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PD-Like Pathogenesis in Caenorhabditis elegans Intestinally Infected with Nocardia farcinica and the Underlying Molecular Mechanisms.
Liu W, Zhou W, Zhao P, Wu T, Gu H, Li Y, Zhong C, Bai H, Zhao N, Huang X. Liu W, et al. Mol Neurobiol. 2024 Mar 28. doi: 10.1007/s12035-024-04076-w. Online ahead of print. Mol Neurobiol. 2024. PMID: 38546929
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the abnormal aggregation of alpha-synuclein (alpha-syn) and the loss of dopaminergic neurons. ...Here, we found that intestinal infection with Nocardia farcinica induced a series …
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the abnormal aggregation of alpha-synuclein ( …
Nocardia cyriacigeorgica Elicits Gut Disturbances in a Leaky Gut Model of Colitis, but Not the Harmful Cascade Leading to Gut-First Parkinson's Disease.
Magalhães JD, Candeias E, Melo-Marques I, Abreu AE, Pereira-Santos AR, Esteves AR, Cardoso SM, Empadinhas N. Magalhães JD, et al. Int J Mol Sci. 2024 Mar 18;25(6):3423. doi: 10.3390/ijms25063423. Int J Mol Sci. 2024. PMID: 38542396 Free PMC article.
Parkinson's disease (PD) is a progressive neurodegenerative disorder with an unknown cause. ...As mitochondria are derived from ancestral alpha-proteobacteria, other bacteria may specifically target this organelle. We sought to use Nocardia cyriacigeor …
Parkinson's disease (PD) is a progressive neurodegenerative disorder with an unknown cause. ...As mitochondria are deri …
Molecular, cellular and neurological consequences of infection by the neglected human pathogen Nocardia.
Ji X, Han L, Zhang W, Sun L, Xu S, Qiu X, Fan S, Li Z. Ji X, et al. BMC Biol. 2022 Nov 9;20(1):251. doi: 10.1186/s12915-022-01452-7. BMC Biol. 2022. PMID: 36352407 Free PMC article.
BACKGROUND: Nocardia is a facultative intracellular pathogen that infects the lungs and brains of immunocompromised patients with consequences that can be fatal. ...In our mouse model, Nocardia infection led to neurological symptoms and we found that 15 of 22 Noc …
BACKGROUND: Nocardia is a facultative intracellular pathogen that infects the lungs and brains of immunocompromised patients with con …
Virulence test using nematodes to prescreen Nocardia species capable of inducing neurodegeneration and behavioral disorders.
Bernardin Souibgui C, Zoropogui A, Voisin J, Ribun S, Vasselon V, Pujic P, Rodriguez-Nava V, Belly P, Cournoyer B, Blaha D. Bernardin Souibgui C, et al. PeerJ. 2017 Oct 10;5:e3823. doi: 10.7717/peerj.3823. eCollection 2017. PeerJ. 2017. PMID: 29038748 Free PMC article.
BACKGROUND: Parkinson's disease (PD) is a disorder characterized by dopaminergic neuron programmed cell death. ...Some studies have highlighted the ability of N. cyriacigeorgica to induce Parkinson's disease-like symptoms in animals. Acti …
BACKGROUND: Parkinson's disease (PD) is a disorder characterized by dopaminergic neuron programmed cell death. ...Some …
M. paratuberculosis and Parkinson's disease--is this a trigger.
Dow CT. Dow CT. Med Hypotheses. 2014 Dec;83(6):709-12. doi: 10.1016/j.mehy.2014.09.025. Epub 2014 Oct 14. Med Hypotheses. 2014. PMID: 25459140
Mycobacterium avium ss. paratuberculosis (MAP) causes Johne's disease, an important enteric inflammatory disease mostly studied in ruminant animals. ...Genetic studies reveal an association between Parkinson's disease (PD), leprosy and Crohn's …
Mycobacterium avium ss. paratuberculosis (MAP) causes Johne's disease, an important enteric inflammatory disease mostly studie …
Natural toxins implicated in the development of Parkinson's disease.
Salama M, Arias-Carrión O. Salama M, et al. Ther Adv Neurol Disord. 2011 Nov;4(6):361-73. doi: 10.1177/1756285611413004. Ther Adv Neurol Disord. 2011. PMID: 22164190 Free PMC article.
Experimental models of Parkinson's disease (PD) are of great importance for improving the design of future clinical trials. ...Here, we discuss some toxins of natural origin (e.g. cycad-derived toxins, epoxomicin, Nocardia asteroides bacteria, Streptom …
Experimental models of Parkinson's disease (PD) are of great importance for improving the design of future clinical tri …
Filterable forms of Nocardia: a preferential site of infection in the mouse brain.
Kohbata S, Emura S, Kadoya C. Kohbata S, et al. Microbes Infect. 2009 Jul-Aug;11(8-9):744-52. doi: 10.1016/j.micinf.2009.04.013. Epub 2009 Apr 17. Microbes Infect. 2009. PMID: 19376258 Free article.
Filterable forms of Nocardia (i.e., filterable nocardiae) are characterized as spherical structures containing many granules. ...An accumulation of acid-fast lipochrome bodies, similar to filterable nocardiae, is observed in glial cells of the midbrain nigral …
Filterable forms of Nocardia (i.e., filterable nocardiae) are characterized as spherical structures containing many granules. …
Lack of evidence for Nocardia asteroides in brain specimens from Lewy body-containing disorders.
Lu L, Camp DM, Loeffler DA, LeWitt PA. Lu L, et al. Microb Pathog. 2005 Nov-Dec;39(5-6):205-11. doi: 10.1016/j.micpath.2005.08.001. Epub 2005 Oct 28. Microb Pathog. 2005. PMID: 16257505
Previous studies have suggested that Nocardia asteroides may play a role in the pathogenesis of Parkinson's disease (PD), including the production of Lewy bodies, the inclusion bodies present in this disorder. ...These findings do not support an associ …
Previous studies have suggested that Nocardia asteroides may play a role in the pathogenesis of Parkinson's disease …
21 results