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Record high Pacific Arctic seawater temperatures and delayed sea ice advance in response to episodic atmospheric blocking.
Kodaira T, Waseda T, Nose T, Inoue J. Kodaira T, et al. Among authors: nose t. Sci Rep. 2020 Nov 27;10(1):20830. doi: 10.1038/s41598-020-77488-y. Sci Rep. 2020. PMID: 33247199 Free PMC article.
Maternal human habituation enhances sons' risk of human-caused mortality in a large carnivore, brown bears.
Shimozuru M, Shirane Y, Yamanaka M, Nakanishi M, Ishinazaka T, Kasai S, Nose T, Shirayanagi M, Jimbo M, Tsuruga H, Mano T, Tsubota T. Shimozuru M, et al. Among authors: nose t. Sci Rep. 2020 Oct 5;10(1):16498. doi: 10.1038/s41598-020-73057-5. Sci Rep. 2020. PMID: 33020503 Free PMC article.
Mechanistic Insights into a DMSO-Perturbing Inhibitory Assay of Hyaluronidase.
Tomohara K, Ohashi N, Nose T. Tomohara K, et al. Among authors: nose t. Biochemistry. 2020 Oct 13;59(40):3879-3888. doi: 10.1021/acs.biochem.0c00594. Epub 2020 Sep 25. Biochemistry. 2020. PMID: 32940996
12α-Hydroxylated bile acid induces hepatic steatosis with dysbiosis in rats.
Lee JY, Shimizu H, Hagio M, Fukiya S, Watanabe M, Tanaka Y, Joe GH, Iwaya H, Yoshitsugu R, Kikuchi K, Tsuji M, Baba N, Nose T, Tada K, Hanai T, Hori S, Takeuchi A, Furukawa Y, Shirouchi B, Sato M, Ooka T, Ogura Y, Hayashi T, Yokota A, Ishizuka S. Lee JY, et al. Among authors: nose t. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Dec;1865(12):158811. doi: 10.1016/j.bbalip.2020.158811. Epub 2020 Sep 5. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32896622 Free article.
Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation.
Okumura K, Akao M, Yoshida T, Kawata M, Okazaki O, Akashi S, Eshima K, Tanizawa K, Fukuzawa M, Hayashi T, Akishita M, Lip GYH, Yamashita T; ELDERCARE-AF Committees and Investigators. Okumura K, et al. N Engl J Med. 2020 Oct 29;383(18):1735-1745. doi: 10.1056/NEJMoa2012883. Epub 2020 Aug 30. N Engl J Med. 2020. PMID: 32865374 Clinical Trial.
Evaluation of the Influence of Halogenation on the Binding of Bisphenol A to the Estrogen-Related Receptor γ.
Suyama K, Kaneko S, Kesamaru H, Liu X, Matsushima A, Kakuta Y, Okubo T, Kasatani K, Nose T. Suyama K, et al. Among authors: nose t. Chem Res Toxicol. 2020 Apr 20;33(4):889-902. doi: 10.1021/acs.chemrestox.9b00379. Epub 2020 Mar 11. Chem Res Toxicol. 2020. PMID: 32105061
Bisphenol AF: Halogen bonding effect is a major driving force for the dual ERα-agonist and ERβ-antagonist activities.
Liu X, Suyama K, Shiki J, Torikai K, Nose T, Shimohigashi M, Shimohigashi Y. Liu X, et al. Among authors: nose t. Bioorg Med Chem. 2020 Feb 1;28(3):115274. doi: 10.1016/j.bmc.2019.115274. Epub 2019 Dec 18. Bioorg Med Chem. 2020. PMID: 31879182
Early identification of promiscuous attributes of aldose reductase inhibitors using a DMSO-perturbation assay.
Tomohara K, Hasegawa N, Adachi I, Horino Y, Nose T. Tomohara K, et al. Among authors: nose t. Bioorg Med Chem Lett. 2020 Jan 15;30(2):126815. doi: 10.1016/j.bmcl.2019.126815. Epub 2019 Nov 9. Bioorg Med Chem Lett. 2020. PMID: 31744675
DMSO-Perturbing Assay for Identifying Promiscuous Enzyme Inhibitors.
Tomohara K, Adachi I, Horino Y, Kesamaru H, Abe H, Suyama K, Nose T. Tomohara K, et al. Among authors: nose t. ACS Med Chem Lett. 2019 May 10;10(6):923-928. doi: 10.1021/acsmedchemlett.9b00093. eCollection 2019 Jun 13. ACS Med Chem Lett. 2019. PMID: 31223449 Free PMC article.
Receptor-binding affinities of bisphenol A and its next-generation analogs for human nuclear receptors.
Liu X, Sakai H, Nishigori M, Suyama K, Nawaji T, Ikeda S, Nishigouchi M, Okada H, Matsushima A, Nose T, Shimohigashi M, Shimohigashi Y. Liu X, et al. Among authors: nose t. Toxicol Appl Pharmacol. 2019 Aug 15;377:114610. doi: 10.1016/j.taap.2019.114610. Epub 2019 Jun 10. Toxicol Appl Pharmacol. 2019. PMID: 31195007
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