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423 results
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The tumor suppressor Lats2 is pivotal in Aurora A and Aurora B signaling during mitosis.
Yabuta N, Mukai S, Okada N, Aylon Y, Nojima H. Yabuta N, et al. Among authors: nojima h. Cell Cycle. 2011 Aug 15;10(16):2724-36. doi: 10.4161/cc.10.16.16873. Epub 2011 Aug 15. Cell Cycle. 2011. PMID: 21822051
Silencing of the Lats2 tumor suppressor overrides a p53-dependent oncogenic stress checkpoint and enables mutant H-Ras-driven cell transformation.
Aylon Y, Yabuta N, Besserglick H, Buganim Y, Rotter V, Nojima H, Oren M. Aylon Y, et al. Among authors: nojima h. Oncogene. 2009 Dec 17;28(50):4469-79. doi: 10.1038/onc.2009.270. Epub 2009 Oct 26. Oncogene. 2009. PMID: 19855428 Free PMC article.
ELAS1-mediated inhibition of the cyclin G1-B'γ interaction promotes cancer cell apoptosis via stabilization and activation of p53.
Ohno S, Naito Y, Mukai S, Yabuta N, Nojima H. Ohno S, et al. Among authors: nojima h. Oncogene. 2015 Dec 3;34(49):5983-96. doi: 10.1038/onc.2015.47. Epub 2015 Apr 27. Oncogene. 2015. PMID: 25915850
Comprehensive phenotypic analysis of knockout mice deficient in cyclin G1 and cyclin G2.
Ohno S, Ikeda JI, Naito Y, Okuzaki D, Sasakura T, Fukushima K, Nishikawa Y, Ota K, Kato Y, Wang M, Torigata K, Kasama T, Uchihashi T, Miura D, Yabuta N, Morii E, Nojima H. Ohno S, et al. Among authors: nojima h. Sci Rep. 2016 Dec 16;6:39091. doi: 10.1038/srep39091. Sci Rep. 2016. PMID: 27982046 Free PMC article.
Gefitinib and luteolin cause growth arrest of human prostate cancer PC-3 cells via inhibition of cyclin G-associated kinase and induction of miR-630.
Sakurai MA, Ozaki Y, Okuzaki D, Naito Y, Sasakura T, Okamoto A, Tabara H, Inoue T, Hagiyama M, Ito A, Yabuta N, Nojima H. Sakurai MA, et al. Among authors: nojima h. PLoS One. 2014 Jun 27;9(6):e100124. doi: 10.1371/journal.pone.0100124. eCollection 2014. PLoS One. 2014. PMID: 24971999 Free PMC article.
N-terminal truncation of Lats1 causes abnormal cell growth control and chromosomal instability.
Yabuta N, Mukai S, Okamoto A, Okuzaki D, Suzuki H, Torigata K, Yoshida K, Okada N, Miura D, Ito A, Ikawa M, Okabe M, Nojima H. Yabuta N, et al. Among authors: nojima h. J Cell Sci. 2013 Jan 15;126(Pt 2):508-20. doi: 10.1242/jcs.113431. Epub 2012 Dec 10. J Cell Sci. 2013. PMID: 23230145
LATS1/2 kinases trigger self-renewal of cancer stem cells in aggressive oral cancer.
Nozaki M, Yabuta N, Fukuzawa M, Mukai S, Okamoto A, Sasakura T, Fukushima K, Naito Y, Longmore GD, Nojima H. Nozaki M, et al. Among authors: nojima h. Oncotarget. 2019 Feb 1;10(10):1014-1030. doi: 10.18632/oncotarget.26583. eCollection 2019 Feb 1. Oncotarget. 2019. PMID: 30800215 Free PMC article.
GAK is phosphorylated by c-Src and translocated from the centrosome to chromatin at the end of telophase.
Fukushima K, Wang M, Naito Y, Uchihashi T, Kato Y, Mukai S, Yabuta N, Nojima H. Fukushima K, et al. Among authors: nojima h. Cell Cycle. 2017 Mar 4;16(5):415-427. doi: 10.1080/15384101.2016.1241916. Epub 2017 Jan 31. Cell Cycle. 2017. PMID: 28135906 Free PMC article.
Clathrin heavy chain phosphorylated at T606 plays a role in proper cell division.
Yabuno Y, Uchihashi T, Sasakura T, Shimizu H, Naito Y, Fukushima K, Ota K, Kogo M, Nojima H, Yabuta N. Yabuno Y, et al. Among authors: nojima h. Cell Cycle. 2019 Aug;18(16):1976-1994. doi: 10.1080/15384101.2019.1637201. Epub 2019 Jul 4. Cell Cycle. 2019. PMID: 31272276 Free PMC article.
Cyclin G-associated kinase regulates protein phosphatase 2A by phosphorylation of its B'γ subunit.
Naito Y, Shimizu H, Kasama T, Sato J, Tabara H, Okamoto A, Yabuta N, Nojima H. Naito Y, et al. Among authors: nojima h. Cell Cycle. 2012 Feb 1;11(3):604-16. doi: 10.4161/cc.11.3.19114. Epub 2012 Feb 1. Cell Cycle. 2012. PMID: 22262175
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