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Nitric oxide signalling in the brain and its control of bodily functions.
Chachlaki K, Prevot V. Chachlaki K, et al. Br J Pharmacol. 2020 Dec;177(24):5437-5458. doi: 10.1111/bph.14800. Epub 2019 Sep 8. Br J Pharmacol. 2020. PMID: 31347144 Free PMC article. Review.
Nitric oxide (NO) is a versatile molecule that plays key roles in the development and survival of mammalian species by endowing brain neuronal networks with the ability to make continual adjustments to function in response to moment-to-moment changes i
Nitric oxide (NO) is a versatile molecule that plays key roles in the development and survival of mammalian species by endowin
Nitric oxide and homeostatic control: an intercellular signalling molecule contributing to autonomic and neuroendocrine integration?
Stern JE. Stern JE. Prog Biophys Mol Biol. 2004 Feb-Apr;84(2-3):197-215. doi: 10.1016/j.pbiomolbio.2003.11.015. Prog Biophys Mol Biol. 2004. PMID: 14769436 Free article. Review.
Accumulated evidence indicates that nitric oxide (NO) plays a pivotal role in the central control of bodily homeostasis, including cardiovascular and fluid balance regulation. ...We propose that this dynamic NO signaling mechanisms may constitut …
Accumulated evidence indicates that nitric oxide (NO) plays a pivotal role in the central control of bodily home …
Phenotyping of nNOS neurons in the postnatal and adult female mouse hypothalamus.
Chachlaki K, Malone SA, Qualls-Creekmore E, Hrabovszky E, Münzberg H, Giacobini P, Ango F, Prevot V. Chachlaki K, et al. J Comp Neurol. 2017 Oct 15;525(15):3177-3189. doi: 10.1002/cne.24257. Epub 2017 Jun 19. J Comp Neurol. 2017. PMID: 28577305 Free PMC article.
Neurons expressing nitric oxide (NO) synthase (nNOS) and thus capable of synthesizing NO play major roles in many aspects of brain function. ...In both adults and neonates, nNOS was largely restricted to regions of the hypothalamus involved in the c
Neurons expressing nitric oxide (NO) synthase (nNOS) and thus capable of synthesizing NO play major roles in many aspects of …
Leptin action through hypothalamic nitric oxide synthase-1-expressing neurons controls energy balance.
Leshan RL, Greenwald-Yarnell M, Patterson CM, Gonzalez IE, Myers MG Jr. Leshan RL, et al. Nat Med. 2012 May;18(5):820-3. doi: 10.1038/nm.2724. Nat Med. 2012. PMID: 22522563 Free PMC article.
Few effective measures exist to combat the worldwide obesity epidemic(1), and the identification of potential therapeutic targets requires a deeper understanding of the mechanisms that control energy balance. Leptin, an adipocyte-derived hormone that signals the lon …
Few effective measures exist to combat the worldwide obesity epidemic(1), and the identification of potential therapeutic targets requires a …
alpha-Synuclein enhances secretion and toxicity of amyloid beta peptides in PC12 cells.
Kazmierczak A, Strosznajder JB, Adamczyk A. Kazmierczak A, et al. Neurochem Int. 2008 Dec;53(6-8):263-9. doi: 10.1016/j.neuint.2008.08.004. Epub 2008 Aug 29. Neurochem Int. 2008. PMID: 18804502
In contrast Z-DEVD-FMK and cyclosporine A were ineffective in APPsw cells containing elevated amount of amyloid beta treated with alpha-synuclein. It was found that the inhibition of neuronal and inducible nitric oxide synthase reversed the toxic effect of alpha-syn …
In contrast Z-DEVD-FMK and cyclosporine A were ineffective in APPsw cells containing elevated amount of amyloid beta treated with alpha-synu …