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Some cannabinoid receptor ligands and their distomers are direct-acting openers of SUR1 K(ATP) channels.
Lynch CJ, Zhou Q, Shyng SL, Heal DJ, Cheetham SC, Dickinson K, Gregory P, Firnges M, Nordheim U, Goshorn S, Reiche D, Turski L, Antel J. Lynch CJ, et al. Among authors: nordheim u. Am J Physiol Endocrinol Metab. 2012 Mar 1;302(5):E540-51. doi: 10.1152/ajpendo.00250.2011. Epub 2011 Dec 13. Am J Physiol Endocrinol Metab. 2012. PMID: 22167524 Free PMC article.