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86 results
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Cytochrome p450 retinoic acid 4-hydroxylase inhibitors: potential agents for cancer therapy.
Njar VC. Njar VC. Mini Rev Med Chem. 2002 Jun;2(3):261-9. doi: 10.2174/1389557023406223. Mini Rev Med Chem. 2002. PMID: 12370067 Review.
CYP17 inhibitors for prostate cancer treatment--an update.
Moreira VM, Salvador JA, Vasaitis TS, Njar VC. Moreira VM, et al. Among authors: njar vc. Curr Med Chem. 2008;15(9):868-99. doi: 10.2174/092986708783955428. Curr Med Chem. 2008. PMID: 18473796 Review.
Novel retinoic acid metabolism blocking agents have potent inhibitory activities on human breast cancer cells and tumour growth.
Patel JB, Mehta J, Belosay A, Sabnis G, Khandelwal A, Brodie AM, Soprano DR, Njar VC. Patel JB, et al. Among authors: njar vc. Br J Cancer. 2007 Apr 23;96(8):1204-15. doi: 10.1038/sj.bjc.6603705. Epub 2007 Mar 27. Br J Cancer. 2007. PMID: 17387344 Free PMC article.
Inhibitory effects of retinoic acid metabolism blocking agents (RAMBAs) on the growth of human prostate cancer cells and LNCaP prostate tumour xenografts in SCID mice.
Huynh CK, Brodie AM, Njar VC. Huynh CK, et al. Among authors: njar vc. Br J Cancer. 2006 Feb 27;94(4):513-23. doi: 10.1038/sj.bjc.6602971. Br J Cancer. 2006. PMID: 16449997 Free PMC article.
MS-275 synergistically enhances the growth inhibitory effects of RAMBA VN/66-1 in hormone-insensitive PC-3 prostate cancer cells and tumours.
Khandelwal A, Gediya L, Njar V. Khandelwal A, et al. Br J Cancer. 2008 Apr 8;98(7):1234-43. doi: 10.1038/sj.bjc.6604295. Epub 2008 Mar 18. Br J Cancer. 2008. PMID: 18349838 Free PMC article.
Aromatase inhibitors in advanced breast cancer: mechanism of action and clinical implications.
Brodie AM, Njar VC. Brodie AM, et al. Among authors: njar vc. J Steroid Biochem Mol Biol. 1998 Jul;66(1-2):1-10. doi: 10.1016/s0960-0760(98)00022-3. J Steroid Biochem Mol Biol. 1998. PMID: 9712406 Review. No abstract available.
Pregnenolone stimulates LNCaP prostate cancer cell growth via the mutated androgen receptor.
Grigoryev DN, Long BJ, Njar VC, Brodie AH. Grigoryev DN, et al. Among authors: njar vc. J Steroid Biochem Mol Biol. 2000 Dec 1;75(1):1-10. doi: 10.1016/s0960-0760(00)00131-x. J Steroid Biochem Mol Biol. 2000. PMID: 11179903
Potent inhibition of retinoic acid metabolism enzyme(s) by novel azolyl retinoids.
Njar VC, Nnane IP, Brodie AM. Njar VC, et al. Bioorg Med Chem Lett. 2000 Sep 4;10(17):1905-8. doi: 10.1016/s0960-894x(00)00391-7. Bioorg Med Chem Lett. 2000. PMID: 10987414
Effects of novel 17-azolyl compounds on androgen synthesis in vitro and in vivo.
Nnane IP, Njar VC, Liu Y, Lu Q, Brodie AM. Nnane IP, et al. Among authors: njar vc. J Steroid Biochem Mol Biol. 1999 Dec 15;71(3-4):145-52. doi: 10.1016/s0960-0760(99)00129-6. J Steroid Biochem Mol Biol. 1999. PMID: 10659703
Effects of new 17alpha-hydroxylase/C(17,20)-lyase inhibitors on LNCaP prostate cancer cell growth in vitro and in vivo.
Grigoryev DN, Long BJ, Nnane IP, Njar VC, Liu Y, Brodie AM. Grigoryev DN, et al. Among authors: njar vc. Br J Cancer. 1999 Oct;81(4):622-30. doi: 10.1038/sj.bjc.6690739. Br J Cancer. 1999. PMID: 10574247 Free PMC article.
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