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Growth associated proteins in tumor cells and stroma related to disease progression of colon cancer accounting for tumor tissue PGE2 content.
Cahlin C, Lönnroth C, Arvidsson A, Nordgren S, Lundholm K. Cahlin C, et al. Among authors: nordgren s. Int J Oncol. 2008 Apr;32(4):909-18. Int J Oncol. 2008. PMID: 18360718
A pharmacological analysis of the cholinergic regulation of urokinase-type plasminogen activator secretion in the human colon cancer cell line, HT-29.
Novotny A, Edsparr K, Nylund G, Khorram-Manesh A, Albertsson P, Nordgren S, Delbro DS. Novotny A, et al. Among authors: nordgren s. Eur J Pharmacol. 2010 Nov 10;646(1-3):22-30. doi: 10.1016/j.ejphar.2010.08.004. Epub 2010 Aug 19. Eur J Pharmacol. 2010. PMID: 20727878
Downregulation of Prominin 1/CD133 expression in colorectal cancer by NSAIDs following short-term preoperative treatment.
Lönnroth C, Andersson M, Nordgren S, Lundholm K. Lönnroth C, et al. Among authors: nordgren s. Int J Oncol. 2012 Jul;41(1):15-23. doi: 10.3892/ijo.2012.1460. Epub 2012 May 2. Int J Oncol. 2012. PMID: 22552364
Is acetylcholine a signaling molecule for human colon cancer progression?
Novotny A, Ryberg K, Heiman Ullmark J, Nilsson L, Khorram-Manesh A, Nordgren S, Delbro DS, Nylund G. Novotny A, et al. Among authors: nordgren s. Scand J Gastroenterol. 2011 Apr;46(4):446-55. doi: 10.3109/00365521.2010.539252. Epub 2011 Jan 26. Scand J Gastroenterol. 2011. PMID: 21265716
Genes with relevance for early to late progression of colon carcinoma based on combined genomic and transcriptomic information from the same patients.
Lagerstedt KK, Kristiansson E, Lönnroth C, Andersson M, Iresjö BM, Gustafsson A, Hansson E, Kressner U, Nordgren S, Enlund F, Lundholm K. Lagerstedt KK, et al. Among authors: nordgren s. Cancer Inform. 2010 Apr 23;9:79-91. doi: 10.4137/cin.s4545. Cancer Inform. 2010. PMID: 20467480 Free PMC article.
Receptor and enzyme expression for prostanoid metabolism in colorectal cancer related to tumor tissue PGE2.
Gustafsson A, Andersson M, Lagerstedt K, Lönnroth C, Nordgren S, Lundholm K. Gustafsson A, et al. Among authors: nordgren s. Int J Oncol. 2010 Feb;36(2):469-78. Int J Oncol. 2010. PMID: 20043083 Clinical Trial.
Differential prognostic impact of uPA and PAI-1 in colon and rectal cancer.
Langenskiöld M, Holmdahl L, Angenete E, Falk P, Nordgren S, Ivarsson ML. Langenskiöld M, et al. Among authors: nordgren s. Tumour Biol. 2009;30(4):210-20. doi: 10.1159/000239796. Epub 2009 Sep 21. Tumour Biol. 2009. PMID: 19776673
Tumor genome wide DNA alterations assessed by array CGH in patients with poor and excellent survival following operation for colorectal cancer.
Lagerstedt KK, Staaf J, Jönsson G, Hansson E, Lönnroth C, Kressner U, Lindström L, Nordgren S, Borg A, Lundholm K. Lagerstedt KK, et al. Among authors: nordgren s. Cancer Inform. 2007 Oct 12;3:341-55. Cancer Inform. 2007. PMID: 19455253 Free PMC article.
Preoperative treatment with a non-steroidal anti-inflammatory drug (NSAID) increases tumor tissue infiltration of seemingly activated immune cells in colorectal cancer.
Lönnroth C, Andersson M, Arvidsson A, Nordgren S, Brevinge H, Lagerstedt K, Lundholm K. Lönnroth C, et al. Among authors: nordgren s. Cancer Immun. 2008 Feb 29;8:5. Cancer Immun. 2008. PMID: 18307280 Free PMC article. Clinical Trial.
Prostanoid receptor expression in colorectal cancer related to tumor stage, differentiation and progression.
Gustafsson A, Hansson E, Kressner U, Nordgren S, Andersson M, Lönnroth C, Lundholm K. Gustafsson A, et al. Among authors: nordgren s. Acta Oncol. 2007;46(8):1107-12. doi: 10.1080/02841860701403061. Acta Oncol. 2007. PMID: 17943472
Therefore, future studies should be performed on defined cells within the tumor tissue compartment determining whether any prostanoid receptor(s) is useful as a molecular target in treatment or prevention of colorectal cancer....
Therefore, future studies should be performed on defined cells within the tumor tissue compartment determining whether any prostanoid recept …
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