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Role of (pro)renin receptor in cardiovascular cells from the aspect of signaling.
Hitom H, Liu G, Nishiyama A. Hitom H, et al. Front Biosci (Elite Ed). 2010 Jun 1;2:1246-9. doi: 10.2741/e185. Front Biosci (Elite Ed). 2010. PMID: 20515797 Review.
However, a receptor--the (pro)renin receptor--that binds to both renin and prorenin has been recently identified. Prorenin binding to (pro)renin receptors both results in angiotensinogen cleaving into angiotensin (Ang) I, and triggers activation of (pro)renin receptor-stim …
However, a receptor--the (pro)renin receptor--that binds to both renin and prorenin has been recently identified. Prorenin binding to …
Effects of semotiadil fumarate (SD-3211) on renal hemodynamics and function in dogs.
Nishiyama A, Tamaki T, Masumura H, He H, Kiyomoto H, Aki Y, Yamamoto A, Iwao H, Abe Y. Nishiyama A, et al. Eur J Pharmacol. 1992 Aug 6;218(2-3):311-7. doi: 10.1016/0014-2999(92)90184-6. Eur J Pharmacol. 1992. PMID: 1425946
Intrarenal arterial infusion of semotiadil resulted in a significant increase in renal blood flow (RBF), glomerular filtration rate (GFR), urine flow, urinary excretion of electrolytes and renin release. ...Intrarenal infusion of a potent non-peptide angiotensin II …
Intrarenal arterial infusion of semotiadil resulted in a significant increase in renal blood flow (RBF), glomerular filtration rate ( …
Vasodilation induced by vasopressin V2 receptor stimulation in afferent arterioles.
Tamaki T, Kiyomoto K, He H, Tomohiro A, Nishiyama A, Aki Y, Kimura S, Abe Y. Tamaki T, et al. Kidney Int. 1996 Mar;49(3):722-9. doi: 10.1038/ki.1996.101. Kidney Int. 1996. PMID: 8648913
We microdissected a superficial afferent arteriole with glomerulus from the kidney of a New Zealand White rabbit. Each afferent arteriole was cannulated with a pipette system and microperfused in vitro at 60 mm Hg. ...This vasodilatory effect of AVP was aboli …
We microdissected a superficial afferent arteriole with glomerulus from the kidney of a New Zealand White rabbit. Each afferen …
Effects of KW-3902, a selective and potent adenosine A1 receptor antagonist, on renal hemodynamics and urine formation in anesthetized dogs.
Aki Y, Tomohiro A, Nishiyama A, Kiyomoto K, Kimura S, Abe Y. Aki Y, et al. Pharmacology. 1997 Oct;55(4):193-201. doi: 10.1159/000139528. Pharmacology. 1997. PMID: 9396079
The purpose of the present investigation was to examine the effects of KW-3902 [8-(noradamantan-3-yl)-1,3-dipropyl-xanthine], a selective and potent adenosine A1 receptor antagonist, in order to clarify the role of adenosine in the control of renal hemodynamics and urine f …
The purpose of the present investigation was to examine the effects of KW-3902 [8-(noradamantan-3-yl)-1,3-dipropyl-xanthine], a selec …
Adenosine A(1) receptor antagonist KW-3902 prevents hypoxia-induced renal vasoconstriction.
Nishiyama A, Miyatake A, Aki Y, Fukui T, Rahman M, Kimura S, Abe Y. Nishiyama A, et al. J Pharmacol Exp Ther. 1999 Dec;291(3):988-93. J Pharmacol Exp Ther. 1999. PMID: 10565815
Studies were carried out to determine the intrarenal adenosine production during hypoxia, and the protective effects of a selective adenosine A(1) receptor antagonist 8-(noradamantan-3-yl)-1, 3-dipropylxanthine (KW-3902) on hypoxia-induced renal hemodynamic changes. …
Studies were carried out to determine the intrarenal adenosine production during hypoxia, and the protective effects of a selective a …
Role of nitric oxide in regional blood flow in angiotensin II-induced hypertensive rats.
Nishiyama A, Fujisawa Y, Fukui T, Rahman M, Kondo N, Ogawa Y, Fanzhu L, Guoxing Z, Kimura S, Abe Y. Nishiyama A, et al. Hypertens Res. 2001 Jul;24(4):421-7. doi: 10.1291/hypres.24.421. Hypertens Res. 2001. PMID: 11510755
Effects of angiotensin II on the renal interstitial concentrations of NO2/NO3 and cyclic GMP in anesthetized rats.
Rahman M, Kimura S, Yoneyama H, Kosaka H, Fukui T, Nishiyama A, Abe Y. Rahman M, et al. Jpn J Pharmacol. 2002 Apr;88(4):436-41. doi: 10.1254/jjp.88.436. Jpn J Pharmacol. 2002. PMID: 12046987
The present study was conducted to determine whether exogenous angiotensin II (Ang II) may increase the renal interstitial fluid concentrations of NO2/NO3 (NOx) and cyclic guanosine monophosphate (cGMP) concomitantly and which Ang II receptor subtypes may induce these changes in …
The present study was conducted to determine whether exogenous angiotensin II (Ang II) may increase the renal interstitial fluid concentrati …
Role of adenosine A(1) receptor in angiotensin II- and norepinephrine-induced renal vasoconstriction.
Aki Y, Nishiyama A, Miyatake A, Kimura S, Kohno M, Abe Y. Aki Y, et al. J Pharmacol Exp Ther. 2002 Oct;303(1):117-23. doi: 10.1124/jpet.102.037010. J Pharmacol Exp Ther. 2002. PMID: 12235241
We investigated the contributions of adenosine A(1) receptors to angiotensin II- and norepinephrine-induced renal vasoconstriction. ...These results suggest that basal interstitial adenosine levels influence both angiotensin II and norepinephrine-induced vasoconstriction v …
We investigated the contributions of adenosine A(1) receptors to angiotensin II- and norepinephrine-induced renal vasoconstriction. . …
Role of angiotensin II and reactive oxygen species in cyclosporine A-dependent hypertension.
Nishiyama A, Kobori H, Fukui T, Zhang GX, Yao L, Rahman M, Hitomi H, Kiyomoto H, Shokoji T, Kimura S, Kohno M, Abe Y. Nishiyama A, et al. Hypertension. 2003 Oct;42(4):754-60. doi: 10.1161/01.HYP.0000085195.38870.44. Epub 2003 Jul 21. Hypertension. 2003. PMID: 12874088 Free PMC article.
Treatment with cyclosporine A (CysA), a potent immunosuppressive agent, is associated with systemic and renal vasoconstriction, leading to hypertension. ...Similarly, treatment with a superoxide dismutase mimetic, 4-hydroxy-2,2,6,6,-tetramethylpiperidine-N-ox …
Treatment with cyclosporine A (CysA), a potent immunosuppressive agent, is associated with systemic and renal vasoconstriction …
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