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Structure-based discovery of cyclin-dependent protein kinase inhibitors.
Martin MP, Endicott JA, Noble MEM. Martin MP, et al. Among authors: Noble MEM. Essays Biochem. 2017 Nov 8;61(5):439-452. doi: 10.1042/EBC20170040. Print 2017 Nov 8. Essays Biochem. 2017. PMID: 29118092 Free PMC article. Review.
Comparative structural and functional studies of 4-(thiazol-5-yl)-2-(phenylamino)pyrimidine-5-carbonitrile CDK9 inhibitors suggest the basis for isotype selectivity.
Hole AJ, Baumli S, Shao H, Shi S, Huang S, Pepper C, Fischer PM, Wang S, Endicott JA, Noble ME. Hole AJ, et al. Among authors: Noble ME. J Med Chem. 2013 Feb 14;56(3):660-70. doi: 10.1021/jm301495v. Epub 2013 Jan 29. J Med Chem. 2013. PMID: 23252711 Free PMC article.
Structure of arylamine N-acetyltransferase reveals a catalytic triad.
Sinclair JC, Sandy J, Delgoda R, Sim E, Noble ME. Sinclair JC, et al. Among authors: Noble ME. Nat Struct Biol. 2000 Jul;7(7):560-4. doi: 10.1038/76783. Nat Struct Biol. 2000. PMID: 10876241
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