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Nitric oxide prevents aortic neointimal hyperplasia by controlling macrophage polarization.
Lavin B, Gómez M, Pello OM, Castejon B, Piedras MJ, Saura M, Zaragoza C. Lavin B, et al. Arterioscler Thromb Vasc Biol. 2014 Aug;34(8):1739-46. doi: 10.1161/ATVBAHA.114.303866. Epub 2014 Jun 12. Arterioscler Thromb Vasc Biol. 2014. PMID: 24925976
OBJECTIVE: Nitric oxide synthase 3 (NOS3) prevents neointima hyperplasia by still unknown mechanisms. To demonstrate the significance of endothelial nitric oxide in the polarization of infiltrated macrophages through the expression …
OBJECTIVE: Nitric oxide synthase 3 (NOS3) prevents neointima hyperplasia by still unknown mechanisms. To demonst …
Zn(2+)-dependent suppression of vascular smooth muscle intimal hyperplasia from biodegradable zinc implants.
Guillory RJ 2nd, Kolesar TM, Oliver AA, Stuart JA, Bocks ML, Drelich JW, Goldman J. Guillory RJ 2nd, et al. Mater Sci Eng C Mater Biol Appl. 2020 Jun;111:110826. doi: 10.1016/j.msec.2020.110826. Epub 2020 Mar 7. Mater Sci Eng C Mater Biol Appl. 2020. PMID: 32279804 Free PMC article.
In this report, we show that zinc-containing materials can be used to prevent neointimal formation when implanted into the rat aorta. Indeed, neointimal cells were significantly more TUNEL positive and alpha-actin negative at the interface of biodegrad …
In this report, we show that zinc-containing materials can be used to prevent neointimal formation when implanted into the rat …