Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
1998 1
2000 3
2001 2
2005 2
2006 2
2007 4
2008 2
2010 6
2011 1
2012 1
2013 1
2014 2
2015 3
2016 2
2017 3
2018 2
2019 1
2020 2
2021 2
2022 1
2023 1

Text availability

Article attribute

Article type

Publication date

Search Results

38 results

Results by year

Citations

1 article found by citation matching

Search results

Filters applied: . Clear all
Page 1
Nonsteroidal anti-inflammatory drugs are associated with increased neuritic plaques.
Sonnen JA, Larson EB, Walker RL, Haneuse S, Crane PK, Gray SL, Breitner JC, Montine TJ. Sonnen JA, et al. Neurology. 2010 Sep 28;75(13):1203-10. doi: 10.1212/WNL.0b013e3181f52db1. Epub 2010 Sep 1. Neurology. 2010. PMID: 20811000 Free PMC article.
OBJECTIVES: Observational and experimental studies suggest that nonsteroidal anti-inflammatory drugs (NSAIDs) may protect against Alzheimer disease (AD); however, clinical trials and other observational studies, including the Adult Changes in Thought ( …
OBJECTIVES: Observational and experimental studies suggest that nonsteroidal anti-inflammatory drugs (NSAIDs) ma …
Alzheimer's disease and inflammation: a review of cellular and therapeutic mechanisms.
Halliday G, Robinson SR, Shepherd C, Kril J. Halliday G, et al. Clin Exp Pharmacol Physiol. 2000 Jan-Feb;27(1-2):1-8. doi: 10.1046/j.1440-1681.2000.03200.x. Clin Exp Pharmacol Physiol. 2000. PMID: 10696521 Review.
There is a considerable body of in vitro evidence indicating that the inflammatory response of microglial cells is reduced by non-steroidal anti-inflammatory drugs (NSAID). ...Cyclo-oxygenase 2 enzyme is constitutively expressed in neuron …
There is a considerable body of in vitro evidence indicating that the inflammatory response of microglial cells is reduced by non …
Immunological aspects of alzheimer's disease: therapeutic implications.
Hoozemans JJ, Rozemuller AJ, Veerhuis R, Eikelenboom P. Hoozemans JJ, et al. BioDrugs. 2001;15(5):325-37. doi: 10.2165/00063030-200115050-00004. BioDrugs. 2001. PMID: 11437695 Review.
Several lines of evidence indicate that an inflammatory process contributes to the pathology of AD. First, inflammatory proteins have been identified as being associated with neuritic plaques and in glial cells surrounding these plaques. …
Several lines of evidence indicate that an inflammatory process contributes to the pathology of AD. First, inflammatory protei …
Interactions between APP secretases and inflammatory mediators.
Sastre M, Walter J, Gentleman SM. Sastre M, et al. J Neuroinflammation. 2008 Jun 18;5:25. doi: 10.1186/1742-2094-5-25. J Neuroinflammation. 2008. PMID: 18564425 Free PMC article. Review.
There is now a large body of evidence linking inflammation to Alzheimer's disease (AD). This association manifests itself neuropathologically in the presence of activated microglia and astrocytes around neuritic plaques and increased levels of infla …
There is now a large body of evidence linking inflammation to Alzheimer's disease (AD). This association manifests itself neuropathol …
Alzheimer's disease: etiologies, pathophysiology, cognitive reserve, and treatment opportunities.
Cummings JL, Vinters HV, Cole GM, Khachaturian ZS. Cummings JL, et al. Neurology. 1998 Jul;51(1 Suppl 1):S2-17; discussion S65-7. doi: 10.1212/wnl.51.1_suppl_1.s2. Neurology. 1998. PMID: 9674758 Review.
All mutations known to cause AD increase the production of beta-amyloid peptide. This protein is derived from amyloid precursor protein and, when aggregated in a beta-pleated sheet configuration, is neurotoxic and forms the core of neuritic plaques …
All mutations known to cause AD increase the production of beta-amyloid peptide. This protein is derived from amyloid p …
Clinical aspects of inflammation in Alzheimer's disease.
Rosenberg PB. Rosenberg PB. Int Rev Psychiatry. 2005 Dec;17(6):503-14. doi: 10.1080/02646830500382037. Int Rev Psychiatry. 2005. PMID: 16401549 Review.
New anti-inflammatory agents for treating or preventing AD may include novel NSAIDs and opioid antagonists. These developments provide an alternative or potential adjunct to anti-amyloid therapies for AD....
New anti-inflammatory agents for treating or preventing AD may include novel NSAIDs and opioid antagonists. These devel …
Amyloid-beta vaccination, but not nitro-nonsteroidal anti-inflammatory drug treatment, increases vascular amyloid and microhemorrhage while both reduce parenchymal amyloid.
Wilcock DM, Jantzen PT, Li Q, Morgan D, Gordon MN. Wilcock DM, et al. Neuroscience. 2007 Feb 9;144(3):950-60. doi: 10.1016/j.neuroscience.2006.10.020. Epub 2006 Nov 28. Neuroscience. 2007. PMID: 17137722 Free PMC article.
We found that all treatments reduced amyloid deposition, both compact and diffuse, to the same extent while only vaccinated animals, with or without nonsteroidal anti-inflammatory drug (NSAID) treatment, showed increased microglial activation …
We found that all treatments reduced amyloid deposition, both compact and diffuse, to the same extent while only vaccinated animals, …
Altered expression of COX-2 in subdivisions of the hippocampus during aging and in Alzheimer's disease: the Hisayama Study.
Fujimi K, Noda K, Sasaki K, Wakisaka Y, Tanizaki Y, Iida M, Kiyohara Y, Kanba S, Iwaki T. Fujimi K, et al. Dement Geriatr Cogn Disord. 2007;23(6):423-31. doi: 10.1159/000101957. Epub 2007 Apr 23. Dement Geriatr Cogn Disord. 2007. PMID: 17457030
BACKGROUND: It has been reported that nonsteroidal anti-inflammatory drugs may delay the onset of Alzheimer's disease (AD). Since nonsteroidal anti-inflammatory drugs inhibit cyclooxygenase (COX), COX-2, an inducible form of …
BACKGROUND: It has been reported that nonsteroidal anti-inflammatory drugs may delay the onset of Alzheimer's di …
Indomethacin Disrupts the Formation of β-Amyloid Plaques via an α2-Macroglobulin-Activating lrp1-Dependent Mechanism.
Guan PP, Yang LQ, Xu GB, Wang P. Guan PP, et al. Int J Mol Sci. 2021 Jul 30;22(15):8185. doi: 10.3390/ijms22158185. Int J Mol Sci. 2021. PMID: 34360951 Free PMC article.
Epidemiological studies have implied that the nonsteroidal anti-inflammatory drug (NSAID) indomethacin slows the development and progression of Alzheimer's disease (AD). ...By screening AD-associated genes, we observed that a marked increase in …
Epidemiological studies have implied that the nonsteroidal anti-inflammatory drug (NSAID) indomethacin slows the develo …
Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial.
Small GW, Siddarth P, Li Z, Miller KJ, Ercoli L, Emerson ND, Martinez J, Wong KP, Liu J, Merrill DA, Chen ST, Henning SM, Satyamurthy N, Huang SC, Heber D, Barrio JR. Small GW, et al. Am J Geriatr Psychiatry. 2018 Mar;26(3):266-277. doi: 10.1016/j.jagp.2017.10.010. Epub 2017 Oct 27. Am J Geriatr Psychiatry. 2018. PMID: 29246725 Free article. Clinical Trial.
OBJECTIVE: Because curcumin's anti-inflammatory properties may protect the brain from neurodegeneration, we studied its effect on memory in non-demented adults and explored its impact on brain amyloid and tau accumulation using 2-(1-{6-[(2-[F-18]fluoro …
OBJECTIVE: Because curcumin's anti-inflammatory properties may protect the brain from neurodegeneration, we studied its effect …
38 results