No JH - Search Results

1

Lipophilic bisphosphonates are potent inhibitors of Plasmodium liver-stage growth.

Singh AP, Zhang Y, No JH, Docampo R, Nussenzweig V, Oldfield E. Singh AP, et al. Among authors: no jh. Antimicrob Agents Chemother. 2010 Jul;54(7):2987-93. doi: 10.1128/AAC.00198-10. Epub 2010 May 10. Antimicrob Agents Chemother. 2010. PMID: 20457823 Free PMC article.

2

Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation.

K-M Chen C, Hudock MP, Zhang Y, Guo RT, Cao R, No JH, Liang PH, Ko TP, Chang TH, Chang SC, Song Y, Axelson J, Kumar A, Wang AH, Oldfield E. K-M Chen C, et al. Among authors: no jh. J Med Chem. 2008 Sep 25;51(18):5594-607. doi: 10.1021/jm800325y. J Med Chem. 2008. PMID: 18800762 Free PMC article.

3

Bisphosphonate inhibition of a Plasmodium farnesyl diphosphate synthase and a general method for predicting cell-based activity from enzyme data.

Mukkamala D, No JH, Cass LM, Chang TK, Oldfield E. Mukkamala D, et al. Among authors: no jh. J Med Chem. 2008 Dec 25;51(24):7827-33. doi: 10.1021/jm8009074. J Med Chem. 2008. PMID: 19053772 Free PMC article.

4

Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation.

Zhang Y, Cao R, Yin F, Hudock MP, Guo RT, Krysiak K, Mukherjee S, Gao YG, Robinson H, Song Y, No JH, Bergan K, Leon A, Cass L, Goddard A, Chang TK, Lin FY, Van Beek E, Papapoulos S, Wang AH, Kubo T, Ochi M, Mukkamala D, Oldfield E. Zhang Y, et al. Among authors: no jh. J Am Chem Soc. 2009 Apr 15;131(14):5153-62. doi: 10.1021/ja808285e. J Am Chem Soc. 2009. PMID: 19309137 Free PMC article.

5

Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results.

Song Y, Liu CI, Lin FY, No JH, Hensler M, Liu YL, Jeng WY, Low J, Liu GY, Nizet V, Wang AH, Oldfield E. Song Y, et al. Among authors: no jh. J Med Chem. 2009 Jul 9;52(13):3869-80. doi: 10.1021/jm9001764. J Med Chem. 2009. PMID: 19456099 Free PMC article.

6

Lipophilic pyridinium bisphosphonates: potent gammadelta T cell stimulators.

Zhang Y, Cao R, Yin F, Lin FY, Wang H, Krysiak K, No JH, Mukkamala D, Houlihan K, Li J, Morita CT, Oldfield E. Zhang Y, et al. Among authors: no jh. Angew Chem Int Ed Engl. 2010 Feb 1;49(6):1136-8. doi: 10.1002/anie.200905933. Angew Chem Int Ed Engl. 2010. PMID: 20039246 Free PMC article. No abstract available.

7

Bioorganometallic mechanism of action, and inhibition, of IspH.

Wang W, Wang K, Liu YL, No JH, Li J, Nilges MJ, Oldfield E. Wang W, et al. Among authors: no jh. Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4522-7. doi: 10.1073/pnas.0911087107. Epub 2010 Feb 19. Proc Natl Acad Sci U S A. 2010. PMID: 20173096 Free PMC article.

8

Inhibition of the Fe(4)S(4)-cluster-containing protein IspH (LytB): electron paramagnetic resonance, metallacycles, and mechanisms.

Wang K, Wang W, No JH, Zhang Y, Zhang Y, Oldfield E. Wang K, et al. Among authors: no jh. J Am Chem Soc. 2010 May 19;132(19):6719-27. doi: 10.1021/ja909664j. J Am Chem Soc. 2010. PMID: 20426416 Free PMC article.

9

Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity.

No JH, de Macedo Dossin F, Zhang Y, Liu YL, Zhu W, Feng X, Yoo JA, Lee E, Wang K, Hui R, Freitas-Junior LH, Oldfield E. No JH, et al. Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4058-63. doi: 10.1073/pnas.1118215109. Epub 2012 Mar 5. Proc Natl Acad Sci U S A. 2012. PMID: 22392982 Free PMC article.

10

Chemo-Immunotherapeutic Anti-Malarials Targeting Isoprenoid Biosynthesis.

Zhang Y, Zhu W, Liu YL, Wang H, Wang K, Li K, No JH, Ayong L, Gulati A, Pang R, Freitas-Junior L, Morita CT, Old-Field E. Zhang Y, et al. Among authors: no jh. ACS Med Chem Lett. 2013 Apr 11;4(4):423-427. doi: 10.1021/ml4000436. ACS Med Chem Lett. 2013. PMID: 23610597 Free PMC article.

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