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Pharmacological HIF2α inhibition improves VHL disease-associated phenotypes in zebrafish model.
J Clin Invest. 2015 May;125(5):1987-97. doi: 10.1172/JCI73665. Epub 2015 Apr 13.
J Clin Invest. 2015.
PMID: 25866969
Free PMC article.
HIF2a inhibitors for the treatment of VHL disease.
Metelo AM, Noonan H, Iliopoulos O.
Metelo AM, et al.
Oncotarget. 2015 Sep 15;6(27):23036-7. doi: 10.18632/oncotarget.4564.
Oncotarget. 2015.
PMID: 26325097
Free PMC article.
Review.
No abstract available.
Item in Clipboard
Loss of vhl in the zebrafish pronephros recapitulates early stages of human clear cell renal cell carcinoma.
Noonan HR, Metelo AM, Kamei CN, Peterson RT, Drummond IA, Iliopoulos O.
Noonan HR, et al.
Dis Model Mech. 2016 Aug 1;9(8):873-84. doi: 10.1242/dmm.024380.
Dis Model Mech. 2016.
PMID: 27491085
Free PMC article.
Item in Clipboard
NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism.
Allouche J, Rachmin I, Adhikari K, Pardo LM, Lee JH, McConnell AM, Kato S, Fan S, Kawakami A, Suita Y, Wakamatsu K, Igras V, Zhang J, Navarro PP, Lugo CM, Noonan HR, Christie KA, Itin K, Mujahid N, Lo JA, Won CH, Evans CL, Weng QY, Wang H, Osseiran S, Lovas A, Németh I, Cozzio A, Navarini AA, Hsiao JJ, Nguyen N, Kemény LV, Iliopoulos O, Berking C, Ruzicka T, Gonzalez-José R, Bortolini MC, Canizales-Quinteros S, Acuna-Alonso V, Gallo C, Poletti G, Bedoya G, Rothhammer F, Ito S, Schiaffino MV, Chao LH, Kleinstiver BP, Tishkoff S, Zon LI, Nijsten T, Ruiz-Linares A, Fisher DE, Roider E.
Allouche J, et al. Among authors: noonan hr.
Cell. 2021 Aug 5;184(16):4268-4283.e20. doi: 10.1016/j.cell.2021.06.022. Epub 2021 Jul 6.
Cell. 2021.
PMID: 34233163
Free PMC article.
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Clcn7F318L/+ as a new mouse model of Albers-Schönberg disease.
Caetano-Lopes J, Lessard SG, Hann S, Espinoza K, Kang KS, Lim KE, Horan DJ, Noonan HR, Hu D, Baron R, Robling AG, Warman ML.
Caetano-Lopes J, et al. Among authors: noonan hr.
Bone. 2017 Dec;105:253-261. doi: 10.1016/j.bone.2017.09.007. Epub 2017 Sep 20.
Bone. 2017.
PMID: 28942122
Free PMC article.
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