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Indoxyl sulfate, a uremic toxin, promotes cell senescence in aorta of hypertensive rats.
Adijiang A, Higuchi Y, Nishijima F, Shimizu H, Niwa T. Adijiang A, et al. Among authors: niwa t. Biochem Biophys Res Commun. 2010 Sep 3;399(4):637-41. doi: 10.1016/j.bbrc.2010.07.130. Epub 2010 Aug 4. Biochem Biophys Res Commun. 2010. PMID: 20691162
Indole-3-propionic acid suppresses indoxyl sulfate-induced expression of fibrotic and inflammatory genes in proximal tubular cells.
Yisireyili M, Takeshita K, Saito S, Murohara T, Niwa T. Yisireyili M, et al. Among authors: niwa t. Nagoya J Med Sci. 2017 Nov;79(4):477-486. doi: 10.18999/nagjms.79.4.477. Nagoya J Med Sci. 2017. PMID: 29238104 Free PMC article.
Indoxyl sulfate upregulates prorenin expression via nuclear factor-κB p65, signal transducer and activator of transcription 3, and reactive oxygen species in proximal tubular cells.
Saito S, Yisireyili M, Shimizu H, Ng HY, Niwa T. Saito S, et al. Among authors: niwa t. J Ren Nutr. 2015 Mar;25(2):145-8. doi: 10.1053/j.jrn.2014.10.008. Epub 2014 Dec 31. J Ren Nutr. 2015. PMID: 25556305
Indoxyl sulfate induces nephrovascular senescence.
Niwa T, Shimizu H. Niwa T, et al. J Ren Nutr. 2012 Jan;22(1):102-6. doi: 10.1053/j.jrn.2011.10.032. J Ren Nutr. 2012. PMID: 22200425 Review.
Relation of plasma indoxyl sulfate levels and estimated glomerular filtration rate to left ventricular diastolic dysfunction.
Sato B, Yoshikawa D, Ishii H, Suzuki S, Inoue Y, Takeshita K, Tanaka M, Kumagai S, Matsumoto M, Okumura S, Hayashi M, Matsubara T, Niwa T, Murohara T. Sato B, et al. Among authors: niwa t. Am J Cardiol. 2013 Mar 1;111(5):712-6. doi: 10.1016/j.amjcard.2012.11.025. Epub 2012 Dec 8. Am J Cardiol. 2013. PMID: 23228923
Indoxyl sulfate induces epithelial-to-mesenchymal transition in rat kidneys and human proximal tubular cells.
Bolati D, Shimizu H, Higashiyama Y, Nishijima F, Niwa T. Bolati D, et al. Among authors: niwa t. Am J Nephrol. 2011;34(4):318-23. doi: 10.1159/000330852. Epub 2011 Aug 18. Am J Nephrol. 2011. PMID: 21849772
Update of uremic toxin research by mass spectrometry.
Niwa T. Niwa T. Mass Spectrom Rev. 2011 May-Jun;30(3):510-21. doi: 10.1002/mas.20323. Epub 2011 Feb 16. Mass Spectrom Rev. 2011. PMID: 21328600 Review.
Removal of protein-bound uraemic toxins by haemodialysis.
Niwa T. Niwa T. Blood Purif. 2013;35 Suppl 2:20-5. doi: 10.1159/000350843. Epub 2013 May 3. Blood Purif. 2013. PMID: 23676831 Review.
Indoxyl sulfate and atherosclerotic risk factors in hemodialysis patients.
Taki K, Tsuruta Y, Niwa T. Taki K, et al. Among authors: niwa t. Am J Nephrol. 2007;27(1):30-5. doi: 10.1159/000098542. Epub 2007 Jan 11. Am J Nephrol. 2007. PMID: 17215572
Effects of oral adsorbent on gene expression profile in uremic rat kidney: cDNA array analysis.
Aoyama I, Enomoto A, Niwa T. Aoyama I, et al. Among authors: niwa t. Am J Kidney Dis. 2003 Mar;41(3 Suppl 1):S8-14. doi: 10.1053/ajkd.2003.50075. Am J Kidney Dis. 2003. PMID: 12612943
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