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Peptide intra-tumor injection for cancer immunotherapy: enhancement of tumor cell antigenicity is a novel and attractive strategy.
Nobuoka D, Yoshikawa T, Fujiwara T, Nakatsura T. Nobuoka D, et al. Hum Vaccin Immunother. 2013 Jun;9(6):1234-6. doi: 10.4161/hv.23990. Epub 2013 Feb 14. Hum Vaccin Immunother. 2013. PMID: 23411443 Free PMC article. Review.
Phase I trial of a glypican-3-derived peptide vaccine for advanced hepatocellular carcinoma: immunologic evidence and potential for improving overall survival.
Sawada Y, Yoshikawa T, Nobuoka D, Shirakawa H, Kuronuma T, Motomura Y, Mizuno S, Ishii H, Nakachi K, Konishi M, Nakagohri T, Takahashi S, Gotohda N, Takayama T, Yamao K, Uesaka K, Furuse J, Kinoshita T, Nakatsura T. Sawada Y, et al. Among authors: nobuoka d. Clin Cancer Res. 2012 Jul 1;18(13):3686-96. doi: 10.1158/1078-0432.CCR-11-3044. Epub 2012 May 10. Clin Cancer Res. 2012. PMID: 22577059 Clinical Trial.
Detection and preliminary evaluation of circulating tumor cells in the peripheral blood of patients with eight types of cancer using a telomerase-specific adenovirus.
Yabusaki M, Sato J, Kohyama A, Kojima T, Nobuoka D, Yoshikawa T, Sawada Y, Murakami K, Gohda K, Okegawa T, Nakamura M, Takamatsu K, Ito M, Kaneko K, Nakatsura T. Yabusaki M, et al. Among authors: nobuoka d. Oncol Rep. 2014 Nov;32(5):1772-8. doi: 10.3892/or.2014.3436. Epub 2014 Aug 22. Oncol Rep. 2014. PMID: 25176113 Free PMC article.
Higher human lymphocyte antigen class I expression in early-stage cancer cells leads to high sensitivity for cytotoxic T lymphocytes.
Akazawa Y, Nobuoka D, Takahashi M, Yoshikawa T, Shimomura M, Mizuno S, Fujiwara T, Nakamoto Y, Nakatsura T. Akazawa Y, et al. Among authors: nobuoka d. Cancer Sci. 2019 Jun;110(6):1842-1852. doi: 10.1111/cas.14022. Epub 2019 May 18. Cancer Sci. 2019. PMID: 30973665 Free PMC article.
Phase II study of the GPC3-derived peptide vaccine as an adjuvant therapy for hepatocellular carcinoma patients.
Sawada Y, Yoshikawa T, Ofuji K, Yoshimura M, Tsuchiya N, Takahashi M, Nobuoka D, Gotohda N, Takahashi S, Kato Y, Konishi M, Kinoshita T, Ikeda M, Nakachi K, Yamazaki N, Mizuno S, Takayama T, Yamao K, Uesaka K, Furuse J, Endo I, Nakatsura T. Sawada Y, et al. Among authors: nobuoka d. Oncoimmunology. 2016 Jan 19;5(5):e1129483. doi: 10.1080/2162402X.2015.1129483. eCollection 2016 May. Oncoimmunology. 2016. PMID: 27467945 Free PMC article.
Analysis of cytotoxic T lymphocytes from a patient with hepatocellular carcinoma who showed a clinical response to vaccination with a glypican‑3‑derived peptide.
Tada Y, Yoshikawa T, Shimomura M, Sawada Y, Sakai M, Shirakawa H, Nobuoka D, Nakatsura T. Tada Y, et al. Among authors: nobuoka d. Int J Oncol. 2013 Oct;43(4):1019-26. doi: 10.3892/ijo.2013.2044. Epub 2013 Jul 31. Int J Oncol. 2013. PMID: 23903757 Free PMC article.
Remarkable tumor lysis in a hepatocellular carcinoma patient immediately following glypican-3-derived peptide vaccination: an autopsy case.
Sawada Y, Yoshikawa T, Fujii S, Mitsunaga S, Nobuoka D, Mizuno S, Takahashi M, Yamauchi C, Endo I, Nakatsura T. Sawada Y, et al. Among authors: nobuoka d. Hum Vaccin Immunother. 2013 Jun;9(6):1228-33. doi: 10.4161/hv.24179. Epub 2013 Mar 6. Hum Vaccin Immunother. 2013. PMID: 23466818 Free PMC article.
Peptide vaccines for hepatocellular carcinoma.
Nobuoka D, Yoshikawa T, Sawada Y, Fujiwara T, Nakatsura T. Nobuoka D, et al. Hum Vaccin Immunother. 2013 Jan;9(1):210-2. doi: 10.4161/hv.22473. Hum Vaccin Immunother. 2013. PMID: 23442593 Free PMC article.
Identification of an H2-Kb or H2-Db restricted and glypican-3-derived cytotoxic T-lymphocyte epitope peptide.
Iwama T, Horie K, Yoshikawa T, Nobuoka D, Shimomura M, Sawada Y, Nakatsura T. Iwama T, et al. Among authors: nobuoka d. Int J Oncol. 2013 Mar;42(3):831-8. doi: 10.3892/ijo.2013.1793. Epub 2013 Jan 23. Int J Oncol. 2013. PMID: 23354275 Free PMC article.
Intratumoral peptide injection enhances tumor cell antigenicity recognized by cytotoxic T lymphocytes: a potential option for improvement in antigen-specific cancer immunotherapy.
Nobuoka D, Yoshikawa T, Takahashi M, Iwama T, Horie K, Shimomura M, Suzuki S, Sakemura N, Nakatsugawa M, Sadamori H, Yagi T, Fujiwara T, Nakatsura T. Nobuoka D, et al. Cancer Immunol Immunother. 2013 Apr;62(4):639-52. doi: 10.1007/s00262-012-1366-6. Epub 2012 Nov 11. Cancer Immunol Immunother. 2013. PMID: 23143746 Free PMC article.
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