h. J Biol Chem. 1981 Nov 25;256(22):11385-8. J Biol Chem. 1981. PMID: 6457826
Maltose transport system of Escherichia coli: an ABC-type transporter.
Nikaido H. Nikaido H. FEBS Lett. 1994 Jun 6;346(1):55-8. doi: 10.1016/0014-5793(94)00315-7. FEBS Lett. 1994. PMID: 8206159 Review.
Interaction between maltose-binding protein and the membrane-associated maltose transporter complex in Escherichia coli.
Dean DA, Hor LI, Shuman HA, Nikaido H. Dean DA, et al. Among authors: nikaido h. Mol Microbiol. 1992 Aug;6(15):2033-40. doi: 10.1111/j.1365-2958.1992.tb01376.x. Mol Microbiol. 1992. PMID: 1406246
Multidrug efflux pump AcrAB of Salmonella typhimurium excretes only those beta-lactam antibiotics containing lipophilic side chains.
Nikaido H, Basina M, Nguyen V, Rosenberg EY. Nikaido H, et al. J Bacteriol. 1998 Sep;180(17):4686-92. doi: 10.1128/JB.180.17.4686-4692.1998. J Bacteriol. 1998. PMID: 9721312 Free PMC article.
We found that the previously reported SS-B drug-supersusceptible mutant of Salmonella typhimurium (S. Sukupolvi, M. Vaara, I. M. Helander, P. Viljanen, and P. H. Makela, J. Bacteriol. 159:704-712, 1984) had a mutation in the acrAB operon. ...The exclusion of such compounds …
We found that the previously reported SS-B drug-supersusceptible mutant of Salmonella typhimurium (S. Sukupolvi, M. Vaara, I. M. Helander, P …
It takes three to tango.
Lomovskaya O, Zgurskaya HI, Nikaido H. Lomovskaya O, et al. Among authors: nikaido h. Nat Biotechnol. 2002 Dec;20(12):1210-2. doi: 10.1038/nbt1202-1210. Nat Biotechnol. 2002. PMID: 12454673 No abstract available.
Effect of site-directed mutations in multidrug efflux pump AcrB examined by quantitative efflux assays.
Kinana AD, Vargiu AV, Nikaido H. Kinana AD, et al. Among authors: nikaido h. Biochem Biophys Res Commun. 2016 Nov 25;480(4):552-557. doi: 10.1016/j.bbrc.2016.10.083. Epub 2016 Oct 24. Biochem Biophys Res Commun. 2016. PMID: 27789287 Free PMC article.
Aminoacyl β-naphthylamides as substrates and modulators of AcrB multidrug efflux pump.
Kinana AD, Vargiu AV, May T, Nikaido H. Kinana AD, et al. Among authors: nikaido h. Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1405-10. doi: 10.1073/pnas.1525143113. Epub 2016 Jan 19. Proc Natl Acad Sci U S A. 2016. PMID: 26787896 Free PMC article.
Reversal of the Drug Binding Pocket Defects of the AcrB Multidrug Efflux Pump Protein of Escherichia coli.
Soparkar K, Kinana AD, Weeks JW, Morrison KD, Nikaido H, Misra R. Soparkar K, et al. Among authors: nikaido h. J Bacteriol. 2015 Oct;197(20):3255-64. doi: 10.1128/JB.00547-15. Epub 2015 Aug 3. J Bacteriol. 2015. PMID: 26240069 Free PMC article.
The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria.
Li XZ, Plésiat P, Nikaido H. Li XZ, et al. Among authors: nikaido h. Clin Microbiol Rev. 2015 Apr;28(2):337-418. doi: 10.1128/CMR.00117-14. Clin Microbiol Rev. 2015. PMID: 25788514 Free PMC article. Review.
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