Nilsen J - Search Results

1

Unraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based Therapeutics.

Sand KM, Bern M, Nilsen J, Noordzij HT, Sandlie I, Andersen JT. Sand KM, et al. Among authors: nilsen j. Front Immunol. 2015 Jan 26;5:682. doi: 10.3389/fimmu.2014.00682. eCollection 2014. Front Immunol. 2015. PMID: 25674083 Free PMC article. Review.

2

Interaction with both domain I and III of albumin is required for optimal pH-dependent binding to the neonatal Fc receptor (FcRn).

Sand KM, Bern M, Nilsen J, Dalhus B, Gunnarsen KS, Cameron J, Grevys A, Bunting K, Sandlie I, Andersen JT. Sand KM, et al. Among authors: nilsen j. J Biol Chem. 2014 Dec 12;289(50):34583-94. doi: 10.1074/jbc.M114.587675. Epub 2014 Oct 24. J Biol Chem. 2014. PMID: 25344603 Free PMC article.

3

The role of albumin receptors in regulation of albumin homeostasis: Implications for drug delivery.

Bern M, Sand KM, Nilsen J, Sandlie I, Andersen JT. Bern M, et al. Among authors: nilsen j. J Control Release. 2015 Aug 10;211:144-62. doi: 10.1016/j.jconrel.2015.06.006. Epub 2015 Jun 6. J Control Release. 2015. PMID: 26055641 Review.

4

A human endothelial cell-based recycling assay for screening of FcRn targeted molecules.

Grevys A, Nilsen J, Sand KMK, Daba MB, Øynebråten I, Bern M, McAdam MB, Foss S, Schlothauer T, Michaelsen TE, Christianson GJ, Roopenian DC, Blumberg RS, Sandlie I, Andersen JT. Grevys A, et al. Among authors: nilsen j. Nat Commun. 2018 Feb 12;9(1):621. doi: 10.1038/s41467-018-03061-x. Nat Commun. 2018. PMID: 29434196 Free PMC article.

5

Human and mouse albumin bind their respective neonatal Fc receptors differently.

Nilsen J, Bern M, Sand KMK, Grevys A, Dalhus B, Sandlie I, Andersen JT. Nilsen J, et al. Sci Rep. 2018 Oct 2;8(1):14648. doi: 10.1038/s41598-018-32817-0. Sci Rep. 2018. PMID: 30279529 Free PMC article.

6

An intact C-terminal end of albumin is required for its long half-life in humans.

Nilsen J, Trabjerg E, Grevys A, Azevedo C, Brennan SO, Stensland M, Wilson J, Sand KMK, Bern M, Dalhus B, Roopenian DC, Sandlie I, Rand KD, Andersen JT. Nilsen J, et al. Commun Biol. 2020 Apr 20;3(1):181. doi: 10.1038/s42003-020-0903-7. Commun Biol. 2020. PMID: 32313072 Free PMC article.

7

Engineered albumin-functionalized nanoparticles for improved FcRn binding enhance oral delivery of insulin.

Azevedo C, Nilsen J, Grevys A, Nunes R, Andersen JT, Sarmento B. Azevedo C, et al. Among authors: nilsen j. J Control Release. 2020 Nov 10;327:161-173. doi: 10.1016/j.jconrel.2020.08.005. Epub 2020 Aug 7. J Control Release. 2020. PMID: 32771477

8

An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics.

Bern M, Nilsen J, Ferrarese M, Sand KMK, Gjølberg TT, Lode HE, Davidson RJ, Camire RM, Bækkevold ES, Foss S, Grevys A, Dalhus B, Wilson J, Høydahl LS, Christianson GJ, Roopenian DC, Schlothauer T, Michaelsen TE, Moe MC, Lombardi S, Pinotti M, Sandlie I, Branchini A, Andersen JT. Bern M, et al. Among authors: nilsen j. Sci Transl Med. 2020 Oct 14;12(565):eabb0580. doi: 10.1126/scitranslmed.abb0580. Sci Transl Med. 2020. PMID: 33055243

9

The neonatal Fc receptor in mucosal immune regulation.

Aaen KH, Anthi AK, Sandlie I, Nilsen J, Mester S, Andersen JT. Aaen KH, et al. Among authors: nilsen j. Scand J Immunol. 2021 Feb;93(2):e13017. doi: 10.1111/sji.13017. Epub 2021 Jan 17. Scand J Immunol. 2021. PMID: 33351196 Free article. Review.

10

Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo.

Mester S, Evers M, Meyer S, Nilsen J, Greiff V, Sandlie I, Leusen J, Andersen JT. Mester S, et al. Among authors: nilsen j. MAbs. 2021 Jan-Dec;13(1):1893888. doi: 10.1080/19420862.2021.1893888. MAbs. 2021. PMID: 33691596 Free PMC article.

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