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160 results
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Orally Administered Alpha Lipoic Acid as a Treatment for Geographic Atrophy: A Randomized Clinical Trial.
Kim BJ, Hunter A, Brucker AJ, Hahn P, Gehrs K, Patel A, Edwards AO, Li Y, Khurana RN, Nissim I, Daniel E, Grunwald J, Ying GS, Pistilli M, Maguire MG, Dunaief JL. Kim BJ, et al. Among authors: nissim i. Ophthalmol Retina. 2020 Sep;4(9):889-898. doi: 10.1016/j.oret.2020.03.019. Epub 2020 Apr 2. Ophthalmol Retina. 2020. PMID: 32418846 Free PMC article. Clinical Trial.
Acidosis and astrocyte amino acid metabolism.
Yudkoff M, Daikhin Y, Nissim I, Nissim I. Yudkoff M, et al. Among authors: nissim i. Neurochem Int. 2000 Apr;36(4-5):329-39. doi: 10.1016/s0197-0186(99)00141-2. Neurochem Int. 2000. PMID: 10733000
Intermittent lipid nanoparticle mRNA administration prevents cortical dysmyelination associated with arginase deficiency.
Khoja S, Liu XB, Truong B, Nitzahn M, Lambert J, Eliav A, Nasser E, Randolph E, Burke KE, White R, Zhu X, Martini PGV, Nissim I, Cederbaum SD, Lipshutz GS. Khoja S, et al. Among authors: nissim i. Mol Ther Nucleic Acids. 2022 Apr 27;28:859-874. doi: 10.1016/j.omtn.2022.04.012. eCollection 2022 Jun 14. Mol Ther Nucleic Acids. 2022. PMID: 35694211 Free PMC article.
Gene therapy for guanidinoacetate methyltransferase deficiency restores cerebral and myocardial creatine while resolving behavioral abnormalities.
Khoja S, Lambert J, Nitzahn M, Eliav A, Zhang Y, Tamboline M, Le CT, Nasser E, Li Y, Patel P, Zhuravka I, Lueptow LM, Tkachyova I, Xu S, Nissim I, Schulze A, Lipshutz GS. Khoja S, et al. Among authors: nissim i. Mol Ther Methods Clin Dev. 2022 Mar 28;25:278-296. doi: 10.1016/j.omtm.2022.03.015. eCollection 2022 Jun 9. Mol Ther Methods Clin Dev. 2022. PMID: 35505663 Free PMC article.
Metabolic Enzyme DLST Promotes Tumor Aggression and Reveals a Vulnerability to OXPHOS Inhibition in High-Risk Neuroblastoma.
Anderson NM, Qin X, Finan JM, Lam A, Athoe J, Missiaen R, Skuli N, Kennedy A, Saini AS, Tao T, Zhu S, Nissim I, Look AT, Qing G, Simon MC, Feng H. Anderson NM, et al. Among authors: nissim i. Cancer Res. 2021 Sep 1;81(17):4417-4430. doi: 10.1158/0008-5472.CAN-20-2153. Epub 2021 Jul 7. Cancer Res. 2021. PMID: 34233924 Free PMC article.
160 results