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Discovery of Clinical Candidate AZD5462, a Selective Oral Allosteric RXFP1 Agonist for Treatment of Heart Failure.
Granberg KL, Sakamaki S, Larsson N, Bergström F, Fuchigami R, Niwa Y, Ryberg E, Backmark A, Kato H, Miyazaki S, Iguchi K, Sakamoto T, Persson M, Idei A, Prieto Garcia L, Villar IC, Gradén H, Bergonzini G, Arvidsson T, Fujita T, Althage M, Ulander J, Kimura J, Yoneda H, Fjellström O, Mochida H, Lal M. Granberg KL, et al. Among authors: niwa y. J Med Chem. 2024 Mar 28;67(6):4419-4441. doi: 10.1021/acs.jmedchem.3c02184. Epub 2024 Mar 19. J Med Chem. 2024. PMID: 38502782
Identification of Novel Series of Potent and Selective Relaxin Family Peptide Receptor 1 (RXFP1) Agonists.
Granberg KL, Sakamaki S, Fuchigami R, Niwa Y, Fujio M, Kato H, Bergström F, Larsson N, Persson M, Villar IC, Fujita T, Sugikawa E, Althage M, Yano N, Yokoyama Y, Kimura J, Lal M, Mochida H. Granberg KL, et al. Among authors: niwa y. J Med Chem. 2024 Mar 28;67(6):4442-4462. doi: 10.1021/acs.jmedchem.3c02183. Epub 2024 Mar 19. J Med Chem. 2024. PMID: 38502780
Correction: Modulation of serotonin in the gut-liver neural axis ameliorates the fatty and fibrotic changes in non-alcoholic fatty liver.
Ko M, Kamimura K, Owaki T, Nagoya T, Sakai N, Nagayama I, Niwa Y, Shibata O, Oda C, Morita S, Kimura A, Inoue R, Setsu T, Sakamaki A, Yokoo T, Terai S. Ko M, et al. Among authors: niwa y. Dis Model Mech. 2023 Dec 1;16(12):dmm050622. doi: 10.1242/dmm.050622. Epub 2023 Nov 30. Dis Model Mech. 2023. PMID: 38032301 Free PMC article. No abstract available.
Transvenous Radiofrequency Catheter Ablation for an Aldosterone-Producing Tumor of the Left Adrenal Gland: A First in Human Case Report.
Oguro S, Ota H, Yanagaki S, Kawabata M, Kamada H, Omata K, Tezuka Y, Ono Y, Morimoto R, Satoh F, Toyama H, Tanimoto K, Konno D, Yamauchi M, Niwa Y, Miyamoto H, Mori K, Tanaka T, Ishihata H, Takase K. Oguro S, et al. Among authors: niwa y. Cardiovasc Intervent Radiol. 2023 Dec;46(12):1666-1673. doi: 10.1007/s00270-023-03584-x. Epub 2023 Nov 16. Cardiovasc Intervent Radiol. 2023. PMID: 37973663 Free PMC article.
957 results