Nolte RT - Search Results

1

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma.

Nolte RT, Wisely GB, Westin S, Cobb JE, Lambert MH, Kurokawa R, Rosenfeld MG, Willson TM, Glass CK, Milburn MV. Nolte RT, et al. Nature. 1998 Sep 10;395(6698):137-43. doi: 10.1038/25931. Nature. 1998. PMID: 9744270

2

Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha.

Xu HE, Stanley TB, Montana VG, Lambert MH, Shearer BG, Cobb JE, McKee DD, Galardi CM, Plunket KD, Nolte RT, Parks DJ, Moore JT, Kliewer SA, Willson TM, Stimmel JB. Xu HE, et al. Among authors: nolte rt. Nature. 2002 Feb 14;415(6873):813-7. doi: 10.1038/415813a. Nature. 2002. PMID: 11845213

3

Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators.

Westin S, Kurokawa R, Nolte RT, Wisely GB, McInerney EM, Rose DW, Milburn MV, Rosenfeld MG, Glass CK. Westin S, et al. Among authors: nolte rt. Nature. 1998 Sep 10;395(6698):199-202. doi: 10.1038/26040. Nature. 1998. PMID: 9744281

4

X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.

Wang L, Zuercher WJ, Consler TG, Lambert MH, Miller AB, Orband-Miller LA, McKee DD, Willson TM, Nolte RT. Wang L, et al. Among authors: nolte rt. J Biol Chem. 2006 Dec 8;281(49):37773-81. doi: 10.1074/jbc.M608410200. Epub 2006 Sep 21. J Biol Chem. 2006. PMID: 16990259 Free article.

5

Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation.

McInerney EM, Rose DW, Flynn SE, Westin S, Mullen TM, Krones A, Inostroza J, Torchia J, Nolte RT, Assa-Munt N, Milburn MV, Glass CK, Rosenfeld MG. McInerney EM, et al. Among authors: nolte rt. Genes Dev. 1998 Nov 1;12(21):3357-68. doi: 10.1101/gad.12.21.3357. Genes Dev. 1998. PMID: 9808623 Free PMC article.

6

Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity.

Xu RX, Hassell AM, Vanderwall D, Lambert MH, Holmes WD, Luther MA, Rocque WJ, Milburn MV, Zhao Y, Ke H, Nolte RT. Xu RX, et al. Among authors: nolte rt. Science. 2000 Jun 9;288(5472):1822-5. doi: 10.1126/science.288.5472.1822. Science. 2000. PMID: 10846163

7

Crystallization of protein-ligand complexes.

Hassell AM, An G, Bledsoe RK, Bynum JM, Carter HL 3rd, Deng SJ, Gampe RT, Grisard TE, Madauss KP, Nolte RT, Rocque WJ, Wang L, Weaver KL, Williams SP, Wisely GB, Xu R, Shewchuk LM. Hassell AM, et al. Among authors: nolte rt. Acta Crystallogr D Biol Crystallogr. 2007 Jan;63(Pt 1):72-9. doi: 10.1107/S0907444906047020. Epub 2006 Dec 13. Acta Crystallogr D Biol Crystallogr. 2007. PMID: 17164529 Free PMC article. Review.

8

Structure-guided synthesis of tamoxifen analogs with improved selectivity for the orphan ERRgamma.

Chao EY, Collins JL, Gaillard S, Miller AB, Wang L, Orband-Miller LA, Nolte RT, McDonnell DP, Willson TM, Zuercher WJ. Chao EY, et al. Among authors: nolte rt. Bioorg Med Chem Lett. 2006 Feb 15;16(4):821-4. doi: 10.1016/j.bmcl.2005.11.030. Epub 2005 Nov 22. Bioorg Med Chem Lett. 2006. PMID: 16307879

9

Crystal structures of the catalytic domain of phosphodiesterase 4B complexed with AMP, 8-Br-AMP, and rolipram.

Xu RX, Rocque WJ, Lambert MH, Vanderwall DE, Luther MA, Nolte RT. Xu RX, et al. Among authors: nolte rt. J Mol Biol. 2004 Mar 19;337(2):355-65. doi: 10.1016/j.jmb.2004.01.040. J Mol Biol. 2004. PMID: 15003452

10

Co-crystal structure guided array synthesis of PPARgamma inverse agonists.

Trump RP, Cobb JE, Shearer BG, Lambert MH, Nolte RT, Willson TM, Buckholz RG, Zhao SM, Leesnitzer LM, Iannone MA, Pearce KH, Billin AN, Hoekstra WJ. Trump RP, et al. Among authors: nolte rt. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3916-20. doi: 10.1016/j.bmcl.2007.04.111. Epub 2007 May 18. Bioorg Med Chem Lett. 2007. PMID: 17533125

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