Novak P - Search Results

1

First-in-man tau vaccine targeting structural determinants essential for pathological tau-tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheimer's disease model.

Kontsekova E, Zilka N, Kovacech B, Novak P, Novak M. Kontsekova E, et al. Among authors: novak p, novak m. Alzheimers Res Ther. 2014 Aug 1;6(4):44. doi: 10.1186/alzrt278. eCollection 2014. Alzheimers Res Ther. 2014. PMID: 25478017 Free PMC article.

2

Genetic background modifies neurodegeneration and neuroinflammation driven by misfolded human tau protein in rat model of tauopathy: implication for immunomodulatory approach to Alzheimer's disease.

Stozicka Z, Zilka N, Novak P, Kovacech B, Bugos O, Novak M. Stozicka Z, et al. Among authors: novak p, novak m. J Neuroinflammation. 2010 Oct 12;7:64. doi: 10.1186/1742-2094-7-64. J Neuroinflammation. 2010. PMID: 20937161 Free PMC article.

3

First transgenic rat model developing progressive cortical neurofibrillary tangles.

Filipcik P, Zilka N, Bugos O, Kucerak J, Koson P, Novak P, Novak M. Filipcik P, et al. Among authors: novak p, novak m. Neurobiol Aging. 2012 Jul;33(7):1448-56. doi: 10.1016/j.neurobiolaging.2010.10.015. Epub 2010 Dec 31. Neurobiol Aging. 2012. PMID: 21196063

4

Tauons and prions: infamous cousins?

Novak P, Prcina M, Kontsekova E. Novak P, et al. J Alzheimers Dis. 2011;26(3):413-30. doi: 10.3233/JAD-2011-110194. J Alzheimers Dis. 2011. PMID: 21694453 Review.

5

Tau protein phosphorylation in diverse brain areas of normal and CRH deficient mice: up-regulation by stress.

Filipcik P, Novak P, Mravec B, Ondicova K, Krajciova G, Novak M, Kvetnansky R. Filipcik P, et al. Among authors: novak p, novak m. Cell Mol Neurobiol. 2012 Jul;32(5):837-45. doi: 10.1007/s10571-011-9788-9. Epub 2012 Jan 6. Cell Mol Neurobiol. 2012. PMID: 22222439

6

Tauopathy in transgenic (SHR72) rats impairs function of central noradrenergic system and promotes neuroinflammation.

Mravec B, Lejavova K, Vargovic P, Ondicova K, Horvathova L, Novak P, Manz G, Filipcik P, Novak M, Kvetnansky R. Mravec B, et al. Among authors: novak p, novak m. J Neuroinflammation. 2016 Jan 20;13:15. doi: 10.1186/s12974-016-0482-1. J Neuroinflammation. 2016. PMID: 26792515 Free PMC article.

7

Exaggerated phosphorylation of brain tau protein in CRH KO mice exposed to repeated immobilization stress.

Kvetnansky R, Novak P, Vargovic P, Lejavova K, Horvathova L, Ondicova K, Manz G, Filipcik P, Novak M, Mravec B. Kvetnansky R, et al. Among authors: novak p, novak m. Stress. 2016 Jul;19(4):395-405. doi: 10.1080/10253890.2016.1183119. Stress. 2016. PMID: 27484105

8

Safety and immunogenicity of the tau vaccine AADvac1 in patients with Alzheimer's disease: a randomised, double-blind, placebo-controlled, phase 1 trial.

Novak P, Schmidt R, Kontsekova E, Zilka N, Kovacech B, Skrabana R, Vince-Kazmerova Z, Katina S, Fialova L, Prcina M, Parrak V, Dal-Bianco P, Brunner M, Staffen W, Rainer M, Ondrus M, Ropele S, Smisek M, Sivak R, Winblad B, Novak M. Novak P, et al. Among authors: novak m. Lancet Neurol. 2017 Feb;16(2):123-134. doi: 10.1016/S1474-4422(16)30331-3. Epub 2016 Dec 10. Lancet Neurol. 2017. PMID: 27955995 Clinical Trial.

9

Stress-Induced Alterations of Immune Profile in Animals Suffering by Tau Protein-Driven Neurodegeneration.

Novak P, Cente M, Kosikova N, Augustin T, Kvetnansky R, Novak M, Filipcik P. Novak P, et al. Among authors: novak m. Cell Mol Neurobiol. 2018 Jan;38(1):243-259. doi: 10.1007/s10571-017-0491-3. Epub 2017 Apr 12. Cell Mol Neurobiol. 2018. PMID: 28405903

10

Neuropathology and biochemistry of early onset familial Alzheimer's disease caused by presenilin-1 missense mutation Thr116Asn.

Sutovsky S, Smolek T, Turcani P, Petrovic R, Brandoburova P, Jadhav S, Novak P, Attems J, Zilka N. Sutovsky S, et al. Among authors: novak p. J Neural Transm (Vienna). 2018 Jun;125(6):965-976. doi: 10.1007/s00702-018-1850-z. Epub 2018 Feb 5. J Neural Transm (Vienna). 2018. PMID: 29404783

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