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Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis.
Gallo EM, Loch DC, Habashi JP, Calderon JF, Chen Y, Bedja D, van Erp C, Gerber EE, Parker SJ, Sauls K, Judge DP, Cooke SK, Lindsay ME, Rouf R, Myers L, ap Rhys CM, Kent KC, Norris RA, Huso DL, Dietz HC. Gallo EM, et al. Among authors: norris ra. J Clin Invest. 2014 Jan;124(1):448-60. doi: 10.1172/JCI69666. Epub 2013 Dec 20. J Clin Invest. 2014. PMID: 24355923 Free PMC article.
Mutations in the TGF-β repressor SKI cause Shprintzen-Goldberg syndrome with aortic aneurysm.
Doyle AJ, Doyle JJ, Bessling SL, Maragh S, Lindsay ME, Schepers D, Gillis E, Mortier G, Homfray T, Sauls K, Norris RA, Huso ND, Leahy D, Mohr DW, Caulfield MJ, Scott AF, Destrée A, Hennekam RC, Arn PH, Curry CJ, Van Laer L, McCallion AS, Loeys BL, Dietz HC. Doyle AJ, et al. Among authors: norris ra. Nat Genet. 2012 Nov;44(11):1249-54. doi: 10.1038/ng.2421. Epub 2012 Sep 30. Nat Genet. 2012. PMID: 23023332 Free PMC article.
Inheritance Impacts Mitral Valve Insufficiency.
Judge DP, Norris RA. Judge DP, et al. Among authors: norris ra. Circ Cardiovasc Genet. 2017 Oct;10(5):e001920. doi: 10.1161/CIRCGENETICS.117.001920. Circ Cardiovasc Genet. 2017. PMID: 28993408 No abstract available.
Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β.
Teekakirikul P, Eminaga S, Toka O, Alcalai R, Wang L, Wakimoto H, Nayor M, Konno T, Gorham JM, Wolf CM, Kim JB, Schmitt JP, Molkentin JD, Norris RA, Tager AM, Hoffman SR, Markwald RR, Seidman CE, Seidman JG. Teekakirikul P, et al. Among authors: norris ra. J Clin Invest. 2010 Oct;120(10):3520-9. doi: 10.1172/JCI42028. Epub 2010 Sep 1. J Clin Invest. 2010. PMID: 20811150 Free PMC article.
Increased Infiltration of Extra-Cardiac Cells in Myxomatous Valve Disease.
Sauls K, Toomer K, Williams K, Johnson AJ, Markwald RR, Hajdu Z, Norris RA. Sauls K, et al. Among authors: norris ra. J Cardiovasc Dev Dis. 2015 Sep;2(3):200-213. doi: 10.3390/jcdd2030200. Epub 2015 Jul 24. J Cardiovasc Dev Dis. 2015. PMID: 26473162 Free PMC article.
Embryonic Development of the Bicuspid Aortic Valve.
Martin PS, Kloesel B, Norris RA, Lindsay M, Milan D, Body SC. Martin PS, et al. Among authors: norris ra. J Cardiovasc Dev Dis. 2015 Dec;2(4):248-272. doi: 10.3390/jcdd2040248. Epub 2015 Oct 2. J Cardiovasc Dev Dis. 2015. PMID: 28529942 Free PMC article.
106 results