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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 2
1999 3
2001 2
2002 2
2005 2
2006 1
2007 3
2008 9
2009 14
2010 28
2011 15
2012 31
2013 38
2014 22
2015 27
2016 24
2017 24
2018 24
2019 21
2020 7
2021 16
2022 13
2023 6
2024 14
2025 12
2026 4

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287 results

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Page 1
Drug Repurposing: Conversion of the Peripherally Restricted HIV Protease Inhibitor Amprenavir to Potent, Selective, and CNS-Penetrant Agonists for the Cannabinoid Receptor 2.
Haymer DH, Duncan RA, Rodriguez AL, Han A, Lindsay RJ, Wijesiri NK, Thompson Gray A, Krishnan S, Qi A, Brown BP, Boutaud O, Engers DW, Jones CK, Niswender CM, Lindsley CW, Bender AM. Haymer DH, et al. Among authors: niswender cm. J Med Chem. 2026 Feb 26;69(4):4187-4207. doi: 10.1021/acs.jmedchem.5c02796. Epub 2026 Feb 5. J Med Chem. 2026. PMID: 41642702 Free PMC article.
Discovery of 7-(Pyridin-3-yl)thieno[3,2-b]pyridine-5-carboxamides as Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5.
Henderson SH, Ringuette AE, Whomble DL, Capstick RA, Richardson AE, Maurer MA, Billard NB, Lei X, Wilkinson JC, Kethanapalli SH, Cho HP, Rodriguez AL, Niswender CM, Peng W, Rook JM, Chang S, Blobaum AL, Boutaud O, Felts AS, Conn PJ, Lindsley CW, Temple KJ. Henderson SH, et al. Among authors: niswender cm. ACS Chem Neurosci. 2026 Feb 4;17(3):610-623. doi: 10.1021/acschemneuro.5c00896. Epub 2026 Jan 25. ACS Chem Neurosci. 2026. PMID: 41582453 Free PMC article.
Discovery of VU6025733 (AG06827): A Highly Selective, Orally Bioavailable, and Structurally Distinct M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust In Vivo Efficacy.
Gregro AR, Park C, Long MF, Baker LA, Bollinger KA, Ringuette AE, Peng L, Luscombe VB, Billard NB, Rodriguez AL, Niswender CM, Peng W, Dickerson JW, Rook JM, O'Neill J, Chang S, Boonen HCM, Jensen T, Thomsen MS, Bridges TM, Boutaud O, Conn PJ, Engers DW, Lindsley CW, Temple KJ. Gregro AR, et al. Among authors: niswender cm. ACS Chem Neurosci. 2026 Feb 4;17(3):649-665. doi: 10.1021/acschemneuro.5c00963. Epub 2026 Jan 25. ACS Chem Neurosci. 2026. PMID: 41581069 Free PMC article.
Discovery of a Novel sp3‑Rich M1 Positive Allosteric Modulators (PAMs) Chemotype via Scaffold Hopping.
Bungard JD, Spearing P, Nishio Y, Rathnayake U, Presley CC, Chang S, Kling HE, Thompson AD, Cho HP, Peng L, Rodriguez AL, Niswender CM, Boutaud O, Kramlinger V, Jones CK, Conn PJ, Engers JL, Engers DW, Lindsley CW, Han C. Bungard JD, et al. Among authors: niswender cm. ACS Med Chem Lett. 2025 Jun 17;16(7):1231-1238. doi: 10.1021/acsmedchemlett.5c00271. eCollection 2025 Jul 10. ACS Med Chem Lett. 2025. PMID: 40666451
Overexpression of mGlu7B in Mice: Implications for Neurodevelopmental Disorders.
Freitas GA, Weiss K, Bavadekar V, Vermudez SAD, Fisher NM, Buch A, Dogra S, Xiang Z, Gogliotti RG, Niswender CM. Freitas GA, et al. Among authors: niswender cm. Mol Neurobiol. 2025 Nov;62(11):14015-14031. doi: 10.1007/s12035-025-05183-y. Epub 2025 Jul 10. Mol Neurobiol. 2025. PMID: 40637957 Free PMC article.
287 results