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Re-assembled botulinum neurotoxin inhibits CNS functions without systemic toxicity.
Ferrari E, Maywood ES, Restani L, Caleo M, Pirazzini M, Rossetto O, Hastings MH, Niranjan D, Schiavo G, Davletov B. Ferrari E, et al. Among authors: niranjan d. Toxins (Basel). 2011 Apr;3(4):345-55. doi: 10.3390/toxins3040345. Epub 2011 Mar 24. Toxins (Basel). 2011. PMID: 22069712 Free PMC article.
Synthetic self-assembling clostridial chimera for modulation of sensory functions.
Ferrari E, Gu C, Niranjan D, Restani L, Rasetti-Escargueil C, Obara I, Geranton SM, Arsenault J, Goetze TA, Harper CB, Nguyen TH, Maywood E, O'Brien J, Schiavo G, Wheeler DW, Meunier FA, Hastings M, Edwardson JM, Sesardic D, Caleo M, Hunt SP, Davletov B. Ferrari E, et al. Among authors: niranjan d. Bioconjug Chem. 2013 Oct 16;24(10):1750-9. doi: 10.1021/bc4003103. Epub 2013 Sep 20. Bioconjug Chem. 2013. PMID: 24011174 Free PMC article.
SNARE tagging allows stepwise assembly of a multimodular medicinal toxin.
Darios F, Niranjan D, Ferrari E, Zhang F, Soloviev M, Rummel A, Bigalke H, Suckling J, Ushkaryov Y, Naumenko N, Shakirzyanova A, Giniatullin R, Maywood E, Hastings M, Binz T, Davletov B. Darios F, et al. Among authors: niranjan d. Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18197-201. doi: 10.1073/pnas.1007125107. Epub 2010 Oct 4. Proc Natl Acad Sci U S A. 2010. PMID: 20921391 Free PMC article.
Assembly of protein building blocks using a short synthetic peptide.
Ferrari E, Soloviev M, Niranjan D, Arsenault J, Gu C, Vallis Y, O'Brien J, Davletov B. Ferrari E, et al. Among authors: niranjan d. Bioconjug Chem. 2012 Mar 21;23(3):479-84. doi: 10.1021/bc2005208. Epub 2012 Feb 10. Bioconjug Chem. 2012. PMID: 22299630 Free PMC article.
21 results