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Thresholds of Genotoxic and Non-Genotoxic Carcinogens.
Nohmi T. Nohmi T. Toxicol Res. 2018 Oct;34(4):281-290. doi: 10.5487/TR.2018.34.4.281. Epub 2018 Oct 15. Toxicol Res. 2018. PMID: 30370002 Free PMC article. Review.
Role of p53 in the progression from ochratoxin A-induced DNA damage to gene mutations in the kidneys of mice.
Kuroda K, Hibi D, Ishii Y, Yokoo Y, Takasu S, Kijima A, Matsushita K, Masumura K, Kodama Y, Yanai T, Sakai H, Nohmi T, Ogawa K, Umemura T. Kuroda K, et al. Among authors: Nohmi T. Toxicol Sci. 2015 Mar;144(1):65-76. doi: 10.1093/toxsci/kfu267. Epub 2015 Jan 29. Toxicol Sci. 2015. PMID: 25636497
Possible involvement of sulfotransferase 1A1 in estragole-induced DNA modification and carcinogenesis in the livers of female mice.
Suzuki Y, Umemura T, Ishii Y, Hibi D, Inoue T, Jin M, Sakai H, Kodama Y, Nohmi T, Yanai T, Nishikawa A, Ogawa K. Suzuki Y, et al. Among authors: Nohmi T. Mutat Res. 2012 Dec 12;749(1-2):23-8. doi: 10.1016/j.mrgentox.2012.07.002. Epub 2012 Aug 4. Mutat Res. 2012. PMID: 22885592
Combined ascorbic acid and sodium nitrite treatment induces oxidative DNA damage-associated mutagenicity in vitro, but lacks initiation activity in rat forestomach epithelium.
Kuroiwa Y, Yamada M, Matsui K, Okamura T, Ishii Y, Masumura K, Tasaki M, Umemura T, Mitsumori K, Nohmi T, Hirose M, Nishikawa A. Kuroiwa Y, et al. Among authors: Nohmi T. Toxicol Sci. 2008 Aug;104(2):274-82. doi: 10.1093/toxsci/kfn081. Epub 2008 Apr 22. Toxicol Sci. 2008. PMID: 18434339
Enhancing effects of carbon tetrachloride on in vivo mutagenicity in the liver of mice fed 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).
Okamura T, Ishii Y, Suzuki Y, Inoue T, Tasaki M, Kodama Y, Nohmi T, Mitsumori K, Umemura T, Nishikawa A. Okamura T, et al. Among authors: Nohmi T. J Toxicol Sci. 2010 Oct;35(5):709-20. doi: 10.2131/jts.35.709. J Toxicol Sci. 2010. PMID: 20930465
In the mutation spectra analysis of gpt mutant colonies, G:C to T:A transversions were predominantly observed regardless of CCl(4) injection, and clonal expansion of gpt colonies were increased in the co-treated group as compared with MeIQx alone group. ...
In the mutation spectra analysis of gpt mutant colonies, G:C to T:A transversions were predominantly observed regardless of CCl(4) in …
Impact of DNA polymerase ζ mutations on genotoxic thresholds of oxidative mutagens.
Suzuki T, Matsumoto K, Honma M, Nohmi T. Suzuki T, et al. Among authors: Nohmi T. Mutat Res Genet Toxicol Environ Mutagen. 2018 Apr;828:10-14. doi: 10.1016/j.mrgentox.2018.02.001. Epub 2018 Feb 7. Mutat Res Genet Toxicol Environ Mutagen. 2018. PMID: 29555059
Oxidative DNA damage and in vivo mutagenicity caused by reactive oxygen species generated in the livers of p53-proficient or -deficient gpt delta mice treated with non-genotoxic hepatocarcinogens.
Tasaki M, Kuroiwa Y, Inoue T, Hibi D, Matsushita K, Ishii Y, Maruyama S, Nohmi T, Nishikawa A, Umemura T. Tasaki M, et al. Among authors: Nohmi T. J Appl Toxicol. 2013 Dec;33(12):1433-41. doi: 10.1002/jat.2807. Epub 2012 Sep 12. J Appl Toxicol. 2013. PMID: 22972318
Oxidative DNA damage and reporter gene mutation in the livers of gpt delta rats given non-genotoxic hepatocarcinogens with cytochrome P450-inducible potency.
Tasaki M, Umemura T, Suzuki Y, Hibi D, Inoue T, Okamura T, Ishii Y, Maruyama S, Nohmi T, Nishikawa A. Tasaki M, et al. Among authors: Nohmi T. Cancer Sci. 2010 Dec;101(12):2525-30. doi: 10.1111/j.1349-7006.2010.01705.x. Cancer Sci. 2010. PMID: 20735435
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