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OTX015 (MK-8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models.
Berenguer-Daizé C, Astorgues-Xerri L, Odore E, Cayol M, Cvitkovic E, Noel K, Bekradda M, MacKenzie S, Rezai K, Lokiec F, Riveiro ME, Ouafik L. Berenguer-Daizé C, et al. Int J Cancer. 2016 Nov 1;139(9):2047-55. doi: 10.1002/ijc.30256. Epub 2016 Jul 30. Int J Cancer. 2016. PMID: 27388964
OTX015 (MK-8628), a novel BET inhibitor, exhibits antitumor activity in non-small cell and small cell lung cancer models harboring different oncogenic mutations.
Riveiro ME, Astorgues-Xerri L, Vazquez R, Frapolli R, Kwee I, Rinaldi A, Odore E, Rezai K, Bekradda M, Inghirami G, D'Incalci M, Noel K, Cvitkovic E, Raymond E, Bertoni F. Riveiro ME, et al. Oncotarget. 2016 Dec 20;7(51):84675-84687. doi: 10.18632/oncotarget.13181. Oncotarget. 2016. PMID: 27835869 Free PMC article.
Pharmacokinetics and antineoplastic activity of galectin-1-targeting OTX008 in combination with sunitinib.
Zucchetti M, Bonezzi K, Frapolli R, Sala F, Borsotti P, Zangarini M, Cvitkovic E, Noel K, Ubezio P, Giavazzi R, D'Incalci M, Taraboletti G. Zucchetti M, et al. Cancer Chemother Pharmacol. 2013 Oct;72(4):879-87. doi: 10.1007/s00280-013-2270-2. Epub 2013 Aug 24. Cancer Chemother Pharmacol. 2013. PMID: 23978989
Insights into the cellular pharmacological properties of the BET-inhibitor OTX015/MK-8628 (birabresib), alone and in combination, in leukemia models.
Astorgues-Xerri L, Vázquez R, Odore E, Rezai K, Kahatt C, Mackenzie S, Bekradda M, Coudé MM, Dombret H, Gardin C, Lokiec F, Raymond E, Noel K, Cvitkovic E, Herait P, Bertoni F, Riveiro ME. Astorgues-Xerri L, et al. Among authors: noel k. Leuk Lymphoma. 2019 Dec;60(12):3067-3070. doi: 10.1080/10428194.2019.1617860. Epub 2019 Jun 17. Leuk Lymphoma. 2019. PMID: 31204545 No abstract available.
International Survey on Determinants of Antibiotic Duration and Discontinuation in Pediatric Critically Ill Patients.
Noël KC, Papenburg J, Lacroix J, Quach C, O'Donnell S, Gonzales M, Willson DF, Gilfoyle E, McNally JD, Reynolds S, Kazzaz Y, Kawaguchi A, Sato M, Kongkiattikul L, Leteurtre S, Dubos F, Karaca Y, Chiusolo F, Piva J, Dendukuri N, Fontela PS; Canadian Critical Care Trials Group (CCCTG) and the Pediatric Lung Injury and Sepsis Investigators (PALISI) Network. Noël KC, et al. Pediatr Crit Care Med. 2020 Sep;21(9):e696-e706. doi: 10.1097/PCC.0000000000002397. Pediatr Crit Care Med. 2020. PMID: 32639469
Inclusive innovation in telehealth.
Noel K, Ellison B. Noel K, et al. NPJ Digit Med. 2020 Jun 25;3:89. doi: 10.1038/s41746-020-0296-5. eCollection 2020. NPJ Digit Med. 2020. PMID: 32613084 Free PMC article.
Heartland Virus in Humans and Ticks, Illinois, USA, 2018-2019.
Tuten HC, Burkhalter KL, Noel KR, Hernandez EJ, Yates S, Wojnowski K, Hartleb J, Debosik S, Holmes A, Stone CM. Tuten HC, et al. Among authors: noel kr. Emerg Infect Dis. 2020 Jul;26(7):1548-1552. doi: 10.3201/eid2607.200110. Emerg Infect Dis. 2020. PMID: 32568061 Free PMC article.
Deep Learning on Electronic Health Records to Improve Disease Coding Accuracy.
Rashidian S, Hajagos J, Moffitt RA, Wang F, Noel KM, Gupta RR, Tharakan MA, Saltz JH, Saltz MM. Rashidian S, et al. Among authors: noel km. AMIA Jt Summits Transl Sci Proc. 2019 May 6;2019:620-629. eCollection 2019. AMIA Jt Summits Transl Sci Proc. 2019. PMID: 31259017 Free PMC article.
The Clinical Utility of Respiratory Viral Testing in Hospitalized Children: A Meta-analysis.
Noël KC, Fontela PS, Winters N, Quach C, Gore G, Robinson J, Dendukuri N, Papenburg J. Noël KC, et al. Hosp Pediatr. 2019 Jul;9(7):483-494. doi: 10.1542/hpeds.2018-0233. Epub 2019 Jun 5. Hosp Pediatr. 2019. PMID: 31167816 Free article.
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